Navigation Links
Notre Dame researchers offer new insights on cancer cell signaling
Date:7/15/2013

noma. The study showed that a small molecule that prevents ARF6 activation could stop tumor invasion and the spread of the cancer.

"The relevance of Wnt signaling in human cancers in manifest by the frequency with which this pathway is aberrantly activated across a wide range of malignancies," D'Souza-Schorey said. "Given the number of Wnts, Wnt signaling has been difficult to target therapeutically. It is important to note that while there are many mechanisms that drive aberrant Wnt/beta-catenin signaling in diverse cancers, these different mechanisms nearly always occur in a mutually exclusive manner. Thus, a better understanding of mechanisms involved in Wnt signaling transduction offers several target molecules for cancer drug development."

Notre Dame graduate students James Clancy, Oscar Pellon-Cardenas, Alanna Sedgwick and Henriette Uwimphuwe were co-authors on the two studies from D'Souza-Schorey's laboratory.


'/>"/>

Contact: Crislyn D'Souza-Schorey
cdsouzas@nd.edu
574-631-3735
University of Notre Dame
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Notre Dame and Harper researchers developing novel method to test for HPV and oral cancers
2. New Notre Dame paper offers insights into how cancer cells avoid cell death
3. Notre Dame researchers scoring a win-win with novel set of concussion diagnostic tools
4. Notre Dame researchers paper examines the biology of tumor-derived microvesicles
5. Nanoparticles engineered at Notre Dame promise to improve blood cancer treatment
6. Use redistricting maps to make organ allocation more equitable, Johns Hopkins researchers advocate
7. Sanford-Burnham researchers develop novel nanoparticle to deliver powerful RNA interference drugs
8. Researchers investigate mechanism of Alzheimers therapy
9. Researchers pinpoint sources of fibrosis-promoting cells that ravage organs
10. Researchers use immunocytochemistry to determine ALK status
11. Researchers find 2 new methods to determine ALK status
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2014)... (PRWEB) July 24, 2014 Ticket Down ... Roma Tickets in Denver at the Sports Authority Field on ... (or World Football Challenge) has brought some of the best club ... With the World Cup still being raved about weeks after its ... chance to see some of the biggest stars in the world ...
(Date:7/24/2014)... The report, “Content Delivery Networks (CDN) ... various sub-segments with an in-depth analysis and forecasting ... restraints for this market with insights on trends, ... tables and 36 figures spread through 157 pages ... Market” at http://www.marketsandmarkets.com/Market-Reports/content-delivery-networks-cdn-market-657.html . , Early ...
(Date:7/24/2014)... (PRWEB) July 24, 2014 The ... http://www.injurybeacon.com/granuflo-dialysis/lawsuit/ ) in the U.S. District Court, ... order for plaintiff medical information covered by the ... to the July 16th Order, U.S. District Judge ... for Fresenius Medical Care the right to receive ...
(Date:7/24/2014)... In a July 9th article in the Money ... Lotus Blossom Consulting LLC , was quoted in a Family ... Cut the High Cost of Infertility . Her advice began ... maximize your chance of success from the first attempt.” The ... “I am always happy to talk with the media ...
(Date:7/24/2014)... announced its 2014 Power of A Award winners, including ... (ASA). , The ASA Global Humanitarian Outreach (GHO) ... of the top honors from ASAE. GHO was honored ... education on the global anesthesia crisis and supporting low ... also honored with a Power of A Silver Award ...
Breaking Medicine News(10 mins):Health News:Manchester United vs. AS Roma Tickets Denver Sports Authority Field at Mile High: Ticket Down Cuts Ticket Prices for Guinness International Champions Cup Match 2Health News:Manchester United vs. AS Roma Tickets Denver Sports Authority Field at Mile High: Ticket Down Cuts Ticket Prices for Guinness International Champions Cup Match 3Health News:CDN Market by Delivery Technologies & Solutions Expected to Reach $12.16 Billion by 2019 - New Report by MarketsandMarkets 2Health News:CDN Market by Delivery Technologies & Solutions Expected to Reach $12.16 Billion by 2019 - New Report by MarketsandMarkets 3Health News:CDN Market by Delivery Technologies & Solutions Expected to Reach $12.16 Billion by 2019 - New Report by MarketsandMarkets 4Health News:GranuFlo Lawsuits Move Forward in Federal Court, With Issuance of Protective Order for HIPAA Information, Bernstein Liebhard LLP Reports 2Health News:GranuFlo Lawsuits Move Forward in Federal Court, With Issuance of Protective Order for HIPAA Information, Bernstein Liebhard LLP Reports 3Health News:GranuFlo Lawsuits Move Forward in Federal Court, With Issuance of Protective Order for HIPAA Information, Bernstein Liebhard LLP Reports 4Health News:Mindy Berkson, Infertility Expert and Founder, Lotus Blossom Consulting LLC: Leading the Pathway to Parenthood 2Health News:Mindy Berkson, Infertility Expert and Founder, Lotus Blossom Consulting LLC: Leading the Pathway to Parenthood 3
... Mich. Women are under-represented in clinical cancer research ... by researchers at the University of Michigan Comprehensive Cancer ... types of cancer among women, studies included a smaller ... looked specifically at studies of cancer types that were ...
... New York Blood Center (NYBC) and its divisions in Manhattan, Long ... big challenges this season to maintain an adequate and safe blood ... One: Concerns About H1N1 (Swine Flu) ... were temporarily closed. The canceled drives have meant the loss ...
... do as well as surgery, especially in less severe cases ... the first line of treatment for diabetics who are also ... further steps are deemed necessary should invasive interventions such as ... The issue is crucial to millions of Americans, since diabetes ...
... Harkin to Host Event With ... , WASHINGTON, June 7 Barbara Manard, ... Homes and Services for the Aging (AAHSA), will join an esteemed ... briefing on current HELP efforts to include long-term services and support ...
... HOUSTON, June 6 The City of Houston and its ... Group,s 3rd Annual Houston Juneteenth Multicultural Health Festival (HJMHF) on ... Festival moves indoors to the George R. Brown Convention Center, ... than 180,000 square feet of air-conditioned exhibit space, this year,s ...
... tips to minimize golf-related injuries , SATURDAY, June 6 ... the body than many other sports, but don,t be fooled. ... of the bones, muscles or joints, warns the American Academy ... professionals treated more than 103,000 golf-related injuries in 2007. ...
Cached Medicine News:Health News:Women under-represented in cancer research, U-M study finds 2Health News:Our Communities' Blood Supply Faces Summer Challenges 2Health News:Our Communities' Blood Supply Faces Summer Challenges 3Health News:Drugs Best First Defense Against Heart Disease for Diabetics 2Health News:Drugs Best First Defense Against Heart Disease for Diabetics 3Health News:2009 Houston Juneteenth Multicultural Health Festival Becomes Largest Health Event in Texas: Festival Moves Indoors to the Cool George R. Brown 2Health News:Good Golf Form Can Improve Game and Prevent Pain 2
(Date:7/24/2014)... July 24, 2014 Many new dentists who are ... to ensure that their practice will be a success. DentalDisposables.net ... supplies they use the most can make all the difference. ... have recently discovered that purchasing discount dental supplies ... According to successful dentists across the United ...
(Date:7/24/2014)... July 24, 2014 Talyst, a market leader ... National Association of State Veterans Homes (NASVH) Summer Conference ... goal of the NASVH is to ensure that each ... long term health care and respect which they have ... With the InSite® Remote Dispensing System, Talyst can help ...
(Date:7/24/2014)... BURLINGTON, Mass. , July 24, 2014 ... asthma, pulmonologists in the EU5 countries ( France ... Italy , Spain and ... generally positive view of the first once-daily long-acting beta2 ... pulmonologists expect robust uptake of Relvar as a first-line ...
Breaking Medicine Technology:Dental Supplies Online is Key to Dental Success...Really! 2Talyst Exhibits at the National Association of State Veterans Homes Summer Conference 2Surveyed EU5 Pulmonologists Expect that Relvar, the First Once-Daily LABA/ICS FDC, Will Experience Healthy Uptake in Asthma 2Surveyed EU5 Pulmonologists Expect that Relvar, the First Once-Daily LABA/ICS FDC, Will Experience Healthy Uptake in Asthma 3
... Oct. 11 More than 170 industry experts and ... four executive workshops at AdvaMed 2010: The MedTech ... its fourth year, this annual medical technology industry developed ... U.S. and around the world.   "This ...
... Holdings Corp. (Nasdaq: TLCR ) will issue its ... October 28, 2010. Due to the pending merger with Grifols, ... discuss its third quarter results. About Talecris ... Talecris Biotherapeutics is a global biotherapeutic and biotechnology company ...
Cached Medicine Technology:Medical Technology, Funding & Government Experts Address Business, Investment, Reimbursement, Compliance, Innovation, Regulatory and Legal Issues at AdvaMed 2010 2Medical Technology, Funding & Government Experts Address Business, Investment, Reimbursement, Compliance, Innovation, Regulatory and Legal Issues at AdvaMed 2010 3
... mini-cells has always distinguished itself by ... tradition continues with the patented XCell ... gel tension wedge in place of ... models makes the XCell SureLock and ...
... Multidizer is designed with a variety of ... - all in one unit. Shake, rock, ... operating compartments allow for hybridization and blotting ... , The upper chamber uses a ...
... unit ideal for use in laboratories with low ... set at 12 rpm , Temperature control ... capacity of four 35 x 150mm bottles, eight ... , Consistent, repeatable results achieved with microprocessor ...
Maxi XL Hybridization Oven for Extra Large bottles. 6 bottle (70 mm) rotisserie + shaker tray available for simultaneous use. Includes linear and orbital shaker trays, 4 extra large bottles, pack o...
Medicine Products: