NxStage Medical Reports Fourth Quarter and Full Year 20...(nd grew our home hemodialysis revenues b...),Health

Recent Highlights

-- In January 2008, the Company announced that it signed a five-year

agreement with DaVita Inc. to continue to supply DaVita's dialysis

centers with MasterGuard and ButtonHole safety needle sets. Safety

needles are essential products used to access patients' blood during

the vast majority of chronic dialysis therapy treatments. MasterGuard

is the leading product in this market in the United States, and became

part of NxStage's product portfolio through the Company's acquisition

of Medisystems.

-- In November 2007, the Company announced that it entered into a $50

million credit and security agreement from a group of lenders led by

Merrill Lynch Capital, for a term of 42 months. The credit facility

consists of a $30.0 million term loan and a $20.0 million revolving

credit facility. It provides NxStage with additional financial

flexibility to support the growing needs of the Company's commercial

operations.

-- In October 2007, NxStage completed its acquisition of Medisystems

Corporation and certain affiliated entities for 6.5 million shares of

NxStage common stock. The acquisition provides NxStage with increased

commercial, operational and financial scale, positioning the Company to

maintain its leadership in the developing home hemodialysis market, and

gaining the Company a new leadership position in the United States in-

center dialysis market.

2008 Guidance

For the first quarter 2008, the Company expects revenue to be in the range of $29 million to $31 million. The Company expects a net loss in the range of $14 million to $15 million or ($0.38) to ($0.41) per share, inclu
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