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Nycomed and Forest Laboratories to Collaborate on US Commercialisation of Daxas(R) in COPD
Date:8/10/2009

lso confirmed the efficacy of Daxas when used with standard bronchodilator treatments. Full data from all four studies are to be published in a leading peer-reviewed journal later this year and will be presented at the annual European Respiratory Society (ERS) Congress in Vienna, Austria, in September.

COPD remains a significant area of unmet medical need. It is a progressive and irreversible lung disease resulting in difficulty in breathing. The disease is characterised by severe episodes of worsening, called exacerbations. According to World Health Organization (WHO) estimates, 80 million people have moderate to severe COPD worldwide. More than three million people died of COPD in 2005, which corresponds to 5% of all deaths globally. The WHO predicts that total deaths from COPD could increase by more than 30% in the next 10 years unless urgent action is taken to reduce the underlying risk factors, especially smoking.

(Seehttp://www.who.int/respiratory/copd/burden/en/index.html)

About Daxas((R))

Nycomed's Daxas( )is an orally administered phosphodiesterase 4 (PDE4) enzyme inhibitor targeting cells and mediators in the body believed to be important in the COPD disease process. Daxas is expected to act on the underlying mechanism of COPD and related inflammatory diseases. If approved, Daxas, a once-a-day tablet, will be the first drug in its class. It will also be the first new approach to the management of COPD in a generation. Current treatment for COPD patients includes the use of inhaled bronchodilators and inhaled corticosteroids.

About Forest Laboratories

Forest Laboratories (NYSE: FRX) is a U.S.-based pharmaceutical company with a long track record of building partnerships and developing and marketing p
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SOURCE Nycomed; Forest Laboratories, Inc.
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