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NovaBay's Aganocides Show Penetration and Efficacy in a Pre-Clinical Infected Human Nail Model of Onychomycosis
Date:10/30/2009

Ph.D., chairman and chief executive officer of NovaBay. "We are encouraged by these preclinical results, especially given the rigor of the MedPharm model and its established and predictive value."

In this model, developed and conducted by MedPharm LTD, Surrey, United Kingdom, formulations of both NVC-422 and NVC-612 were highly effective against Trichophyton rubrum, the fungus commonly found in nail infections and normally very difficult to eradicate. A laboratory-cultured clinical isolate of T. rubrum was used to infect full thickness sterile human nails in specially constructed cells. After 14-days of incubation, single applications of the Aganocide formulations were applied to the nail surface opposite from the infected side. After seven more days of incubation, the nails were analyzed for the presence of adenosine triphosphate (ATP) as a measure of fungal viability. Uninfected nails, infected untreated nails and placebo treated nails were used as controls.

Conference Call and Webcast Information

NovaBay will host an investor webcast and conference call to discuss the onychomycosis data.

    Date/time of live call: Friday October 30, 2009, 10:00 AM eastern time
    US/Canada dial-in: (877) 862-4241 / international dial-in: (281) 312-0948
    US/Canada replay: (800) 642-1687 / international replay: (706) 645-9291
    Passcode for live and archived conference call is 37797881

For the live and archived webcast, please visit the Investor Events page on the NovaBay website at www.novabaypharma.com. The webcast will be archived for 90 days and the telephone replay for seven days.

About Onychomycosis

Onychomycosis is the infection of the nail plate/bed by a fungus. Although onychomycosis is considered a cosmetic condition, it can cause acute pain while the physical
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SOURCE NovaBay Pharmaceuticals, Inc.
Copyright©2009 PR Newswire.
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