Navigation Links
NovaBay's Aganocides Show Penetration and Efficacy in a Pre-Clinical Infected Human Nail Model of Onychomycosis
Date:10/30/2009

EMERYVILLE, Calif., Oct. 30 /PRNewswire-FirstCall/ -- NovaBay Pharmaceuticals, Inc. (NYSE-Amex: NBY) today announced that its Aganocide® compounds demonstrate potent antifungal activity in an established pre-clinical infected nail model of onychomycosis. The study data will be presented tomorrow at the 47th Annual Meeting of the Infectious Diseases Society of America (IDSA) in Philadelphia.

"This model tests both the penetration of the nail as well as the effectiveness of the compounds against the targeted fungus. What is remarkable is that, after treatment, the Aganocide formulations were able to eradicate the fungi grown on the other side of the nail, hence indicating not only good penetration but a good antifungal activity against T. rubrum, the fungus responsible for onychomycosis commonly known as nail infection," said Dr. Behzad Khosrovi, senior vice president of product development at NovaBay. "Nail fungus is notoriously difficult to treat predominantly due to the inability of many topical antifungal drugs to penetrate the nail, a hurdle we were able to overcome due to the proprietary characteristics of our compounds."

The study "In Vitro Evaluation of Stable Derivatives of the Chlorotaurines( )on Infected Human Nail Model as Potent Antifungal Agents for the Treatment of Onychomycosis" tested formulations of both N,N-dichloro-2,2-dimethyltaurine (NVC-422) and N-chloro-2,2-dimethyltaurine (NVC-612), both proprietary NovaBay compounds, which are stable derivatives of endogenous chlorotaurines that possess potent and rapid antimicrobial activity against a wide range of pathogens. The endogenous chlorotaurines play an important role in mammalian innate immunity to invading pathogens.

"Onychomycosis represents a significant market opportunity for any topical agent," said Ron Najafi,
'/>"/>

SOURCE NovaBay Pharmaceuticals, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine news :

1. Frost & Sullivan Awards Agfa Healthcare for Brazilian Market Penetration Leadership in 2009
2. Milestone Scientific Expands Global Sales Strategy to Enhance Penetration of International Dental Markets
3. Premature ejaculation spray enables men to last 6 times longer after penetration
4. Lumension Security Receives Frost & Sullivan 2008 Global Market Penetration Leadership Award
5. OmniGuide(R) Secures $25 Million in Funding to Support Continued Growth and New Market Penetration
6. Orexigen(R) Therapeutics Phase 2b Trial for Empatic(TM) Meets Primary Efficacy Endpoint Demonstrating Significantly Greater Weight Loss Versus Comparators in Obese Patients
7. LIVALO(R) Demonstrates Sustained, Long-Term Efficacy and Tolerability in Patients With Primary Hypercholesterolemia or Mixed Dyslipidemia
8. Advanced Life Sciences Restanza Demonstrates Efficacy in Treating Anthrax Infection
9. 96-Week Safety and Efficacy Findings Presented for INTELENCE(TM) (etravirine) As Part of HIV Combination Therapy
10. -Contrave(R) Obesity Research Phase 3 Program Meets Co-Primary and Key Secondary Endpoints; Exceeds FDA Efficacy Benchmark for Obesity Treatments-
11. Econiche(TM) Vaccine Efficacy Summarized in July Issue of Foodborne Pathogens and Disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... The Capital Institute for Neurosciences at Capital Health ... a clinical trial that delivers chemotherapy to brain tumors ... the procedure, done at Capital Health Medical Center – ... tiny catheter through the patient’s femoral artery in the ... the brain. Once the catheter reached the brain, chemotherapy ...
(Date:7/10/2014)... Colorado (PRWEB) July 10, 2014 ... will gather in Copenhagen this July 13-17 to ... bringing the world closer to breakthroughs in dementia ... the world’s largest conference of its kind. , ... AAIC serves as a catalyst for generating new ...
(Date:7/10/2014)... 10, 2014 In his latest blog ... drug treatment facility CEO Per Wickstrom has listed 5 ... trying to confirm an appointment, get information or sometimes ... following-up without being annoying is a skill that most ... a way to keep the dialogue moving without coming ...
(Date:7/10/2014)... (July 8, 2014) A new study from Colorado ... improvements, poor oral health remains a major problem in ... "The oral health among Native Americans is abysmal with ... of the country," said Terrence Batliner, DDS, MBA, associate ... at the School of Public Health. "The number one ...
(Date:7/10/2014)... THURSDAY, July 10, 2014 (HealthDay News) -- Teens who ... are more likely to develop emotional symptoms such as ... factors such as these that may exacerbate issues teens ... appropriate treatment and in making decisions about when to ... school for these athletes," study authors Lisa Koehl and ...
Breaking Medicine News(10 mins):Health News:New Trial Delivers Chemotherapy to Brain Tumor Through Artery in Leg 2Health News:New Trial Delivers Chemotherapy to Brain Tumor Through Artery in Leg 3Health News:Per Wickstrom’s Latest Blog Post Lists 5 Ways to Follow-up Without Being Annoying 2Health News:Study finds widespread oral health problems among Navajo 2Health News:Some Teens May Face Emotional Problems After Concussion 2
... 26 Velos, Inc., the recognized leader and ... and Net.Orange, Inc., the respected healthcare Internet solutions ... Cancer Research Centers (Mary Crowley). The two companies ... for strong central clinical research infrastructure and implementation ...
... Sandals(R) Originals2 Footwear by BeechHUNTINGTON BEACH, Calif., Feb. ... Yoga Sandals(R) Originals line with new adjustable ... This patented foot therapy can now be customized ... foot , increasing flexibility and helping improve balance ...
... LLC ( http://www.GlenwoodSystems.com ) launches the GlaceComplete product suite which seamlessly ... an assisted medical billing process. The product has been designed ... maximizing revenue contribution for the average office based medical practice. ... ...
... Today, AmeriGlide announced the recipient of this years AmeriGlide Achiever Scholarship. ... a wheelchair. , ... Raleigh, NC (PRWEB) February 26, ... of the first semi-annual AmeriGlide Achiever Scholarship. The AmeriGlide Achiever Scholarship ...
... Honored for Comebacks from Ostomy SurgeryWASHINGTON, Feb. 25 ... improving the lives of other ostomates, was named this ... pilot Robert (Bob) Cuyler was named the first recipient ... ceremony here this evening. Founded in 1984 by ...
... ArvinMeritor (NYSE: ARM ) today announced that ... by Lin Cummins, senior vice president of Communications for ArvinMeritor, ... one of the most challenging economic times in history, I ... and individuals to help wipe out heart disease, the number ...
Cached Medicine News:Health News:Mary Crowley Cancer Research Centers Achieve Dramatic Improvements in Financial Infrastructures With Velos eResearch and Net.Orange Systems 2Health News:Mary Crowley Cancer Research Centers Achieve Dramatic Improvements in Financial Infrastructures With Velos eResearch and Net.Orange Systems 3Health News:Mary Crowley Cancer Research Centers Achieve Dramatic Improvements in Financial Infrastructures With Velos eResearch and Net.Orange Systems 4Health News:Sandal Evolution(R) Takes a Healthy Step 2Health News:Glenwood Systems, LLC Improves Medical Billing Process with GlaceComplete 2Health News:Glenwood Systems, LLC Improves Medical Billing Process with GlaceComplete 3Health News:AmeriGlide Announces Recipient of AmeriGlide Achiever Scholarship 2Health News:Great Comebacks(R) Program Announces 2008 National Award Winner and Inaugural Tony Snow Public Service Award 2Health News:Great Comebacks(R) Program Announces 2008 National Award Winner and Inaugural Tony Snow Public Service Award 3Health News:Great Comebacks(R) Program Announces 2008 National Award Winner and Inaugural Tony Snow Public Service Award 4Health News:Great Comebacks(R) Program Announces 2008 National Award Winner and Inaugural Tony Snow Public Service Award 5Health News:Great Comebacks(R) Program Announces 2008 National Award Winner and Inaugural Tony Snow Public Service Award 6Health News:ArvinMeritor Proud to Sponsor American Heart Association Campaign 2
(Date:7/10/2014)... Mass. , July 10, 2014 Decision ... report awareness of the U.S. Food and Drug Administration,s ... new phosphate binder Velphoro, which was approved by the ... in chronic kidney disease (CKD) patients on dialysis. ... TreatmentTrends: Nephrology (US) Q2 2014 : ...
(Date:1/15/2014)... 15, 2014 Most osteoporosis patients want a choice ... online survey* sponsored by Mission Pharmacal Company. The survey, ... Foundation online support community, revealed that 74 percent of ... in a form other than a pill or a ...
(Date:1/15/2014)... Jan. 15, 2014 AARP Foundation today announced it has ... suffering from the severe cold weather that has gripped much ... helping those in need; so to support these emergency relief ... to $250,000, which could mean up to $500,000 in aid. ...
Breaking Medicine Technology:Half of Surveyed Nephrologists Report Moderate Familiarity with Velphoro, Which Received FDA Approval Late Last Year for the Treatment of Hyperphosphatemia in Dialysis 2Half of Surveyed Nephrologists Report Moderate Familiarity with Velphoro, Which Received FDA Approval Late Last Year for the Treatment of Hyperphosphatemia in Dialysis 3Mission Pharmacal Conducts Online Survey of Osteoporosis Patients 2Mission Pharmacal Conducts Online Survey of Osteoporosis Patients 3AARP Foundation Establishes Winter Relief Fund for Older Adults Suffering from the Severe Cold Weather 2AARP Foundation Establishes Winter Relief Fund for Older Adults Suffering from the Severe Cold Weather 3
... BIRMINGHAM, Ala., June 8, 2011 SANYO North ... its Cell Processing Work Station (CPWS), an integrated, stand-alone ... stem cell and cell therapies for research use, has ... (UAB) as the nation,s first installation of the CPWS, ...
... 2011 According to a report published today by ... has begun to adapt to stricter governmental brand name ... it files for every new drug. These newer standards ... European Medicines Agency (EMA) are part of an effort ...
Cached Medicine Technology:SANYO Installs First Cell Processing Work Station in the United States at University of Alabama at Birmingham 2SANYO Installs First Cell Processing Work Station in the United States at University of Alabama at Birmingham 3Thomson Reuters Trademark Report Reveals New Challenges and Opportunities for Pharmaceutical Brands 2Thomson Reuters Trademark Report Reveals New Challenges and Opportunities for Pharmaceutical Brands 3
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: