Novel mechanism found that may boost impaired function of leukem...(ndings to help develop and ultimately te...),Health

Date:2/29/2008

ndings to help develop and ultimately test new treatment strategies for patients with either myeloid or lymphoid types of acute leukemia, said the studys first author, Xinyang Zhao, a member of Dr. Nimers laboratory.

Dr. Nimer has been researching the AML1-ETO protein at MSKCC since 1993. He and his colleagues first demonstrated in 1995 that AML1-ETO functions as a transcriptional repressor and dominantly inhibits AML1 function.

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Contact: Esther Napolitano napolite@mskcc.org 212-639-3139 Memorial Sloan-Kettering Cancer Center Source:Eurekalert

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