Navigation Links
Novelty lures rats from cocaine-paired settings, hinting at new treatments for recovering addicts
Date:2/1/2010

WASHINGTON The brain's innate interest in the new and different may help trump the power of addictive drugs, according to research published by the American Psychological Association. In controlled experiments, novelty drew cocaine-treated rats away from the place they got cocaine.

Novelty could help break the vicious cycle of treatment and relapse, especially for the many addicts with novelty-craving, risk-taking personalities, the authors said. Drug-linked settings hold particular sway over recovering addicts, which may account in part for high rates of relapse.

In the multi-stage study, Carmela Reichel, PhD, and Rick Bevins, PhD, of the University of Nebraska-Lincoln, trained rats to prefer one side of a large Plexiglas apparatus by injecting them with one of three different doses of cocaine before placing them in that side. For the next eight days, the researchers alternated placing rats in one side or the other, injecting cocaine before placing them on one side, or injecting saline solution before placing them on the other.

This simple procedure left the rats, when drug free and given a choice, significantly more likely to visit the side where they had felt the rewarding effects of cocaine, according to the report in the February issue of Behavioral Neuroscience.

In the next stage, for another eight days, the researchers tried to break the tie between drug and place by introducing novelty. Now, when rats were placed into the saline-paired compartment, half found something new there -- a white sock, a little piece of PVC pipe, a plastic scouring pad or balled-up newspaper. The remaining rats were given the same bare compartment as before.

Next, the rats were injected with saline solution instead of cocaine and placed -- on alternate days in either the side paired with cocaine or with novelty. That would be like recovering addicts going back to the place they took drugs, a major cause of relapse. Al
'/>"/>

