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Novel therapeutic agents provide hope for patients with hard-to-treat blood disorders
Date:12/9/2012

B remained in the study. The primary reason cited for discontinuation was progressive disease, which occurred in 35 percent of patients in Arm A and 49 percent in Arm B. One-fourth (25%) of patients in Arm A and 38 percent in Arm B died during the study, primarily from advanced disease and infections.

"We are excited about these results, as they show that a combination approach with pomalidomide and low-dose dexamethasone offers superior results than current treatment options for hard-to-treat myeloma patients," said Meletios Dimopoulos, MD, lead author and Professor and Chairman of the Department of Clinical Therapeutics at Alexandra Hospital in Athens, Greece. "We believe this study provides the basis to consider this combination as a new standard of care for patients who have exhausted most standard treatments to treat their refractory disease and may even offer greater benefit if studied among less heavily treated patients as a first-line therapy for the disease."

Dr. Dimopoulos will present this study during the Late Breaking Abstracts session on Tuesday, December 11, at 7:30 a.m. EST at the Georgia World Congress Center in Hall B5, Level 1, Building B.


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Contact: Andrea Slesinski
aslesinski@hematology.org
614-352-5096
American Society of Hematology
Source:Eurekalert

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