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Novel Photoconductive Cellular Depolarization Technology Reveals Insight Into Neuronal Growth, Guidance, and Regeneration
Date:1/30/2009

growth guidance both spatial and temporal is mediated by neuronal activity. Further under experimental conditions simulating injury, it was observed that growth cone attraction was not inhibited suggesting that this mechanism could be used to guide neuronal regeneration following axonal injury.

Photoconductive stimulation has enabled researchers to significantly expand the depth, breadth, and complexity of approaches aimed at understanding and addressing areas of unmet neurological healthcare need. This novel technology provides researchers with the means to dynamically study excitation dependent cellular responses without the requirement for a direct physical link to the cell (such as with electrodes in patch clamping or transistor contact necessary in micro electrode arrays). The PSD can also be used in place of pharmacological agonist stimulation, which does not allow for specific cell targeting and/or rapid repetitive depolarization.

About Neurosilicon

Neurosilicon develops novel brain-computing interfaces to expand the scientific understanding of the human brain and to revolutionize and improve the effectiveness of drug discovery. The company's flagship product, the Photoconductive Stimulation Device (PSD) stimulates excitable cells in a precise and controllable fashion. Neurosilicon is comprised of a multidisciplinary team of neuroscientists and engineers working together to advance the boundaries of life science research.

For more information on the (PSD), or to order, please visit http://www.neurosilicon.com


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