Contact: Public Affairs Office
public.affairs@apa.org
202-336-5700
American Psychological Association
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Weight Watchers(R) Expands Licensed Food Categories with Launch of New Baked Goods, Frozen Novelty and Cheese Products to Encourage a More Sensible Lifestyle
2. Turning metal black more than just a novelty
3. Natural Disaster Rescue Teams at Public Health Facilities Across the Country Learn from Katrina Failures
4. AIDS Vaccine Failures Highlight Need to Focus on Lifesaving Treatment, Says AHF
5. Impulsive eater? Remembering failures may help curb eating
6. Single in the City? How the Holidays Leave the Fabulous Feeling More Like Failures
7. Chemical come-on successfully lures lovesick lampreys to traps
8. Heart Transplant Failures More Likely in Poor, Minority Kids
9. Profiles International Releases New Report on Top 5 Management Failures and Remedies for Success
10. Deadly stomach infection rising in community settings, Mayo Clinic study finds
11. Drug-free treatments offer hope for older people in pain
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/14/2014)... orphaned by HIV/AIDS in South Africa may provide insight ... behavior issues in other areas of the world, which ... that could lead to successful interventions. , A ... United Nations mentions that due to the HIV/AIDS pandemic, ... African, children are at an increased risk for mental ...
(Date:4/14/2014)... A new study shows that moderate to severe ... risk of stroke, cancer and death. , Results of ... to severe obstructive sleep apnea were four times more ... times more likely to have a stroke (HR = ... (HR = 3.4), and 2.5 times more likely to ...
(Date:4/14/2014)... Dallas study involving serious youth offenders, the answer to one ... seven years: "How long do you think you,ll live?", According ... offending over time., Author Dr. Alex Piquero said the study ... of them offend at very high rates and commit more ... much later in life offend much less., "In a lot ...
(Date:4/14/2014)... with symptoms increasing dramatically during some of the most important ... has found. , Depressive symptoms increased on average by 68 ... young men, who were around 25 years old when they ... their children. The results of the study were published April ... is the first to identify when young fathers are at ...
(Date:4/14/2014)... Lower weight babies and babies who aren,t breastfed ... risk of developing chronic inflammation and related health ... study. , "There were good reasons to hypothesize ... inflammation in adulthood," says Thomas McDade (Northwestern University), ... in the Child & Brain Development program. "It ...
Breaking Medicine News(10 mins):Health News:Researchers identify children with emotional behavior difficulties 2Health News:Researchers identify children with emotional behavior difficulties 3Health News:Study links severe sleep apnea to increased risk of stroke, cancer and death 2Health News:UT Dallas study: Youth who fail to envision future commit more crimes 2Health News:Young dads at high risk of depression, too 2Health News:Low birth weight, less breastfeeding create later health risks 2
... , THURSDAY, April 28 (HealthDay News) -- Rising rates ... are cause for concern because excess weight is associated ... says. In people with arthritis, obesity is associated ... life, total joint replacement and poor outcomes after joint ...
... DC (April 28, 2011)Studies have shown that stress can ... against infection and disease. In cancer patients this ... and spread. However, the biological mechanisms that underlie ... Fox Chase Cancer Center find that poor psychosocial functioning ...
... 28 (HealthDay News) -- Use of a costly breast ... by what Medicare will pay for the treatment and ... Researchers analyzed Medicare data for 26,163 women with ... between 2001 and 2005. During that time, Medicare billing ...
... Goodwin HealthDay Reporter , THURSDAY, April 28 ... fill out while waiting to see their child,s ... suggests. Researchers recruited 137 pediatricians in the San ... screening test to fill out before seeing the doctor. ...
... (CTSN) at Emory University are focusing on prairie voles ... drugs to treat autism. They are starting ... behavioral therapy for phobias and also promotes pair bonding ... thought to facilitate learning and memory, can encourage them ...
... 2011 A program which combines interval training and ... those suffering from obesity, according to the results of ... for preventive medicine and physical activity (PIC Centre). Results ... Summit, currently taking place in Montreal. Within the ...
Cached Medicine News:Health News:Rising Obesity Rates Add to Arthritis Woes in U.S. 2Health News:Stress and depression are associated with shorter survival in head and neck cancer patients 2Health News:Payment Rates May Affect Breast Cancer Treatment 2Health News:Quick Screening May Help Spot Autism in Babies 2Health News:Quick Screening May Help Spot Autism in Babies 3Health News:Social bonding in prairie voles helps guide search for autism treatments 2Health News:Social bonding in prairie voles helps guide search for autism treatments 3Health News:Obesity: Conclusive results for the Montreal Heart Institute's EPIC Centre Kilo-Actif program 2
(Date:1/15/2014)... 2014 As health officials across the Midwest ... select Meijer pharmacies in Michigan ... throat to eligible patients, enabling Meijer pharmacists to administer ... under strict protocol set by a physician participating in ... Mich. -based retailer is collaborating with Ferris State ...
(Date:1/15/2014)... , Jan. 15, 2014 Massachusetts ... (NASDAQ: AMGN ) announced today that ... discover and validate new therapeutic targets and develop ... chronic disorder that affects millions worldwide. The MGH-Broad-Amgen ... medicine, IBD biology, human genetics, genomic technology, and ...
(Date:1/15/2014)... 2014  Manufacturers, suppliers and distributors of ... able to protect their most important business ... http://photos.prnewswire.com/prnh/20130716/CL46586LOGO ) Because ... Device Industry, it steadfastly remains one of ... involving IP infringement. This litigious nature can ...
Breaking Medicine Technology:Meijer Pharmacy Offers Free Flu, Strep Testing as Influenza Cases Rise Across the Midwest 2Meijer Pharmacy Offers Free Flu, Strep Testing as Influenza Cases Rise Across the Midwest 3Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 2Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 3Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 4Intellectual Property Insurance for Medical-related Products and Services 2
... for an AI Over Tamoxifen in,a Single Trial ... Analysis of the entire,population of a single trial ... be significantly improved by switching from,tamoxifen to anastrozole ... study, published online in The,Journal of Clinical Oncology, ...
... - Novelos,Therapeutics, Inc. (OTCBB: NVLT), a biopharmaceutical ... treat cancer and,hepatitis, today announced encouraging results ... 2 trial of NOV-002,in combination with carboplatin ... patients were evaluable for best,overall tumor response ...
Cached Medicine Technology:Anastrozole (Arimidex) Improves Overall Survival in Postmenopausal,Women with Early Breast Cancer Receiving Treatment with Tamoxifen 2Anastrozole (Arimidex) Improves Overall Survival in Postmenopausal,Women with Early Breast Cancer Receiving Treatment with Tamoxifen 3Anastrozole (Arimidex) Improves Overall Survival in Postmenopausal,Women with Early Breast Cancer Receiving Treatment with Tamoxifen 4Anastrozole (Arimidex) Improves Overall Survival in Postmenopausal,Women with Early Breast Cancer Receiving Treatment with Tamoxifen 5Novelos Therapeutics Announces Encouraging Results in Ongoing Phase,2 Ovarian Cancer Trial at Dana-Farber/Partners Cancer Care 2Novelos Therapeutics Announces Encouraging Results in Ongoing Phase,2 Ovarian Cancer Trial at Dana-Farber/Partners Cancer Care 3
Latex agglutination inhibition slide test for the qualitative detection of hCG in urine....
Test for the quantitative determination of antideoxyribonuclease-B (ADNase-B) in serum....
Hemagglutination slide test for the qualitative and quantitative detection of Rheumatoid Factor in serum or synovial fluid....
Latex agglutination slide test for the qualitative or semi-quantitative detection of infectious mononucleosis heterophile antibodies in serum or plasma....
Medicine Products: