Navigation Links
Novel treatment strategies for epilepsy
Date:11/9/2012

A new EU-funded project aims to develop treatments for epilepsy by using viruses to infect brain cells and by transplanting cells into the brain. The project is called EPIXCHANGE and will be carried out at Lund University, Sweden, as a collaboration with Italian, Danish and French researchers. The total budget of the project is almost EUR 1 million.

Epilepsy is a devastating neurological disease affecting 50 million people worldwide. Patients with epilepsy run a higher risk of sudden unexpected death. In Sweden some 60 000 people suffer from epilepsy. Around 30-40% of epileptic patients are refractory to currently available pharmacological treatments, which are mostly symptomatic and often have side effects. Therefore there is a great unmet need to develop novel treatment strategies for epilepsy.

The new project will explore the development of encapsulated human cell lines producing the neurotransmitter galanin and/or the neuropeptide Y (NPY) and their effect on epileptic seizures in experimental animals. The project will also use viral vectors to deliver neuropeptides and other proteins neurotrophic factors into the brain to suppress seizures. These novel approaches will lay a foundation for developing alternative treatment strategies for epilepsy.

A viral vector approach to delivering genes of interest into the brain is already a reality. Several studies have already been performed in clinical settings in the US for Parkinson's disease. According to Professor Merab Kokaia of Lund University, the plan is to perform such clinical trials in Lund on patients with severe epilepsy that does not respond to drug treatment.

On 10 November 2012, the consortium is organising a workshop on Animal Models of Epilepsy in Lund. This workshop will discuss relevant models of epilepsy and translational aspects of the preclinical research. It is very important that the models that are used for basic research reflect human epilepsy, and that
'/>"/>

Contact: Professor Merab Kokaia
merab.kokaia@med.lu.se
46-706-620-899
Lund University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Novel compound demonstrates anti-leukemic effect in zebrafish, shows promise for human treatment
2. Rutgers team discovers novel approach to stimulate immune cells
3. Novel drug candidates offer new route to controlling inflammation
4. Researchers present new findings for novel pancreatic cancer vaccine
5. Novel biomarkers reveal evidence of radiation exposure
6. VCU Massey Cancer Center sees potential in novel leukemia treatment
7. Study supports urate protection against Parkinsons disease, hints at novel mechanism
8. Novel Natural Sciences Repository Opens Web Portal
9. Novel Anti-Inflammatories May Offer a New Approach for the Treatment of Stroke
10. LA BioMed investigators, Drs. Kevin Bruhn and Noah Craft, develop novel treatment for melanoma
11. Novel radiation therapy safely treats prostate cancer and lowers the risk of recurrence
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/25/2014)... New York (PRWEB) December 25, 2014 ... continue to move forward in a number of multidistrict ... of West Virginia, Bernstein Liebhard LLP reports. According to ... is scheduled to convene a Joint Status Conference in ... 10:00 a.m. Parties have been directed to submit a ...
(Date:12/25/2014)... North Carolina (PRWEB) December 25, 2014 ... North Carolina Retirement Community, recently showed their generous ... girls of the Catawba County Parenting Network- Grandparents ... the 10 children gathered around the largest Christmas ... to open presents purchased by residents of the ...
(Date:12/24/2014)... AlignLife of Wauwatosa loves helping ... items. During the holiday season, AlignLife looks forward to their ... says Dr. Sara Mahalko-Leonhardt, owner of AlignLife. "It brings our ... that we are able to give kids toys for Christmas ... for the generosity of our patients." , The 70 toys ...
(Date:12/24/2014)... Connie Casad, MD, a well-known and ... with 30 years of practice experience in Dallas, Texas, ... benefits of dietary detoxification. The second study is scheduled ... results from test patients who just completed a 21-day ... interest in conducting the study, Dr. Casad said, "About ...
(Date:12/24/2014)... New studies reveal that women under the age ... (March 6, 2014, JAMA Otolaryngology*). And although many people choose ... percent according to recent polls) facing hearing loss head on ... feels and relates to the world. People who have benefited ... by way of:, , self-confidence , ...
Breaking Medicine News(10 mins):Health News:Federal Court Overseeing Thousands of Transvaginal Mesh Lawsuits Set to Convene Joint Status Conference for All Litigations, Bernstein Liebhard LLP Reports 2Health News:Federal Court Overseeing Thousands of Transvaginal Mesh Lawsuits Set to Convene Joint Status Conference for All Litigations, Bernstein Liebhard LLP Reports 3Health News:Federal Court Overseeing Thousands of Transvaginal Mesh Lawsuits Set to Convene Joint Status Conference for All Litigations, Bernstein Liebhard LLP Reports 4Health News:Retirement Community Residents Make Impact During Holiday Season 2Health News:AlignLife of Wauwatosa Brings Joy to Less Fortunate Families 2Health News:Connie Casad, MD, Now Accepting Test Participants for January Dietary Detoxification Study 2Health News:Connie Casad, MD, Now Accepting Test Participants for January Dietary Detoxification Study 3Health News:Recent Studys Underscore the Fact That One of the Best Gifts to Give This Holiday Season is a Hearing Test 2Health News:Recent Studys Underscore the Fact That One of the Best Gifts to Give This Holiday Season is a Hearing Test 3Health News:Recent Studys Underscore the Fact That One of the Best Gifts to Give This Holiday Season is a Hearing Test 4Health News:Recent Studys Underscore the Fact That One of the Best Gifts to Give This Holiday Season is a Hearing Test 5Health News:Recent Studys Underscore the Fact That One of the Best Gifts to Give This Holiday Season is a Hearing Test 6
... 5 It,s official...Curamin is the natural products ... Curamin, the number-one pain-relieving product, is slated to ... Vitamin Retailer magazine in its upcoming June ... best-selling products based on a nationwide survey of ...
... Platform makes it easy for healthcare professionals to perform full "Google" ... ... Lake Forest, IL (PRWEB) May 5, 2009 -- Scribe Healthcare Technologies, ... easy for healthcare providers to conduct full "Google" like searches for ...
... May 5 Increased public and private ... of medical insurance coverage and continued foreign ... growth within the Kenyan healthcare industry. The ... continued expansion as the government boosts the ...
... DDS of Raleigh Comprehensive and Cosmetic Dentistry is one of the ... for oral sedation dentistry. , ... Raleigh, NC (PRWEB) ... L. Williamson III and Associates, announced recently that the practice has ...
... PharmaTech (NYSE: WX ) today,announced that it ... , (Logo: http://www.newscom.com/cgi-bin/prnh/20040705/CNM002LOGO ... WuXi PharmaTech, Mr. Zhou worked for eleven years at,General ... positions of increasing responsibility,in financial planning and analysis, enterprise ...
... - Revenue of $337 million declined 10.1 percent ... on U.S. hospital capital spending and foreign exchange- ... operations was $0.27 versus $0.26 in prior year, ... fully diluted share from continuing operations of $7.44 ...
Cached Medicine News:Health News:Curamin Voted Best New Natural Remedy in the Country 2Health News:Dictation, Transcription Workflow and Document Management Platform Aids Physicians In Searching For Swine Flu Symptoms 2Health News:Higher Outlays and Improved Regulatory Enforcement Create Opportunities in the Kenyan Healthcare Industry, Reveals Frost & Sullivan 2Health News:Higher Outlays and Improved Regulatory Enforcement Create Opportunities in the Kenyan Healthcare Industry, Reveals Frost & Sullivan 3Health News:Raleigh Comprehensive and Cosmetic Dentistry Earns Certification For Sedation Dentistry 2Health News:Raleigh Comprehensive and Cosmetic Dentistry Earns Certification For Sedation Dentistry 3Health News:WuXi PharmaTech Appoints Hao Zhou as Vice President of Finance 2Health News:Hill-Rom Reports Second Quarter Financial Results 2Health News:Hill-Rom Reports Second Quarter Financial Results 3Health News:Hill-Rom Reports Second Quarter Financial Results 4Health News:Hill-Rom Reports Second Quarter Financial Results 5Health News:Hill-Rom Reports Second Quarter Financial Results 6Health News:Hill-Rom Reports Second Quarter Financial Results 7Health News:Hill-Rom Reports Second Quarter Financial Results 8Health News:Hill-Rom Reports Second Quarter Financial Results 9Health News:Hill-Rom Reports Second Quarter Financial Results 10Health News:Hill-Rom Reports Second Quarter Financial Results 11Health News:Hill-Rom Reports Second Quarter Financial Results 12Health News:Hill-Rom Reports Second Quarter Financial Results 13Health News:Hill-Rom Reports Second Quarter Financial Results 14Health News:Hill-Rom Reports Second Quarter Financial Results 15Health News:Hill-Rom Reports Second Quarter Financial Results 16Health News:Hill-Rom Reports Second Quarter Financial Results 17Health News:Hill-Rom Reports Second Quarter Financial Results 18Health News:Hill-Rom Reports Second Quarter Financial Results 19
(Date:12/24/2014)... , Dec. 24, 2014 Kinex Pharmaceuticals announced ... KX2-361 at Roswell Park Cancer Institute. KX2-361 ... drug that has shown potent inhibitory activity against a ... that are resistant to Temozolomide (T98G), the most widely ... a well-established brain tumor mouse model, KX2-361 consistently clears ...
(Date:12/24/2014)... , Dec. 24, 2014  Conkwest, Inc., ... developing the proprietary Natural Killer (NK) cell-line platform, ... Dr. Patrick Soon-Shiong , NantWorks founder, physician ... definitive agreement to purchase approximately $48 million of ... with the investment, he will be named Co-Chairman ...
(Date:12/24/2014)... LONDON , December 24, 2014 ... to grow at an average rate of 8.1%. The ... volume. Hip, knee and spine surgeries are the common ... economies they have a lower penetration. Increased number of ... of composites. Non-metallic orthopedic devices have gained popularity in ...
Breaking Medicine Technology:Kinex Pharmaceuticals Announces First Patient Dosed with KX2-361 in a Phase 1 Clinical Study 2Kinex Pharmaceuticals Announces First Patient Dosed with KX2-361 in a Phase 1 Clinical Study 3Conkwest Announces $50m In Strategic Investments And Appoints NantWorks Founder, Dr. Patrick Soon-Shiong As Co-Chairman Of The Board 2Conkwest Announces $50m In Strategic Investments And Appoints NantWorks Founder, Dr. Patrick Soon-Shiong As Co-Chairman Of The Board 3Conkwest Announces $50m In Strategic Investments And Appoints NantWorks Founder, Dr. Patrick Soon-Shiong As Co-Chairman Of The Board 4Conkwest Announces $50m In Strategic Investments And Appoints NantWorks Founder, Dr. Patrick Soon-Shiong As Co-Chairman Of The Board 5Use of Composites in Orthopedic Industry to Reach $596 Million by 2020 2Use of Composites in Orthopedic Industry to Reach $596 Million by 2020 3
... recently enacted standard has replaced the Statement on Auditing ... Statement on Standards for Attestation Engagements No. 16 (SSAE ... service organizations to enforce a stronger set of controls ... http://photos.prnewswire.com/prnh/20080206/AQW030LOGO-b ) Rising Medical Solutions has taken ...
... BASIS Science, Inc., creators of the Basis™ B1 band, ... medical, social and gaming luminaries including Kevin Colleran, Charles and ... has hired Chris Verplaetse to join the company,s executive team ... to be launched later this year, the Basis B1 band ...
Cached Medicine Technology:Rising Medical Solutions, an Early Adopter of SAS 70's Replacement Standard 2Rising Medical Solutions, an Early Adopter of SAS 70's Replacement Standard 3Basis Announces Advisory Board Members from Medicine, Gaming and Social Networking 2Basis Announces Advisory Board Members from Medicine, Gaming and Social Networking 3
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: