Navigation Links
Novel radiation therapy safely treats prostate cancer and lowers the risk of recurrence
Date:6/26/2012

Richmond, Va. (June 22, 2012) A recent Phase I/II clinical trial has shown that a new combination of radiation therapies developed at Virginia Commonwealth University Massey Cancer Center escalates radiation doses to safely and effectively treat prostate cancer and lower the risk of recurrence with minimal radiation exposure to nearby healthy tissue and organs.

Recently published in the journal Brachytherapy, a novel treatment protocol designed by Michael Hagan, M.D., Ph.D., radiation oncologist at VCU Massey Cancer Center, that combines intensity-modulated radiation therapy with high-dose rate (HDR) brachytherapy was tested on 26 prostate cancer patients. Intensity-modulated radiation therapy uses computer-controlled linear accelerators to modulate the intensity of an external radiation beam to more accurately deliver radiation to tumors. HDR brachytherapy is an internal form of radiation therapy that uses small radioactive pellets implanted near the tumor.

"Recent studies have shown that both higher daily doses and higher total doses of radiation are better than standard doses in controlling prostate cancer, but these higher doses may be associated with higher rates of bladder and bowel complications," says the study's lead author Mitchell Anscher, M.D., Florence and Hyman Meyers Chair of Radiation Oncology and program co-leader of Radiation Biology and Oncology at VCU Massey Cancer Center. "Our study was designed to reduce radiation exposure to nearby healthy tissue and organs and we were pleased to find that this unique dosing schedule is safe and effective."

The toxicity of the therapy was relatively low and all 26 patients were able to complete treatment. The treatment required only one HDR brachytherapy implant, and all participants were treated as outpatients. After 4.5 years, none of the patients relapsed and the rate of long-term side effects was low.

"Our goal is to improve outcomes for our patients, so we are continually researching ways to reduce unnecessary radiation exposure to healthy tissues and make treatments shorter and more manageable. We're hopeful our findings will lead to better tumor control rates and fewer complications for men with prostate cancer," says Anscher.

Moving forward, the researchers plan to continue exploring prostate cancer therapies using higher dose rates and shorter treatment times. The next step will likely be a four-treatment study utilizing stereotactic body radiosurgery, a technique popular with brain cancer that provides higher accuracy and requires fewer treatments by focusing high-powered X-rays on a very small area.


'/>"/>

Contact: John Wallace
wallacej@vcu.edu
804-628-1550
Virginia Commonwealth University
Source:Eurekalert

Related medicine news :

1. LA BioMed investigators, Drs. Kevin Bruhn and Noah Craft, develop novel treatment for melanoma
2. Novel Anti-Inflammatories May Offer a New Approach for the Treatment of Stroke
3. Novel Natural Sciences Repository Opens Web Portal
4. Study supports urate protection against Parkinsons disease, hints at novel mechanism
5. VCU Massey Cancer Center sees potential in novel leukemia treatment
6. Novel biomarkers reveal evidence of radiation exposure
7. Researchers present new findings for novel pancreatic cancer vaccine
8. Novel drug candidates offer new route to controlling inflammation
9. Rutgers team discovers novel approach to stimulate immune cells
10. Novel compound demonstrates anti-leukemic effect in zebrafish, shows promise for human treatment
11. Limited Radiation May Help Some Kids With Lymphoma
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/30/2016)... ... 30, 2016 , ... "This plugin comes with 60 customizable ... CEO of Pixel Film Studios. , TransPack Volume 7 features over 60 ... abstract transitions to more simple wipes with blur & drop shadow options. Utilize ...
(Date:5/30/2016)... ... 30, 2016 , ... Another ER facility operated by First Choice Emergency ... Drive, Plano, TX and is open 24 hours daily. , First Choice Emergency Room ... open house. The Jasper High School band entertained attendees and accepted First Choice Emergency ...
(Date:5/29/2016)... ... May 29, 2016 , ... "With 30 unique self-animating web themed intros and ... of their project," said Christina Austin - CEO of Pixel Film Studios. , ... for use in Final Cut Pro X. Pixel Film Studios’ minimalistic titles allow users ...
(Date:5/28/2016)... ... ... May 26, 2016- In search of the K. Warriors, Shaolin Institute is ... Warriors” on June 4, 2016 at Ashbury Hotel and Suites 600 West Interstate 65 ... by Shaolin Institute and sanctioned by KSF (Kungfu Sanda Federation), This is the 28th ...
(Date:5/27/2016)... (PRWEB) , ... May 27, 2016 , ... More than ... so it is not surprising that bariatric surgery has received increased attention in recent ... explains. Of course, when it comes to weight loss, most people are familiar with ...
Breaking Medicine News(10 mins):
(Date:5/26/2016)... 2016 According to a new market ... - U.S. Industry Analysis, Size, Share, Growth, Trends, and Forecast ... U.S. was valued at US$ 5.89 Bn in 2014 and ... 2015 to 2023 to reach US$ 7.99 Bn in 2023. ... emerging needle free drug delivery devices and the market is ...
(Date:5/26/2016)... TARE (Transarterial Radio-embolization) Using ... and Overall Decreased Use of Hospital Resource ... specialist healthcare company, has today announced the publication ... of ISPOR (International Society for Pharmacoeconomics and Outcomes ... using yttrium-90 glass microspheres is associated with cost ...
(Date:5/26/2016)... Massachusetts , May 26, 2016 ... (NGS) has matured into an essential life science tool ... and development applications. BCC Research reveals in its new ... a second growth phase, one powered by a range ... fields.      (Logo: http://photos.prnewswire.com/prnh/20140723/694805 ) ...
Breaking Medicine Technology: