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NuVasive Acquires First Stem Cell Bone Graft Substitute
Date:5/14/2008

New technologies will drive US bone graft substitute market to reach almost

$1.9 billion by 2012, according to Millennium Research Group

WALTHAM, Mass., May 14 /PRNewswire/ -- With the acquisition of Osiris Therapeutics' Osteocel business, NuVasive has obtained the first off-the-shelf bone graft substitute (BGS) product to incorporate viable stem cells. Mounting surgeon excitement about this new BGS and other innovative products will drive the BGS market to $1.9 billion in 2012, according to Millennium Research Group's US Markets for Orthopedic Biomaterials 2008 report.

"The popularity of advanced BGS technologies has increased competition within the field. Medtronic Spinal and Biologics' INFUSE BGS, based on a recombinant human bone morphogenetic protein, has forced NuVasive and other BGS competitors to dramatically innovate," says Kevin Flewwelling, Orthopedics Research Manager at Millennium Research Group. "In 2007, INFUSE sales exceeded $700 million in the US and NuVasive saw an opportunity to compete against this very successful product."

In order to compete against these advanced BGS, other manufacturers of traditional BGS products -- such as demineralized bone matrices and synthetics -- are developing next-generation products that offer improved ease-of-use and superior bone healing and regrowth. Companies claim that these new features eliminate the need for autograft bone harvested from the patient's iliac crest, reducing postoperative pain and morbidity at the donor site. With these greater advantages, surgeons are shifting towards these newer devices. A survey of surgeons conducted by Millennium Research Group found that 30.3% expected to perform fewer procedures using only autograft bone by 2012.

In addition to the BGS market, the US Markets for Orthopedic Biomaterials 2008 report covers the hyaluronic acid viscosupplementation, machined bone interbody device, knee cartilage repair, and cell concentration system ma
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SOURCE Millennium Research Group
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