Navigation Links
Novel analysis method organizes genomic cancer data
Date:6/30/2011

The technology that allows scientists to profile the entire genome of individual tumors offers new hope for discovering ways to select the best treatment for each patient's particular type of cancer. However, these profiles produce huge amounts of data, and the volume alone creates unique analytical problems.

In a study published on-line this week in the journal BMC Medical Genomics, researchers from Huntsman Cancer Institute (HCI) at the University of Utah describe a new analytical approach based on a concept called multiplicity, that can organize large amounts of varied genetic data. The method allows researchers to create three-dimensional models revealing previously unknown relationships among the genes involved with different types of cancer.

"This technique shows similar genetic profiles for different types of cancers, which could open the door to trials of already approved drugs for additional cancers," said Lewis Frey, PhD, assistant professor in the Department of Biomedical Informatics and an HCI investigator. "It can bring to light previously unknown genetic connections between different cancers, helping focus the search for cancer-causing genetic mutations. It makes whole genome data more usable for both clinical and laboratory researchers."

Stephen R. Piccolo, Ph.D., a postdoctoral research associate in the Department of Biomedical Informatics at the University of Utah, and Mary E. Edgerton, M.D., Ph.D., associate professor in the Department of Pathology at MD Anderson Cancer Center in Houston, Texas, are co-authors of the article. The study was funded in part by an Incentive Seed Grant from the University of Utah, and a National Library of Medicine training grant.


'/>"/>

Contact: Linda Aagard
801-587-7639
University of Utah
Source:Eurekalert

Page: 1

Related medicine news :

1. Scientists identify a novel mechanism for evolution of highly aggressive cancers
2. CSHL structural biologists reveal novel drug binding site in NMDA receptor subunit
3. HIV-infected donors present novel source of organs for HIV-infected transplant candidates
4. Study identifies novel role for a protein that could lead to new treatments for rheumatoid arthritis
5. GEN reports on novel noninvasive tests for early cancer detection
6. Novel program is saving newborns’ lives in developing countries
7. Novel Hepatitis C Drug Holds Promise: FDA
8. A potential novel drug-target for colorectal cancer treatment comes from the brain
9. Researchers identify novel pathophysiologic mechanism responsible for autoimmunity
10. Novel association between Parkinsons disease and prostate cancer
11. Novel immunotherapy drug receives FDA approval for the treatment of metastatic melanoma
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/6/2016)... ... May 06, 2016 , ... DrugDev President ... the way the pharmaceutical industry conducts clinical trials. This month Ibs was named No. ... in pharma, and he was honored as a Tech Disruptor by the Philadelphia Business ...
(Date:5/6/2016)... ... May 06, 2016 , ... ... Service, their latest implementation service offering for global clients of Coupa ( Coupa ... , Bluvault’s Integration Service is a key component in the suite of ...
(Date:5/6/2016)... (PRWEB) , ... May 06, 2016 , ... From May ... Chicago, IL, offering EarQ members the unique opportunity to learn more about Signia’s technology ... independent practice growth. , “It is our priority to see practices succeed in this ...
(Date:5/6/2016)... ... 2016 , ... Multiple award winning plumbing company in San Diego, ... Maintaining core values of exceptional customer service, quality work at reasonable rates, and giving ... in San Diego plumbing, and other services including heating & air conditioning and restoration ...
(Date:5/6/2016)... LA (PRWEB) , ... May 06, 2016 , ... ... Health System and David Konur, CEO of Cardiovascular Institute of the South announced ... will be performing a live case of an Intravascular Ultrasound Guided Coronary Atherectomy. ...
Breaking Medicine News(10 mins):
(Date:5/5/2016)... 2016  Replikins Ltd. today reported initial promising results in animal trials of its ... http://photos.prnewswire.com/prnh/20160505/364345 ... ... ... specimens recorded on Pubmed. The analysis identified the highest gene Replikin Counts in Zika ...
(Date:5/5/2016)... , May 5, 2016  Diagnostic imaging has ... due to concerns that these tests cause health care costs ... to imaging, as well as the adoption of ... of medical peripherals that help health care providers cut costs, ...  advanced medical imaging is a renowned authorized reseller of ...
(Date:5/5/2016)... 2016 Research and ... Thalassaemia Market and Competitive Landscape Highlights - ...      (Logo: http://photos.prnewswire.com/prnh/20160330/349511LOGO ) ... Competitive Landscape Highlights - 2016, provides comprehensive ... Thalassaemia market valuations and forecast, Thalassaemia products ...
Breaking Medicine Technology: