Navigation Links
Novel brain tumor vaccine acts like bloodhound to locate cancer cells
Date:1/5/2012

tumor growth. If the stem cells aren't targeted, they keep generating more tumors."

According to the biotechnology company that is conducting the trial, the Phase I clinical study of ICT-107 in GBM involved 16 newly-diagnosed patients who received the vaccine in addition to standard therapy surgery, radiation and chemotherapy. Those patients demonstrated a one-year overall survival of 100 percent and a two-year survival of 80 percent. Although only a small number of patients were treated, these results compare favorably with historical 61percent one-year and 26 percent two-year survival with standard care alone.

Vaccines for brain tumors are new and experimental, said Lesser, but are gaining more attention in the glioma world.

"Vaccines are a way to harness the body's own defenses which are usually used to ward off or control infections like the flu to fight cancer cells instead," Lesser explained. "It is a way of presenting antigens or proteins normally found on the surface of the cancer cells to the immune system so that immune cells can seek out and kill those cancer cells anywhere in the body. This is not unlike giving a piece of clothing to a bloodhound and then letting it loose to find a missing person."

Wake Forest Baptist is also involved in another brain tumor vaccine trial for patients with low-grade or slower growing gliomas. Among the targets of both of these vaccines is a new protein found on the surface of glioma cells discovered by Waldemar Debinski, M.D., Ph.D, director of the Wake Forest Baptist Brain Tumor Center of Excellence.

"Early studies of vaccines for patients with brain tumors are showing promising results," Lesser said. "We want to help definitively determine how good these novel therapies really are for patients."


'/>"/>

Contact: Bonnie Davis
bdavis@wakehealth.edu
336-716-4977
Wake Forest Baptist Medical Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Novel Hepatitis C Vaccine Shows Some Early Promise
2. BUSM researchers identify novel compound to halt virus replication
3. Novel technique could help boost IVF success and reduce multiple pregnancies
4. Novel export-inhibitor shows promise for treating CLL
5. Novel experimental agent is highly active in CLL patients, interim study shows
6. Researchers identify a novel therapeutic approach for liver cancer
7. Novel drug wipes out deadliest malaria parasite through starvation
8. Novel approach to treating breast cancer shows great promise
9. Wayne State receives $1.9 million from NIH to create novel cystic fibrosis treatments
10. Novel ALS drug slows symptom progression, reduces mortality in phase 2 trial
11. Wayne State University to study novel treatment for antibiotic-resistant bacteria
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/21/2014)... of preterm birth the birth of an infant ... significant health problem that has increased over the past ... Control and Prevention (CDC), preterm birth affects nearly 500,000 ... in the U.S. While medical care has improved survival ... positively impact the neurodevelopmental outcomes of preterm infants. , ...
(Date:9/21/2014)... of the leading online stores of real and synthetic hair ... human hair lace wigs inspired by 6 famous celebrities. It’s ... latest celebrity hairstyles are. , For people who ... to choose from: a style of yaki straight lace wig, ... ombre red lace wig. People can go to the product ...
(Date:9/21/2014)... public health authorities focus on the physical activity benefits ... of Montreal reveals that for children, playing has no ... activity that is fun, done alone or with friends, ... pleasure, but also to combat boredom, sadness, fear, or ... play, authorities put aside several aspects of play that ...
(Date:9/21/2014)... Dry roasted peanuts are more likely to trigger an ... University study involving mice. , The researchers say that ... the dry roasting process are recognised by the body,s ... allergic immune response the next time it sees any ... the number of people with peanut allergies in the ...
(Date:9/21/2014)... The Laboratory Testing Services industry is composed ... on items ranging from consumer and food products to ... operators to ensure the safety and quality of their ... government safety regulations and consumer lawsuits have led to ... revenue briefly dipped in 2009 as the US economy ...
Breaking Medicine News(10 mins):Health News:Research evaluates neurodevelomental and medical outcomes in single family room NICU 2Health News:Research evaluates neurodevelomental and medical outcomes in single family room NICU 3Health News:UniWigs New Arrivals Just In- Human Hair Lace Wigs Inspired By Famous Celebrities 2Health News:Narrow focus on physical activity could be ruining kids' playtime 2Health News:Dry roasting could help trigger peanut allergy 2Health News:Laboratory Testing Services in the US Industry Market Research Report from IBISWorld Has Been Updated 2Health News:Laboratory Testing Services in the US Industry Market Research Report from IBISWorld Has Been Updated 3
... 3 Nanophase Technologies (Nasdaq: ... and advanced nanoengineered products, announced today that the Company ... 28th, as its Chief Technology Officer, so that he ... was responsible for several of the Company,s key patents ...
... National Center for Health Care Informatics (NCHCI) Presented Pilot ... a Patriot Scientific company (OTC Bulletin Board: PTSC), announced ... and the National Center for Health Care Informatics (NCHCI), ... a presentation today by Raymond F. Rogers, chief executive ...
... brand made specifically for kids by kids and their ... WAT-AAH!, the first sugar-free, functional water brand made specifically ... first official "WAT-AAH! Challenge" to defy the expectation that ... the month of March, mothers who participate in the ...
... released today by Dr. Jane L. Delgado, President and ... nation,s leading Hispanic health advocacy group."We congratulate Governor Sebelius ... Health and Human Services and Nancy-Ann DeParle on her ... Health Reform."The nation will be well served at this ...
... Inc. (Nasdaq: GTIV ), a leading provider ... plans to present at two upcoming investor conferences. Gentiva ... in Miami, Florida from 9:30 a.m. to 9:55 a.m. ... Annual Raymond James Institutional Investor Conference in Orlando, Florida ...
... meal of the day has surprising impact on young ... awareness for the importance of breakfast for students, Sodexo, ... more than 470 school districts across the country, has ... Students" in time for National School Breakfast Week, March ...
Cached Medicine News:Health News:Nanophase Announces Changes in Principal Officers and Directors 2Health News:Nanophase Announces Changes in Principal Officers and Directors 3Health News:Crossflo Health Information Exchange Project Presented at HP Health and Life Sciences Symposium 2Health News:Crossflo Health Information Exchange Project Presented at HP Health and Life Sciences Symposium 3Health News:Let Water Be Water, LLC Introduces New 'WAT-AAH! Challenge' 2Health News:National Alliance for Hispanic Health Congratulates Governor Kathleen Sebelius and Nancy-Ann DeParle 2Health News:Gentiva(R) Health Services to Present at Upcoming Investor Conferences 2Health News:Gentiva(R) Health Services to Present at Upcoming Investor Conferences 3Health News:Sodexo Shares Top Breakfast Benefits for Students 2
(Date:9/20/2014)... 2014 /CNW/ - The issue: Mylan Pharmaceuticals ULC Canada, in ... its Mylan-Nitro Spray 0.4 mg/metered dose due to the product ... component. A missing "dip tube" could pose ... patient. This defect may lead patients to believe they are ... access it. Not receiving nitroglycerin could place them at risk ...
(Date:9/19/2014)... Pa. , Sept. 19, 2014  Today ... two new variable angle plating systems featuring its ... surgeons can adapt screw trajectory to match patient ... specific fragments of bone. The systems are being ... & Ankle Society (AOFAS) and the International Federation ...
(Date:9/19/2014)... Calif. , Sept. 19, 2014 Today, iHealth ... capital from Xiaomi Ventures, Ltd. for its first institutional ... to continue expanding iHealth,s global reach, accelerate growth and ...  As part of the investment, Xiaomi Ventures will join ... areas of cloud infrastructure and ecommerce. "We ...
Breaking Medicine Technology:Advisory - Mylan Pharmaceuticals recalling nitroglycerin spray due to defective pump 2DePuy Synthes Proprietary Variable Angle Locking Technology Now Available To Treat Calcaneal Fractures And Medial Column Fusion Procedures 2DePuy Synthes Proprietary Variable Angle Locking Technology Now Available To Treat Calcaneal Fractures And Medial Column Fusion Procedures 3iHealth Raises $25 Million to Fuel Growth and Global Market Share 2
... , SAN DIEGO, Oct. 15 Prometheus Laboratories ... announced the nationwide commercial launch of three new ... Dx and ProOnc Mesothelioma Dx. Each of these ... microRNA technology. , "Prometheus has a long and ...
... HOLLYWOOD, Fla. and PRINCETON, N.J., Oct. 15 ... preclinical and pharmaceutical product development services and PharmaNet ... development services to innovative pharmaceutical, biotechnology, generic drug ... the completion of a business development and co-promotion ...
Cached Medicine Technology:Prometheus Launches ProOnc Dx Cancer Diagnostics 2Prometheus Launches ProOnc Dx Cancer Diagnostics 3Azopharma and PharmaNet Development Group Enter Preclinical Strategic Alliance 2
... powerful, lightweight, easy to ... durable foam silicone rubber ... by machine washable cotton ... easily adjusts to all ...
... powerful, lightweight, easy to ... durable foam silicone rubber ... by machine washable cotton ... easily adjusts to all ...
Xenon surgical headlight system is durable, comfortable, lightweight and deliver dependable bright light through a patented shielded fiber optic bundle. It is easy to wear....
Solarc surgical headlight is durable, comfortable, lightweight and delivers the bright, white light expected from a xenon system, but at a fraction of the cost....
Medicine Products: