Navigation Links
Novel technique increases detection rate in screening mammography

OAK BROOK, Ill. Digital mammography screening with new photon-counting technique offers high diagnostic performance, according to a study published online in the journal Radiology.

As mammography screening has shifted to digital technology, a range of computed radiography (CR) and direct radiography (DR) systems have emerged. The photon-counting technique is a promising DR approach that uses a unique detector to decrease scattered radiation and noise, enabling dose reduction and making it a promising tool for screening.

"In population-based mammography screening, dose reducing techniques that don't compromise outcome parameters are desirable," said Walter Heindel, M.D., from the Department of Clinical Radiology at the University Hospital Muenster in Muenster, Germany.

For the study, Dr. Heindel and colleagues analyzed data from the mammography screening program in North Rhine-Westphalia, the most populous state in Germany. They compared the screening performance of a DR photon-counting scan system with those of statewide operating screening units using different digital technologies. During the study period (2009 2010), 13,312 women were examined using the photon-counting system, and 993,822 women were screened with either CR or DR systems alone.

The DR photon-counting scan system had a cancer detection rate of 0.76 percent for subsequent screening, compared with 0.59 percent for the other screening units. The recall rate was 5.4 percent for the photon-counting method and 3.4 percent for the other methods.

"The higher cancer detection resulting from the use of the DR photon-counting scan system is due to high detection of both small, invasive cancers and ductal carcinoma in situ," Dr. Heindel said.

The photon-counting technique had almost twice the detection rate of other methods for ductal carcinoma in situ (DCIS), an early, noninvasive form of disease. It had a higher DCIS detection rate than the statewide units and the conventional DR subgroup.

In addition, the mean average glandular radiation dose of the DR photon-counting scan system was significantly lower than the conventional DR systems with the individually used parameters of the automatic exposure control.

The study's large size distinguishes it from previous studies that compared the DR photon-counting scan system's performance with other approaches.

"To our knowledge, the study is different from previous ones as we examined the performance of the DR photon-counting scan mammography on a larger database with consideration of multiple parameters of screening," said study coauthor Stefanie Weigel, M.D., from the University Hospital Muenster.

The photon-counting technique also offers lateral dose modulation during the image acquisition, which can help account for differences in breast density. Cancer often is more difficult to detect in women with dense breasts.

"The innovative photon-counting technique offers further research potential," Dr. Heindel said. "One future research direction is the application of spectral imaging for quantification of breast glandular tissue, addressing the problem of breast density."


Contact: Linda Brooks
Radiological Society of North America

Related medicine news :

1. Researchers find novel approach for controlling deadly C. difficile infections
2. Novel genes determine division of labor in insect societies
3. Novel biomarker approach suggests new avenues to improve schizophrenia disease management
4. Development of a novel dual JAK/Src kinase inhibitor
5. Jesus Was Not Born On December 25th - Controversial New Novel Tells Compelling Story About His Birth, Life and Death
6. Fatigue, a common side effect of breast cancer treatment, evaluated in novel patient study
7. Novel drug regimen can improve stem cell transplantation outcomes
8. NIST calibration tools to encourage use of novel medical imaging technique
9. Successful repair of bone defects using a novel tissue engineered bone graft
10. Novel rehabilitation device improves motor skills after stroke
11. Icahn School of Medicine at Mount Sinai awarded $2.7 million from NIH to investigate novel therapy for eczema
Post Your Comments:
Related Image:
Novel technique increases detection rate in screening mammography
(Date:11/27/2015)... , ... November 27, 2015 , ... According to an ... not changing the way that they are handling security in light of the recent ... security presence in an attempt to stop an attack from reaching U.S. soil. Especially ...
(Date:11/27/2015)... ... 27, 2015 , ... Lizzie’s Lice Pickers just announced a special promotion that ... of their purchase of lice treatment product. In addition, customers will receive a complimentary ... spokesperson. “Finding lice is a sure way to ruin the holidays, so we encourage ...
(Date:11/27/2015)... ... November 27, 2015 , ... Intellitec Solutions announced ... User Group (MSDSLUG). Recognized as Microsoft’s official group for end users of Dynamics ... software users, partners, industry experts and representatives. Intellitec Solutions’ membership status demonstrates their ...
(Date:11/27/2015)... ... November 27, 2015 , ... The men and women ... healthcare organizations in the country. They have overseen financial turnarounds, shown commitment to ... the healthcare industry as a whole through their advocacy and professional efforts. , ...
(Date:11/26/2015)... ... November 26, 2015 , ... Inevitably when people think Thanksgiving, they ... to buy during the Black Friday and Cyber Monday massage chair sales ... the Internet high and low to find the best massage chair deals, they can ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... DUBLIN , November 26, 2015 ... has announced the addition of the  ... in the European Therapeutic Drug Monitoring ... Forecasts, Competitive Intelligence, Emerging Opportunities"  report ... ) has announced the addition ...
(Date:11/26/2015)... , November 26, 2015 ... addition of the "Radioimmunoassay Market by ... (Hospital, Pharmaceutical Industry, Academics, Clinical Diagnostic Labs), ... Global Forecast to 2020" report to ... has announced the addition of the ...
(Date:11/25/2015)... THOUSAND OAKS, Calif. , Nov. 25, 2015 /PRNewswire/ ... of a Biologics License Application (BLA) with ... Administration (FDA) for ABP 501, a biosimilar candidate to ... the first adalimumab biosimilar application submitted to the FDA ... biosimilar pathway. Sean E. Harper , M.D., ...
Breaking Medicine Technology: