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Novavax Reports Fourth Quarter and 2008 Year-End Financial Results
Date:3/31/2009

g Cadila's world-class research, clinical development, and manufacturing expertise and infrastructure to support development of current and future vaccine candidates through a $7.5 million service contract spanning the next three years.

  • The Company achieved additional favorable results from the second stage of a Phase IIa clinical trial of its pandemic flu VLP vaccine candidate. As reported previously, the vaccine demonstrated strong neutralizing antibody titers across all three doses tested, exhibiting increasing antibody titers with the escalation of the dose. The new data showed that the vaccine also induced strong hemagglutination inhibition ("HAI") responses and was well tolerated with no reports of serious adverse events.
  • The Company announced favorable safety and immunogenicity results in December 2008 from its Phase IIa seasonal flu VLP vaccine dose-ranging study that started in September 2008. The Phase IIa randomized, placebo controlled clinical trial evaluated the safety and immunogenicity of different doses of its trivalent seasonal flu VLP vaccine in healthy adults, who received a single injection of either a placebo or a VLP vaccine dose of 5 mcg, 15 mcg or 30 mcg per strain.
  • The Company announced favorable results from a preclinical study, conducted in collaboration with the University of Massachusetts, evaluating the immunogenicity and efficacy of a Respiratory Syncitial Virus ("RSV") vaccine candidate in mice directed against the surface glycoprotein (or "G" protein). The vaccine induced strong antibody responses against RSV and protected mice against RSV replication in the lungs on challenge.
  • The Company announced favorable results from a preclinical study in mice evaluating an RSV vaccine directed against the viral fusion ("F") protein, which fuses with cells in the respiratory tract and causes illness.'/>"/>

SOURCE Novavax, Inc.
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