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NxStage Reports Third Quarter 2008 Financial Results
Date:11/3/2008

study comparing clinical and economic benefits of daily home hemodialysis with thrice-weekly in-center hemodialysis.

-- In October 2008, the Company announced a new Streamline blood tubing set supply agreement with Renal Advantage, Inc.

-- In September 2008, NxStage was named the "Fastest Growing Company in Massachusetts" by the Boston Business Journal.

-- In September 2008, the Company announced a one year extension of its blood tubing set agreement with DaVita.

-- In August 2008, the Company completed a $43 million private placement of its common stock and warrants.

-- In July 2008, the Company announced access to demographic and outcomes information for its growing U.S. daily home hemodialysis patient population.

-- In July 2008, NxStage elected Jonathan Silverstein, a General Partner of OrbiMed Advisors, LLC, to its Board of Directors in connection with the recently announced private placement.

Guidance:

For the fourth quarter of 2008, the Company expects revenue to be in the range of $32 to $35 million. This is a broader than normal range for fourth quarter results reflecting lower than expected distributor inventory restocking for the Company's in-center business and the potential impact of tightened hospital capital budgets on the timing of equipment sales within the Company's critical care business. The Company expects a net loss in the range of $12.5 to $13.5 million or ($0.27) to ($0.29) per share, excluding any accounting impact of its private equity financing, and an Adjusted EBITDA loss in the range of $6.5 to $7.5 million for the fourth quarter of 2008. The Company is maintaining its fourth quarter 2008 gross margin target of 18-21%.

For the full fiscal year 2008, the Company is revising its revenue guidance to reflect its current fourth quarter revenue outlook. The Company now expects revenue in the range of $125-$128 million compared with its previous guidance of $130-$135 million.

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SOURCE NxStage Medical, Inc.
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