Navigation Links
Novel treatments show improvements in survival and response rates for leukemia and lymphoma
Date:12/6/2008

with diffuse large B-cell lymphoma (23 patients), those with follicular lymphoma (21 patients), and those with other B-cell non-Hodgkin lymphomas (24 patients), including chronic lymphocytic leukemia/small lymphocytic lymphoma (11 patients), mantle cell lymphoma (nine patients), MALT lymphoma (three patients), and lymphoplasmacytic non-Hodgkin lymphoma (one patient). Patients previously received an average of five therapies, and many had previously received an autologous stem cell transplant or radioimmunotherapy.

The study found that fostamatinib disodium produced complete or partial responses in 21 percent of patients with diffuse large B-cell lymphoma, 54 percent of patients with chronic lymphocytic leukemia/small lymphocytic lymphoma, 11 percent of mantle cell lymphoma patients, and 10 percent of those with follicular lymphoma. Stable disease was also seen in an additional 23 patients, including 12 with follicular lymphoma, four with diffuse large B-cell lymphoma, four with mantle cell lymphoma, two with chronic lymphocytic leukemia/small lymphocytic lymphoma, and one with MALT lymphoma. A proportion of these responses was prolonged, with some patients remaining on therapy for more than one year. Given the refractory nature of these patients' lymphoma, the toxicity profile was quite favorable.

There were four cases of febrile neutropenia with eight patients requiring a dose-modification due to neutropenia, hypertension, liver function test abnormalities, fever, and mucositis.

Dexamethasone in Induction Can Eliminate One-Third of All Relapses in Childhood Acute Lymphoblastic Leukemia: Results of an International Randomized Trial in 3,655 Patients (Trial AIEOP-BFM ALL 2000) [Abstract #7]
Martin Schrappe, MD, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany

The results of this study found that the use of dexamethasone in the induction phase of combination chemotherapy led to a one-
'/>"/>

Contact: Laura Stark
lstark@hematology.org
415-978-3505
American Society of Hematology
Source:Eurekalert

Page: 1 2 3 4 5 6

Related medicine news :

1. Novel 3-D cell culture model shows selective tumour uptake of nanoparticles
2. Novel virus detection identifies new viruses in study of respiratory infections and asthma attacks
3. Researchers uncover novel mechanism that balances the sizes of functional areas in the brain
4. Novel Cooling Therapy May Have Aided Injured Football Player
5. ECLIPSE data on effects of Otsukas investigational novel treatment, Tolvaptan
6. SNM seeks novel approaches to molecular imaging to showcase at annual meeting
7. GrantAdler Shipping Novel Implantable Vascular Access Port
8. SNM seeks novel approaches to molecular imaging to showcase at annual meeting
9. Novel strategy under study for aggressive leukemia
10. ISTO Technologies Receives 510(k) Clearance for a Novel Bone Graft Substitute and Bone Graft Extender
11. 454 Sequencing(TM): Science Paper Describes a Novel, Highly Efficient Method of Sequencing Ancient DNA; Sequences the Mitochondria of 10 Individual Mammoths to Prove It
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/28/2014)... diabetes face a number of challenges over the holidays, but ... "With the holidays coming, take some time to think ... be visiting and all of the to-dos," Joan Bardsley, president ... association news release. "By planning ahead. you can enjoy the ... make a healthy eating contract with yourself. Before a big ...
(Date:11/28/2014)... Agein.com, the Internet’s premier anti-aging web site ... the foremost experts in the industry, is releasing its top ... winter. , “The official start of winter is still three ... hit with an icy blast. After one of the worst ... will usher in another brutal winter,” says Dr. Kevin J. ...
(Date:11/28/2014)... BambooFlooringChina.com has been recognized as a ... the business has announced its new strand woven ... discount on these new models. , Based on the ... without carpenter machines involved. It is crafted on strand ... for do-it-yourselfers without hard work on installation, also available ...
(Date:11/28/2014)... Now that the holiday season is here, ... nation's leading cash-for-junk-cars companies, is improving their cash offers ... competitive and help bring a little bit more joy ... year. , Along with purchasing expensive gifts for family ... deal with large travel expenses during the holiday season. ...
(Date:11/28/2014)... 28, 2014 Dr. Diane Walder, one ... announced the addition of Dr. Bridgit Nolan to her ... practice after having completed her dermatology residency at the ... Walder invited Dr. Nolan to join her ... and cosmetic dermatology. Not only does Dr. Nolan strive ...
Breaking Medicine News(10 mins):Health News:Holiday Eating Tips for People With Diabetes 2Health News:Agein Corporation, a Leading Anti-Aging Company, Releases Top Diet and Personal Care Tips for Preventing Dry Skin this Season 2Health News:BambooFlooringChina.com Introduces Its New Strand Woven Bamboo Flooring Collection 2Health News:Rusty's Auto Salvage Increasing Their Cash Offers to Help Drivers Save Throughout the Busy Holiday Season 2Health News:Dr. Diane Walder Welcomes New Cosmetic Dermatologist to Practice 2
... Treatment ... Worldwide, LOS ANGELES, Nov. ... develop an AIDS vaccine have,announced that their efforts have stumbled or, in ... was halted last week,when its vaccine was suspected of actually making some ...
... erosive gastroesophageal reflux disease ... (GERD) who cannot swallow tablets, COLLEGEVILLE, Pa., ... WYE ), announced today that the,U.S. Food and Drug Administration ... new addition,to the Protonix family of prescription medications. "The ...
... The prognosis for individuals with metastatic melanoma (MM) is ... have some clinical benefit; however, most patients eventually succumb ... known as dendritic cells (DCs) fail to sustain an ... in vitro using human melanoma cell lines and resected ...
... YORK, Nov. 15 Danny Wright, Chief Executive ... (http://www.alliancehealthcard.com ) will be featured in an exclusive ... at 2 p.m. EST. The interview,will be posted ... on November 16. The interview will cover ...
... will serve as Digital,s Medical Director for ... Ophthalmology, ... company specializing in retinal risk assessment for diabetics,announced today that Suber S. ... provide the company expert,advice and counsel regarding product development and development. ...
... consumption of these foods lowered odds up to 60%, study ... that includes plenty of fish, omega-3 rich oils, fruits and ... while high intake of omega-6 rich oils may boost the ... They looked at the diets of 8,085 people older than ...
Cached Medicine News:Health News:AIDS Vaccine Failures Highlight Need to Focus on Lifesaving Treatment, Says AHF 2Health News:Wyeth Receives FDA Approval of Protonix for Delayed-Release Oral Suspension 2Health News:Wyeth Receives FDA Approval of Protonix for Delayed-Release Oral Suspension 3Health News:WallSt.net Announces Upcoming Interview With CEO of Alliance HealthCard 2Health News:Digital Healthcare Announces Appointment of Dr. Suber Huang as Medical Director 2Health News:Digital Healthcare Announces Appointment of Dr. Suber Huang as Medical Director 3Health News:Fish, Fruits, Veggies May Cut Dementia Risk 2
(Date:11/28/2014)... -- Chinese magnesium alloy maker DongGuan Eontec Co., Ltd ... bone fixation screw has received Chinese regulatory inspection approval ... and that the company acknowledges receipt of the approval ... and Technology Daily journalists Wang Xiangming and ... Professor Li Yangde , has been a pioneer ...
(Date:11/27/2014)... - New Solution That Makes JINS MEME,s Raw ... Ltd. will launch JINS MEME "ACADEMIC PACK" in late April, ... (without tax /including two pairs of JINS MEME and designated ... of "JINS MEME" to academic researchers, and it enables them ... and six-axis sensors without API. (*Physiological data that can be ...
(Date:11/26/2014)... Company plc ("Perrigo") (NYSE: PRGO ; TASE), ... today announced the closing of Perrigo,s previously announced registered ... shares at a public offering price of $152.00 per ... purchase up to an additional 888,157 ordinary shares by ... representatives of the several underwriters. Perrigo ...
Breaking Medicine Technology:Chinese magnesium alloy manufacturer Eontec expects to have its medical magnesium alloy available for clinical trial in 2015 2Chinese magnesium alloy manufacturer Eontec expects to have its medical magnesium alloy available for clinical trial in 2015 3Chinese magnesium alloy manufacturer Eontec expects to have its medical magnesium alloy available for clinical trial in 2015 4JIN to Launch JINS MEME ACADEMIC PACK in Late April 2015 2JIN to Launch JINS MEME ACADEMIC PACK in Late April 2015 3Perrigo Company plc Announces The Closing Of Its Registered Public Offering Of Ordinary Shares 2Perrigo Company plc Announces The Closing Of Its Registered Public Offering Of Ordinary Shares 3Perrigo Company plc Announces The Closing Of Its Registered Public Offering Of Ordinary Shares 4
... Texas, Nov. 18, 2010 OCuSOFT, Inc., an ... to announce that ZYTAZE™ is now available in ... but are not limited to: Walgreens, CVS, Wal-Mart, ... In an early pilot study, ZYTAZE™ demonstrated marked ...
... FORD, Pa., Nov. 18, 2010 Endo Pharmaceuticals Holdings ... it priced $400 million aggregate principal amount of 7.00% ... of 99.10 percent in connection with its previously announced ... of the Company and will be guaranteed by certain ...
Cached Medicine Technology:Endo Pharmaceuticals Holdings Inc. Announces Pricing of Private Offering of Senior Notes 2
... Practice management software for eyecare ... true multi-tasking, multi-office practice management ... database technology- Winx Pro is ... assist you in effectively managing ...
... Working with over 2,500 ... proud to serve one ... client bases in the ... PM Ophthalmology, we are ...
... EMR Ophthalmology is a comprehensive electronic ... for ophthalmology practices. Intuition EMR Ophthalmology ... provides the tools to evaluate your ... to make better decisions and to ...
... in advanced cartridge mixing and delivery systems. ... mechanically injects all types of bone cement ... line-up includes a large selection of nozzles ... difficult to access areas. A new, anatomically ...
Medicine Products: