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Novel Vaccine Approach to Human Cytomegalovirus Found Effective Says UC Davis Study
Date:9/17/2013

Sacramento, PA (PRWEB) September 17, 2013

An experimental vaccine against human cytomegalovirus (CMV) infection, which endangers the developing fetus, organ transplant recipients, patients with HIV and others who have a weakened immune system, proved safe and more effective than previous vaccines developed to prevent infection by the ubiquitous virus.

The first-of-its-kind approach to preventing human CMV infection, developed by a team of scientists at UC Davis and the University of Alabama, Birmingham, induced broader immunological protection in an animal model. The research study will appear in the November issue of the Journal of Virology.

Development of a CMV vaccine has been ranked as the highest priority by the Institute of Medicine, an independent agency of the National Academy of Science, because of “the lives it would save and the disabilities it would prevent,” according to the CDC.

"We’ve completed the first step in developing a vaccine to protect people against CMV by interfering with the virus’s attempts to enter and infect cells in the body,” said Peter A. Barry, a professor of pathology and laboratory medicine at the UC Davis School of Medicine and lead author of the study. Barry also is a member of the faculty at the Center for Comparative Medicine and a staff scientist at the California National Primate Research Center at UC Davis.

About CMV

CMV is a type of herpes virus that is spread through close contact with the saliva, urine or other body fluids of a person infected with the virus. Most CMV infections are not diagnosed because the virus typically causes few, if any, symptoms. As a result, most people infected with CMV are unaware that they harbor the virus — a condition that is of most concern among pregnant women, who are at risk for transmitting the virus to the fetus. Children who are congenitally infected with CMV may have cognitive and other development
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