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Novel research set to pinpoint risk of heart attacks and strokes
Date:9/21/2011

A simple blood test is all it could take to tell if you are going to have a heart attack or stroke. A team of international scientists have discovered more than 10 types of unique proteins which are commonly present in the blood of a person who recently suffered a stroke or heart attack.

The breakthrough is a result of an international collaboration led by Nanyang Technological University (NTU)'s lead scientist, Assistant Professor Newman Sze, and the Interuniversity Cardiology Institute of the Netherlands (ICIN)'s lead cardiology scientist, Professor Dominique de Kleijn, who have been working together for more than five years. Lead clinicians Professor Lee Chuen Neng and Dr. Vitaly Sorokin of the National University Hospital (NUH) joined the research team in 2010 to provide medical expertise, clinical samples and data.

The team will now expand their research to study the existence of these proteins, also known as bio-markers, in Singapore's multi-racial population.

Their research is expected to result in the development of a sensitive diagnostic tool possibly in the form of a simple blood test - which can detect these bio-markers so as to help pinpoint the risk of heart diseases in a person before it happens. This is because the more such biomarkers are found in the blood, the higher the risk of a heart attack or stroke.

As these biomarkers are newly discovered, specialised instruments are needed for further research. To this end, Agilent Technologies Inc. (NYSE: A), the world's premier measurement company and a technology leader in communications, electronics, life sciences and chemical analysis, will be partnering NTU to provide top-of-the-line equipment to NTU.

The equipment is used to identify and validate more protein biomarkers associated with cardiovascular diseases. Known as the Agilent HPLC-Chip LC/MS Triple Quadrupole system, this equipment works much faster than other existing methods as it can measure
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Contact: Lester Kok
lesterkok@ntu.edu.sg
65-679-06804
Nanyang Technological University
Source:Eurekalert

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