Navigation Links
Novel treatment strategies for epilepsy
Date:11/9/2012

A new EU-funded project aims to develop treatments for epilepsy by using viruses to infect brain cells and by transplanting cells into the brain. The project is called EPIXCHANGE and will be carried out at Lund University, Sweden, as a collaboration with Italian, Danish and French researchers. The total budget of the project is almost EUR 1 million.

Epilepsy is a devastating neurological disease affecting 50 million people worldwide. Patients with epilepsy run a higher risk of sudden unexpected death. In Sweden some 60 000 people suffer from epilepsy. Around 30-40% of epileptic patients are refractory to currently available pharmacological treatments, which are mostly symptomatic and often have side effects. Therefore there is a great unmet need to develop novel treatment strategies for epilepsy.

The new project will explore the development of encapsulated human cell lines producing the neurotransmitter galanin and/or the neuropeptide Y (NPY) and their effect on epileptic seizures in experimental animals. The project will also use viral vectors to deliver neuropeptides and other proteins neurotrophic factors into the brain to suppress seizures. These novel approaches will lay a foundation for developing alternative treatment strategies for epilepsy.

A viral vector approach to delivering genes of interest into the brain is already a reality. Several studies have already been performed in clinical settings in the US for Parkinson's disease. According to Professor Merab Kokaia of Lund University, the plan is to perform such clinical trials in Lund on patients with severe epilepsy that does not respond to drug treatment.

On 10 November 2012, the consortium is organising a workshop on Animal Models of Epilepsy in Lund. This workshop will discuss relevant models of epilepsy and translational aspects of the preclinical research. It is very important that the models that are used for basic research reflect human epilepsy, and that
'/>"/>

Contact: Professor Merab Kokaia
merab.kokaia@med.lu.se
46-706-620-899
Lund University
Source:Eurekalert

0

GOOD

Page: 1 2

Related medicine news :

1. Novel compound demonstrates anti-leukemic effect in zebrafish, shows promise for human treatment
2. Rutgers team discovers novel approach to stimulate immune cells
3. Novel drug candidates offer new route to controlling inflammation
4. Researchers present new findings for novel pancreatic cancer vaccine
5. Novel biomarkers reveal evidence of radiation exposure
6. VCU Massey Cancer Center sees potential in novel leukemia treatment
7. Study supports urate protection against Parkinsons disease, hints at novel mechanism
8. Novel Natural Sciences Repository Opens Web Portal
9. Novel Anti-Inflammatories May Offer a New Approach for the Treatment of Stroke
10. LA BioMed investigators, Drs. Kevin Bruhn and Noah Craft, develop novel treatment for melanoma
11. Novel radiation therapy safely treats prostate cancer and lowers the risk of recurrence
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/19/2013)... 2013 North American Seminars combines ... course with an online continuing education course ... occupational therapists. , The two day ... an online continuing education course will ... solving skills needed to evaluate and treat dizziness ...
(Date:6/19/2013)... MA (PRWEB) June 19, 2013 ... collaboration and sensor machine software, today announced it ... for its Decentralized Fusion Engine technology. The ... and the acquisition of key strategic partnerships. ... and wireless collaboration and machine-to-machine (M2M) software products ...
(Date:6/19/2013)... Francisco, CA (PRWEB) June 19, 2013 The ... sized tents is because users can place a 4x8 flood ... clearance boundary space to work around. In addition, Gorilla ... tents. Because they are the tallest, thickest and strongest grow ... new bar for grow tent standards. , Gorilla ...
(Date:6/19/2013)... Tornadoes and their devastating aftermath have increased across the ... to these deadly storms find it hard to recover. ... and corporations from natural and man-made disasters for over ... philosophy of providing a storm shelter that can be ... stand up, with light and a battery-operated blower for ...
(Date:6/19/2013)... DC (PRWEB) June 19, 2013 ... in the history of managed care. As many ... coverage through the new state-based and federally operated ... for essential health benefits, and examples of premium ... states, industry-leading health business information publisher Atlantic Information ...
Breaking Medicine News(10 mins):Health News:New Evidence Based Information on Treatment for Over 8 Million People in the U.S. Affected With Disorders of the Vestibular System 2Health News:Blueforce Awarded Patent for Decentralized Sensor Fusion 2Health News:Stealth Grow Tent Brand’s Popularity Rises 2Health News:Radius Engineering International Inc. Tornado-Resistant Storm Shelters 2Health News:New Special Report Provides Comprehensive Overview of New Health Insurance Exchange Marketplaces 2
... could help many avoid stroke , , THURSDAY, Jan. 24 (HealthDay ... for preventing strokes was stopped early because of excess bleeding, ... researchers said the trial could open the way to at ... seems to occur primarily in two groups of people -- ...
... Preserve Competition in Three Clinical Testing,Markets, WASHINGTON, ... that it will require Pearson Plc to divest ... to proceed with,Pearson,s proposed $950 million acquisition of ... originally proposed, would have,resulted in higher prices to ...
... of,Health and Human Services (HHS) Secretary Mike ... developed by the Healthcare Information,Technology Standards Panel ... three,of its "Interoperability Specifications" to help support ... Nationwide Health Information Network in,the United States ...
... disease ulcerative colitis are at increased risk of developing ... colleagues at Kanazawa University, Japan, identified a central role ... colon cancer in mice in which inflammation of the ... by repeated dextran sulfate sodium (DSS) ingestion. Expression of ...
... The U.S. Department of,Labor today announced a $1,250,000 ... to help provide assistance in paying health insurance,premiums ... for the,Health Coverage Tax Credit. The assistance is ... of 2002., "This $1.25 million grant will ...
... SCOTTSDALE, Ariz., Jan. 24 DC Ranch Village ... literally. The latest yoga class,Chocolate-Covered Yoga, teaches yogis how ... but also how to heighten the senses, and experience,sensations ... eating., The class is a very fulfilling yoga ...
Cached Medicine News:Health News:Anti-Clotting Drug Trial Shortened by Bleeding Problems 2Health News:Justice Department Requires Divestitures in Pearson's Acquisition of Harcourt Assessment 2Health News:Justice Department Requires Divestitures in Pearson's Acquisition of Harcourt Assessment 3Health News:HHS Secretary Recognizes Products of HITSP Standards Work 2Health News:HHS Secretary Recognizes Products of HITSP Standards Work 3Health News:HHS Secretary Recognizes Products of HITSP Standards Work 4Health News:U.S. Department of Labor Announces $1.25 Million to North Carolina to Help Trade-Affected Workers Pay for Health Insurance 2Health News:DC Ranch Village Health Club & Spa Twists with Chocolate Yoga Class 2
(Date:6/18/2013)... -- , Safinamide significantly improves responder ... add-on to levodopa Safinamide is associated ... fluctuating PD patients as add-on to levodopa ... a research and development company focused on novel ... S.p.A., a pharmaceutical company strongly committed to the ...
(Date:6/18/2013)... June 18, 2013 Valeant Pharmaceuticals International, Inc. ... priced its previously announced public offering of common shares ... issue 23,529,412 common shares at a price of $85.00 ... billion. The Company will file a final prospectus supplement ... and will make a similar filing with the securities ...
(Date:6/18/2013)... ROCKY HILL, Conn. , June 18, 2013 ... many past clients of Alliance Seating and Mobility, ... now unable to access timely repair. This appears ... and a dramatic reduction of field service employees.  ... Unfortunately a great many of these clients ...
Breaking Medicine Technology:Safinamide Phase III Study Results Presented at 2013 MDS Meeting 2Safinamide Phase III Study Results Presented at 2013 MDS Meeting 3Safinamide Phase III Study Results Presented at 2013 MDS Meeting 4Safinamide Phase III Study Results Presented at 2013 MDS Meeting 5Safinamide Phase III Study Results Presented at 2013 MDS Meeting 6Valeant Pharmaceuticals Prices Public Offering Of Common Shares 2Valeant Pharmaceuticals Prices Public Offering Of Common Shares 3Valeant Pharmaceuticals Prices Public Offering Of Common Shares 4
... Calif., Aug. 31, 2011 Onyx Pharmaceuticals, ... it has appointed Helen Torley, M.B. Ch. B., M.R.C.P., ... her role, Dr. Torley will report to N. Anthony ... be responsible for all commercial activities related to Nexavar ...
... MOUNTAIN VIEW, Calif., Aug. 31, 2011 Concentric Medical, ... today announced that Stryker Corporation (NYSE: SYK ... Medical for $135 million in an all-cash transaction. The ... early in the fourth quarter of 2011. ...
Cached Medicine Technology:Onyx Pharmaceuticals Appoints Dr. Helen Torley as Chief Commercial Officer 2Onyx Pharmaceuticals Appoints Dr. Helen Torley as Chief Commercial Officer 3STRYKER Signs Definitive Agreement to Acquire CONCENTRIC MEDICAL, Inc. 2
The CALBIOTECH, INC. (CBI), Mumps IgM ELISA tests system is an enzyme linked immunosorbent assay (ELISA) for the detection of IgM class antibodies to Mumps in human serum or plasma....
The DSL-05-10-MUG Mumps IgG Enzyme-Linked Immunosorbent Assay (ELISA) kit provides materials for the determination of IgG-class antibodies to Mumps Virus in human serum. This assay is intended for in...
... Xact stent is self-expanding and has a closed-cell ... flexible mesh intended to help restore the inner ... inner vessel surface, and potentially reduce the release ... when it is treated, which can lead to ...
... With BareWire technology, the wire crosses the ... delivery catheter. All other actions, including filter ... placement then occur over the wire., ,Emboshield ... break off during a carotid stenting procedure, ...
Medicine Products: