Navigation Links
Novel DNA sequencer for MDC's systems biology
Date:7/15/2011

The Berlin Institute for Medical Systems Biology (BIMSB) of the Max Delbrck Center for Molecular Medicine (MDC) in Berlin, Germany, will be the first academic research institution in Continental Europe to acquire a novel DNA sequencer enabling the sequencing of single DNA molecules in real time. The SMRT (single molecule, real-time) technology is also faster than current high-throughput technologies. The researchers of the BIMSB will use this third-generation sequencing technology, which was launched on the market in April 2011 by Pacific Biosciences, Menlo Park, California, USA, to gain deeper insight into gene regulation. The new sequencer, PacBio RS, will be installed in the BIMSB labs early in September.

To develop the "single molecule real-time" (SMRT) technology, Pacific Biosciences has combined nanotechnology, biochemistry, surface chemistry and optics. The new sequencer determines DNA sequences in real time by visualizing the reaction of a single enzyme with a single DNA molecule. The process does not require DNA amplification before the sequencing reaction and therefore avoids potential bias. The system is able to produce average DNA reads of greater than 1000 bases and accomplishes one experiment in one day instead of one week or longer. The PacBio RS perfectly complements the current scientific applications and capacities of next-generation sequencing technologies of the BIMSB Scientific Genomics Platform led by Wei Chen.

"The outstanding characteristic of SMRT technology is not only that you can watch how DNA is being synthesized, but also that it enables us to quantitatively determine gene regulation, RNA function, epigenetic gene regulation, DNA modification and genome structure. It allows us to look deeper into how genes and regulatory networks function and opens new approaches to personalized medicine," said Walter Rosenthal, scientific director of the MDC, and Nikolaus Rajewsky, head of the Berlin Institute for Medical Syste
'/>"/>

Contact: Barbara Bachtler
bachtler@mdc-berlin.de
49-309-406-3896
Helmholtz Association of German Research Centres
Source:Eurekalert

Page: 1 2

Related medicine news :

1. NIH grants to Childrens Hospital will advance novel stem cell treatments for blood disorders
2. A novel in vitro model for light-induced wound healing
3. Novel program translates behavioral and social science research into treatments to reduce obesity
4. Reovirus may be a novel approach to prostate cancer treatment
5. Novel stroke treatment passes safety stage of UCI-led clinical trial
6. Novel medical home program for pediatric patients, families cuts ER visits in half
7. MessageSolution First in the Market to Offer All-in-One, Integrated Cloud-Based Archiving for Email, File Systems and SharePoint at Novell BrainShare 2010
8. Novel Parkinson's Treatment Strategy Involves Cell Transplantation
9. Novel Method Eyed for Normalizing Blood Sugar
10. Novel soy germ-based dietary supplement, SE5-OH containing natural S-Equol, examined for safety and influence on hormones in pre- and post-menopausal women
11. Novel nanoparticles prevent radiation damage
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/19/2014)... a well-known bamboo product manufacturer and retailer, has unveiled its ... is excited to reveal the new items, and it has ... Now, every customer can get a discounted price, up to ... , The company’s deckings are made of the finest ... They are perfect for a dining room, living room, kitchen, ...
(Date:8/19/2014)... in Houston, Texas, is pleased to announce it is now ... with old fillings that need replacing, will benefit from the ... teeth. , From now on any cavities will be repaired ... amalgam free. Even though amalgam fillings have been deemed as ... children over the age of six, they do contain mercury ...
(Date:8/19/2014)... Wood River, Il (PRWEB) August 20, 2014 ... of the allopathic medical world that chiropractic adjustments are ... artery dissection, and this is why they do not ... and the more educated medical doctors do refer to ... the truth. However a statement regarding new research has ...
(Date:8/19/2014)... (PRWEB) August 20, 2014 Crosley Law Firm, ... involving hand amputation against Lone Star Bakery for an undisclosed ... injured in March and May of 2011, respectively. The injuries ... and resulted in severe injury to the left hand of ... accidents, Lone Star Bakery was short-staffed, having lost 200 of ...
(Date:8/19/2014)... August 20, 2014 What gives skin an ... can soften skin, replenish and nourish it while lightly exfoliating? ... , "Client after client raves about how their skin feels ... founder of Sublime Beauty®. "The ingredients are very rich ... Simply smooth it over cleansed skin of the face ...
Breaking Medicine News(10 mins):Health News:Promotional Bamboo Deckings from Well-known Online Supplier BambooIndustry.com 2Health News:Midtown Dentistry Announces It Is Now an Amalgam-Free Office 2Health News:Is It True That the Chiropractor Can Cause a Stroke? Dr. Harbison of AlignLife Wood River Speaks Up 2Health News:Is It True That the Chiropractor Can Cause a Stroke? Dr. Harbison of AlignLife Wood River Speaks Up 3Health News:Is It True That the Chiropractor Can Cause a Stroke? Dr. Harbison of AlignLife Wood River Speaks Up 4Health News:Crosley Law Firm Reaches Settlement for Hand Amputation Victims at Commercial Bakery 2Health News:That "Something Special" to Improve Skin Takes Only 10 Minutes Per Week; on Sale at Sublime Beauty® 2
... park is more than just a nice way to ... health, according to University of Illinois environment and behavior ... advocates, landscape architects, and popular writers have consistently claimed ... recently, their claims haven,t undergone rigorous scientific assessment." ...
... California, San Diego School of Medicine say antibodies to ... be useful as a future biomarker for predicting cancer ... concentration, used as a treatment for suppressing tumor growth. ... MD, assistant clinical professor of medicine, and Ajit Varki, ...
... News) -- Motorcycle deaths in the United States fell by about ... row fatalities have declined, according to a new report. The ... accidents in 2010 than in 2009, according to a report released ... estimated 4,465 were killed in 2009 compared to 4,376 in 2010. ...
... prohibition against testosterone therapy in men with untreated or ... study published in The Journal of Urology . ... a history of prostate cancer, even if treated and ... to the belief that testosterone activated prostate cancer growth, ...
... Translational Behavioral Medicine: Practice, Policy, Research (TBM), ... The journal will debut with a special section, ... Behavioral Medicine is an international, peer-reviewed journal ... is to engage, inform, and catalyze dialogue among ...
... study published in The American Journal on Addictions ... have high rates of substance use disorders. , Led by ... used national administrative data from the Department of Veterans Affairs ... served in Iraq and Afghanistan who were also diagnosed with ...
Cached Medicine News:Health News:Green environments essential for human health 2Health News:Green environments essential for human health 3Health News:Green environments essential for human health 4Health News:A cancer marker and treatment in 1? 2Health News:A cancer marker and treatment in 1? 3Health News:Motorcycle Deaths Drop for Second Straight Year: Report 2Health News:Study suggests another look at testosterone-prostate cancer link 2Health News:Study suggests another look at testosterone-prostate cancer link 3Health News:Springer launches new journal, Translational Behavioral Medicine: Practice, Policy, Research 2
(Date:8/19/2014)... 19, 2014   Lincor Inc. today ... technology to New Jersey -based ... CarePoint Health will deploy Lincor,s PatientLINC technology across ... Hospital and Hoboken University Medical Center. ... software solutions to help hospitals reach new levels ...
(Date:8/19/2014)...  The Alabama Supreme Court, in a 6-3 decision on ... who mislead doctors into believing that prescription medicines the companies ... v. Wyeth, and the decision came after the Supreme Court ... year. Heninger Garrison Davis attorneys Lew Garrison and ... Danny Weeks . The decision won a ...
(Date:8/19/2014)... , Aug. 19, 2014 Talyst, a market ... exhibiting at the 2014 NPPA Summer Conference in ... be showcasing its 340B software products and services.   ... splitting solutions, supplying over 400 customers with a variety ... 340B solutions including its latest solution, AutoSplit® Contract Pharmacy ...
Breaking Medicine Technology:Lincor Announces Agreement With CarePoint Health For State-Of-The-Art Patient Engagement Technology 2Heninger Garrison Davis Clients To Get Their Day in Court Against Brand Drug Companies 2Heninger Garrison Davis Clients To Get Their Day in Court Against Brand Drug Companies 3Heninger Garrison Davis Clients To Get Their Day in Court Against Brand Drug Companies 4Talyst Exhibits at the NPPA Summer Conference 2
... mechanism for speed, stability and durability. ... display modes, multiple units of measure, ... auto print, and GLP/GMP/ISO output including ... clock. Built-in, motor-driven internal calibration ...
... - Battery Powered (6 size AA required). ... (g, ct, oz, ozt, GN, dwt, mom, ... and Percent Measure functions, Auto Print. Optional ... AC adapter may be ordered for AC ...
60 month warranty, constructed entirely of aluminum alloy, allows the selection of 11 units of measure....
60 month warranty, constructed entirely of aluminum alloy, allows the selection of 11 units of measure....
Medicine Products: