Navigation Links
Novel brain tumor vaccine acts like bloodhound to locate cancer cells
Date:1/5/2012

WINSTON-SALEM, N.C. Jan. 5, 2012 A national clinical trial testing the efficacy of a novel brain tumor vaccine has begun at Wake Forest Baptist Medical Center, the only facility in the Southeast to participate.

The vaccine will be tested in patients with newly diagnosed glioblastoma multiforme (GBM), the most aggressive and highest grade malignant glioma. Wake Forest Baptist will treat a minimum of 25 patients in this randomized, placebo-controlled phase II clinical trial of ICT-107. A total of 20 sites across the country are participating in the trial to test the safety and efficacy of this novel cancer vaccine.

All patients enrolled in the study will receive the current standard treatment for GBM, which includes surgery followed by radiation and chemotherapy. Two thirds of the participants will then also get the experimental vaccine treatment, which will be administered in the post radiation phase of treatment, while the others will get a "dummy," or placebo vaccine in addition to standard therapy.

"This vaccine is for newly-diagnosed patients," said Glenn Lesser, M.D., a professor of internal medicine, hematology-oncology, at Wake Forest Baptist and principal investigator for the study. "Scientifically, it's a very well designed study and we are excited to participate in this clinical trial. We've been asked to participate based on our reputation as an outstanding brain tumor center and the expertise our center has with bringing novel therapies and novel therapeutics to patients."

The approach with this particular vaccine is unique, Lesser added, because it is targeting the antigens or proteins that are present on glioma stem cells, whereas other treatment approaches mostly target differentiated tumor cells.

"The antigens used in this vaccine target the tumor stem cells the handful of cells that keep the tumor alive and dividing. Most of the cells we kill with standard treatment are likely not the ones driving the
'/>"/>

Contact: Bonnie Davis
bdavis@wakehealth.edu
336-716-4977
Wake Forest Baptist Medical Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Novel Hepatitis C Vaccine Shows Some Early Promise
2. BUSM researchers identify novel compound to halt virus replication
3. Novel technique could help boost IVF success and reduce multiple pregnancies
4. Novel export-inhibitor shows promise for treating CLL
5. Novel experimental agent is highly active in CLL patients, interim study shows
6. Researchers identify a novel therapeutic approach for liver cancer
7. Novel drug wipes out deadliest malaria parasite through starvation
8. Novel approach to treating breast cancer shows great promise
9. Wayne State receives $1.9 million from NIH to create novel cystic fibrosis treatments
10. Novel ALS drug slows symptom progression, reduces mortality in phase 2 trial
11. Wayne State University to study novel treatment for antibiotic-resistant bacteria
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... January 22, 2015 Four years since the release ... which coincided with the marriage of Avasa & Matthew Love – ... which is scheduled for release through White Swan Records on February ... there is a sacred path available to all of us to ...
(Date:1/22/2015)... Mass. (PRWEB) January 22, 2015 EBSCO ... (AMA) are expanding their relationship in an effort to ... around the world. While EBSCO has long made AMA journals ... a sales agent for The JAMA Network. , ...
(Date:1/22/2015)... JJsHouse.com is a famous dress online store for ... its latest collection of wedding dresses , and launches ... is the wedding dress on your big day; the wedding ... Every bride wants to find the most suitable wedding dress. ...
(Date:1/22/2015)... Lower-Auto-Insurance.com has released a new blog post explaining the ... reducing the costs of an auto insurance policy . ... get lower prices for their vehicle insurance policies. The safety a ... policy costs. Because of this, drivers should always carry a ...
(Date:1/22/2015)... 22, 2015 State Forestry Institute of ... system with support from GEOSYSTEMS, a dedicated Hexagon Geospatial ... will leverage Hexagon Geospatial’s ERDAS APOLLO for ... well as point clouds and documents. This effort will ...
Breaking Medicine News(10 mins):Health News:THE ROAD by Avasa & Matthew Love -- A New Album 2Health News:THE ROAD by Avasa & Matthew Love -- A New Album 3Health News:THE ROAD by Avasa & Matthew Love -- A New Album 4Health News:EBSCO Expands Partnership with the American Medical Association 2Health News:EBSCO Expands Partnership with the American Medical Association 3Health News:EBSCO Expands Partnership with the American Medical Association 4Health News:Find The Most Suitable Wedding Dress At JJsHouse.com 2Health News:Driving Safe And Other Factors That Make Auto Insurance Affordable! 2Health News:State Forestry Institute Mecklenburg-Vorpommern, Germany Embraces Hexagon Geospatial Technology 2Health News:State Forestry Institute Mecklenburg-Vorpommern, Germany Embraces Hexagon Geospatial Technology 3
... grant support, investigators at Nationwide Children,s Hospital plan to ... leads to the development of a devastating brain tumor, ... Center for Childhood Cancer at The Research Institute at ... the Matthew Larson Foundation for this research. ...
... 1 (HealthDay News) -- Screening college athletes for heart conditions ... sudden cardiac death, according to a new study. ... heart abnormality or symptoms that required further screening, prompting researchers ... in sports. Every year in the United States, 60 ...
... Gardner HealthDay Reporter , WEDNESDAY, June 1 ... researchers were able to find previously undetected changes in ... had been diagnosed with mild brain injuries sustained from ... "absolutely not there yet," Christine Mac Donald, lead author ...
... a newer, more precise form of radiation therapy, ... hormone therapy than using three-dimensional radiation therapy, according ... of the International Journal of Radiation OncologyBiologyPhysics ... Society for Radiation Oncology (ASTRO). Three-dimensional radiation ...
... -- Newly diagnosed cancer patients frequently face hurdles in ... to new research from the Perelman School of Medicine ... Saturday, June 4 at the 2011 annual meeting of ... with private health insurance had difficulty scheduling an appointment, ...
... MAYWOOD, Ill. -- Baseline concussion tests given to hundreds ... some cases, according to a Loyola University Health System ... rate, meaning a test shows an athlete has recovered, ... cognitive impairments from the concussion. This could increase risks ...
Cached Medicine News:Health News:New grant to study how pediatric brain tumor, ependymoma, develops 2Health News: Experts Recommend Cardiac Screening for College Athletes 2Health News:Hi-Tech Scan Detects Soldiers' Head Injuries 2Health News:Hi-Tech Scan Detects Soldiers' Head Injuries 3Health News:Two-thirds of newly diagnosed cancer patients unable to obtain oncology appointments 2Health News:Does baseline concussion testing really reduce risks to athletes? 2
(Date:1/23/2015)... LOS ANGELES , Jan. 23, 2015 A lot ... the best methods for treating  certain illnesses, injuries, or conditions. ... to replace previous treatment methods with ones that they consider ... treating hernias, there is not one textbook method of treatment ...
(Date:1/23/2015)...  MedScope ( www.medscope.org ), the leading provider of medical ... Connected World magazine Connected World Award for its ... be used anywhere, anytime. The nomination was made by ... nominating MedScope, Landon Garner , Director of Marketing ...
(Date:1/23/2015)... Fla. , Jan. 23, 2015  HyGreen, Inc., a ... agreement and partnership with RCA Medical, a subsidiary of ... . Each year, hundreds of millions ... care-associated infections as organisms are transmitted from patient to ...
Breaking Medicine Technology:No One-Size-Fits-All Remedy for Hernia Correction 2MedScope Nominated by RacoWireless for Prestigious 2015 Connected World Magazine Connected World Award 2HyGreen Partners with RCA Medical in Johannesburg, South Africa 2
... Ill., April 19, 2011 Sysmex, a global ... systems technology, announced today an amended distributorship agreement ... automatically renews for up to four successive one-year ... including the Sysmex pocH-100 i™ , Sysmex KX-21N™, ...
... Premier Research Group Limited announces the re-branding of ... Research Company. With the continued growth in clinical development ... the medical device industry, Premier Research recognises this sector ... D-TARGET was founded in 1997 and acquired ...
Cached Medicine Technology:Sysmex America Signs Distributorship Agreement With LABSCO 2Premier Research Re-brands its Medical Device Business Unit to D-TARGET 2
4 mm wide tip....
Double-ended. Blunt and semi sharp 5 mm tips. Designated most popular model or size....
Double-ended. Designated most popular model or size....
Designated most popular model or size. Double-ended. 2 mm wide....
Medicine Products: