Navigation Links
Novel autoantibodies identified in patients with necrotizing myopathy
Date:8/19/2010

Researchers at Johns Hopkins University School of Medicine have identified a subgroup of patients with necrotizing myopathy who have a novel autoantibody specificity that makes them potential candidates for immunosuppressive therapy. The complete study is published in the September issue of Arthritis & Rheumatism, a journal of the American College of Rheumatology.

Myopathy is a term used to describe muscle disease. The National Institute of Neurological Disorders and Stroke (NINDS) defines the inflammatory myopathies as a group of diseases that involve chronic muscle inflammation, accompanied by muscle weakness. The chronic inflammatory myopathies are idiopathic, meaning they have no known cause. They are thought to be autoimmune disorders, in which the body's white blood cells (that normally fight disease) attack blood vessels, normal muscle fibers, and connective tissue in organs, bones, and joints.

Distinguishing between immune-mediated myopathies and other necrotizing myopathies such as muscular dystrophies and self-limited toxic myopathies is crucial because only autoimmune muscle diseases respond to immunosuppressive therapy. Unfortunately, clinical evaluation and diagnostic tests sometimes fail to determine whether a necrotizing myopathy is immune mediated, resulting in undertreatment of autoimmune myopathies or inappropriate immunosuppression in patients who do not have an immune-mediated disease.

In this study, muscle biopsy specimens and serum samples were evaluated for 225 patients with myopathy who were enrolled in a longitudinal study from March 2007 through December 2008. Myopathy was defined by muscle weakness, elevated creatine kinase (CK) levels, myopathic EMG findings, muscle edema on MRI, and/or features of myopathy on muscle biopsy.

The researchers identified 26 patients with necrotizing myopathies of unclear origin. Blood samples from these patients were screened for the presence of novel autoa
'/>"/>

Contact: Dawn Peters
healthnews@wiley.com
781-388-8408
Wiley-Blackwell
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Novel role: EZH2 boosts creation of ovarian cancer blood vessels
2. FSU study takes novel approach to understanding pituitary function
3. OU researcher developing novel therapy for Alzheimers disease
4. Vitamin B3 as a novel approach to treat fungal infections
5. Announcing: Intrinsic Imaging : Radiology Experts Launch Novel Medical Imaging CRO for Clinical Trials
6. Novel approaches to R&D in Africa needed
7. Novel radiotracer shines new light on the brains of Alzheimers disease patients
8. Team led by LA BioMed scientist develops novel approach to study neurological disorders
9. Novel paclitaxel formulation encouraging for treating advanced lung cancer
10. Novel Drug Combats Advanced Melanoma
11. Novel RNA interference screening technique identifies possible path for malignant glioma treatment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/1/2014)... D.C. and ATLANTA (PRWEB) October 01, 2014 ... information security executive networking and relationship-marketing firm, ... 2014 Information Security Executive® and Project of ... include top-ranking decision makers representing organizations in ... academics. Projects include large-scale technology endeavors that ...
(Date:10/1/2014)... (PRWEB) October 01, 2014 Beverly Hills ... Kathleen Mojas is celebrating 20 years of private practice ... hundreds of people to achieve greater joy and fulfillment ... list of warning signs and suggestions for anyone who ... Mojas explains: “Believe it or not, it’s not ...
(Date:10/1/2014)... Inc., announced today their new NoteSwift™ 2.0 for Allscripts ... the bridge between the EHR and Dragon Medical interpreting ... at the point of care. NoteSwift reduces the time ... than half – and virtually eliminates mouse clicks – ... EHR use according to the June 12, 2014 HIMSS ...
(Date:10/1/2014)... the occasion of the Leishmaniasis East Africa Platform ... international leishmaniasis experts, results of a pharmacovigilance ... plan, carried out by MSF, DNDi, and national ... presented to key decision makers in order to ... the combination of Sodium Stibogluconate and Paromomycin (SSG&PM) ...
(Date:10/1/2014)... 01, 2014 Dr. Saj Jivraj, one ... prosthodontists, is traveling to Chennai, India, tomorrow to speak ... 2 and 3. , Dr. Jivraj is founder of ... Oxnard, Calif., and one of the world’s foremost prosthodontists, ... replacement. He is speaking to the Indian Society of ...
Breaking Medicine News(10 mins):Health News:T.E.N. Announces Nominees for the 2014 ISE® North America Awards; People’s Choice Award voting now open to industry at large 2Health News:T.E.N. Announces Nominees for the 2014 ISE® North America Awards; People’s Choice Award voting now open to industry at large 3Health News:T.E.N. Announces Nominees for the 2014 ISE® North America Awards; People’s Choice Award voting now open to industry at large 4Health News:T.E.N. Announces Nominees for the 2014 ISE® North America Awards; People’s Choice Award voting now open to industry at large 5Health News:T.E.N. Announces Nominees for the 2014 ISE® North America Awards; People’s Choice Award voting now open to industry at large 6Health News:T.E.N. Announces Nominees for the 2014 ISE® North America Awards; People’s Choice Award voting now open to industry at large 7Health News:Prominent Beverly Hills Psychologist Dr. Kathleen Mojas Celebrating 20 Years in Private Practice Identifies Common Warning Signs That You May Be In a Toxic Relationship. 2Health News:Prominent Beverly Hills Psychologist Dr. Kathleen Mojas Celebrating 20 Years in Private Practice Identifies Common Warning Signs That You May Be In a Toxic Relationship. 3Health News:NoteSwift Joins Allscripts Developer Program 2Health News:NoteSwift Joins Allscripts Developer Program 3Health News:Results of large-scale roll out of combination treatment for kala-azar in Eastern Africa 2Health News:One of Woodland Hills’ Top Cosmetic Dentists Speaking to Indian Society of Oral Implantologists Tomorrow 2Health News:One of Woodland Hills’ Top Cosmetic Dentists Speaking to Indian Society of Oral Implantologists Tomorrow 3Health News:One of Woodland Hills’ Top Cosmetic Dentists Speaking to Indian Society of Oral Implantologists Tomorrow 4Health News:One of Woodland Hills’ Top Cosmetic Dentists Speaking to Indian Society of Oral Implantologists Tomorrow 5
... scientists assumed that the adult heart is unable to ... Center for Molecular Medicine (MDC) Berlin-Buch and the Charit ... that this dogma no longer holds true. Dr. Laura ... able to show that the body`s own heart muscle ...
... Free Bench-Top Flow Cytometer System Twice Yearly to Support Innovative ... , -Learn More about the Revolutionary ... Biology Annual Meeting- , , ... life sciences company developing revolutionary bench-top flow cytometer systems, today ...
... LLP today announced,that, effective January 1, 2009, it ... and regulation practice. MARC Associates are experts in ... distinguished client base.,Other areas of expertise include energy ... "We have been ...
... age of 100 and never looking a day over 60 is now ... now, this information is available to everyone absolutely free. , ... ... Health News Report is offering a free download to the popular book ...
... hemodynamic monitor (IHM) may help to guide medical treatment ... with diastolic heart failure (DHF), reports a study in ... http://www.onlinejcf.com/ ), published by Elsevier. , Led by Michael ... Charleston, the researchers analyzed data on DHF patients enrolled ...
... Dec. 11 Perot Systems Corporation,(NYSE: ... the Daughters,of Charity Health System (DCHS) has awarded ... Under terms of the agreement, Perot Systems will ... application implementation and,support, desktop support, local and wide ...
Cached Medicine News:Health News:Heart regenerates after infarction -- first trials with mice 2Health News:Researcher Receives Free Flow Cytometer System as First Winner of Accuri(R) Flow Cytometer Creativity Awards Program 2Health News:Researcher Receives Free Flow Cytometer System as First Winner of Accuri(R) Flow Cytometer Creativity Awards Program 3Health News:Researcher Receives Free Flow Cytometer System as First Winner of Accuri(R) Flow Cytometer Creativity Awards Program 4Health News:Holland & Knight Welcomes MARC Associates - Experts in Health Care and Intergovernmental Policy - to the Firm's Public Policy & Regulation Practice 2Health News:Holland & Knight Welcomes MARC Associates - Experts in Health Care and Intergovernmental Policy - to the Firm's Public Policy & Regulation Practice 3Health News:Holland & Knight Welcomes MARC Associates - Experts in Health Care and Intergovernmental Policy - to the Firm's Public Policy & Regulation Practice 4Health News: Anti-Aging Miracle Physicians Have Been Waiting for is Finally Here : Free Book Available From Natural Health News Report Reveals the Secret to Staying Young 2Health News:Implantable monitor may help in managing diastolic heart failure 2Health News:Perot Systems Awarded Contract Extension By Daughters of Charity 2Health News:Perot Systems Awarded Contract Extension By Daughters of Charity 3
(Date:9/30/2014)...  According to their CEO, Rob Bohacs ... is going through a complete transformation with highly ... the current clinical trial management process isn,t configured ... trials, which will ultimately drive the prescription cancer ... has been recognized by the National Cancer Institute as ...
(Date:9/30/2014)... 30, 2014  Alimera Sciences, Inc. (NASDAQ: ... the research, development and commercialization of prescription ophthalmic pharmaceuticals, ... advance from Hercules Technology Growth Capital, Inc. (NYSE: ... and final advance under the Loan and Security Agreement ... , Alimera Sciences Limited, entered into with Hercules ...
(Date:9/30/2014)... -- A study using a relatively new imaging tool, ... the composition of carotid artery disease and has the ... disease, a leading cause of stroke. ... 2010 and May 2012, was featured in the June ... College of Cardiology (JACC) Cardiovascular Interventions. Interventional cardiologist ...
Breaking Medicine Technology:Small Denver Company Pharmatech driving a large revolution in how cancer clinical trials are managed 2Alimera Sciences Receives $25 Million Advance from Hercules Technology Growth Capital 2New Imaging Tool May Allow Tailoring of Stroke Prevention to Each Patient 2
... 21, 2012 InterMune, Inc. (NASDAQ: ITMN ... agreement with Vidara Therapeutics International Limited (Vidara) to sell ... transaction valued at $55 million plus a two-year royalty ... group of companies with operations in Ireland and the ...
... 2012  Consumers Union, the policy and advocacy arm of Consumer Reports, ... patients at risk in a full-page print ad in ... vote on a bill this week to reauthorize the statute governing ... that the FDA does not have the power under current law ...
Cached Medicine Technology:InterMune to Divest Actimmune® (Interferon Gamma-1b) 2InterMune to Divest Actimmune® (Interferon Gamma-1b) 3Dangerous Medical Device Loophole Puts Patients At Risk 2Dangerous Medical Device Loophole Puts Patients At Risk 3
This standard tying forcep is curved with 5mm titanium coated platforms. Length 85 mm....
Catalano curved tying forcep has 6 mm V-grove tying platform. Overall length 100 mm....
Kelman - McPherson tying forceps with serrated handle, platform 4 mm and overall length of 85 mm....
Troutman tying forceps are curved, delicate, bullet shape, with tying platforms. Flat pattern. Ultra fine platforms ideal for 10-0 or 11-0 suture material. Platforms fully meet to hold suture firmly....
Medicine Products: