Navigation Links
Not just clean but spotless -- Researchers show how cells tidy up
Date:1/17/2014

Autophagy or how cells tidy up

"Bang and the dirt is gone!" There are many commercials for products that claim to make the unpopular process of cleaning up easier. But it's not only our surroundings that need to be kept clean. Even our cells need to tidy up. The responsible cellular process is called autophagy, in which the coordinated action of a set of proteins removes damaged cell material or pathogens, such as bacteria, from a cell. At the same time autophagy also helps cells to survive in times of starvation by recycling the cells' own components to produce energy, similar to recycling stations in a city.

The central player in autophagy: Atg1

For some time researcher had known the key coordinator of autophagy the protein Atg1. However, how Atg1 exactly does its job remained unclear, despite the efforts of many groups worldwide. Now, the team of Claudine Kraft at the Max F. Perutz Laboratories (MFPL) of the University of Vienna showed that Atg1 modifies a set of proteins with a specific recognition sequence. In collaboration with their colleagues Gustav Ammerer at MFPL and Ben Turk at the University of Yale, they not only deciphered the recognition sequence but also determined the cellular proteins that actually contain this sequence. One, Atg9, caught the interest of the researchers in particular, as it is not only a known component of the cellular "waste bag", but also contains a stunning six of those specific recognition sequences. Daniel Papinski, first author of the study, explains: "Every cell contains specialized recycling stations. In order to dispose its waste, a cell needs to wrap it up, similar to putting garbage in a bag. This cellular trash bag can then be brought to the cellular recycling station where the waste is broken down into the re-usable parts." Atg9 is essential for this process.

How does Atg1 coordinate the packaging of cellular waste?

To test how Atg1 precisely regulates the pa
'/>"/>

Contact: Lilly Sommer
lilly.sommer@mfpl.ac.at
43-142-772-4014
University of Vienna
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. New Product Bridges the Link between Colon Cleanse and Weight Loss
2. Strouse Cleanroom Now ISO 7 Certified
3. School of Juicing Review
4. How to Cleanse the Body Naturally With Foods – HealthReviewCenter
5. Mold Shuts Down 8 Loughman Oaks Elementary School Classrooms, My Cleaning Products Shares Mold Removal Tip How Others Could Prevent Same Problem
6. RMB Certifies ISO Class 7 Cleanroom for Plastic Fabrication
7. Total Wellness Cleanse Review
8. How This Program Helps People Detox Their Body Naturally – HealthReviewCenter
9. Bowtrol Colon Cleansing Treatment Now Offers Extra Discount on All Orders as New Year Special
10. Weight Loss Secrets of the Master Cleanse Detox Exposed By Detox Dieter
11. Total Body Cleanse and Detox Tips to Improve Health and Wellness Released by Detox Dieter
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Not just clean but spotless -- Researchers show how cells tidy up
(Date:9/17/2014)... New York, New York (PRWEB) September 17, 2014 ... ) filings involving the Conserve line of metal-on-metal ... litigation now underway in U.S. District Court, Northern ... to an updated Case List issued by the ... 15, 2014, at least 397 product liability claims ...
(Date:9/17/2014)... September 17, 2014 Boston Children’s ... create a monthly concert series, introducing young Museum ... the Top, America’s premier national platform celebrating the ... Many of the young musicians featured will also ... “Boston Children’s Museum is fortunate to partner with ...
(Date:9/17/2014)... 2014 Smart Flour Foods™ has been ... Grocer, a leading trade magazine targeted toward food retailers. ... and flavor, among other attributes. Smart Flour Foods’ Uncured ... in the September print issue of Progressive Grocer as ... pizza won based on its superior performance in the ...
(Date:9/17/2014)... Palo Alto, CA (PRWEB) September 17, 2014 ... with Stanford University, revealed 12 companies raising rounds of ... attended by a few hundred investors and media, was ... square foot headquarters located next to the university. The ... staff and volunteers, adjacent to StartX-QB3 Labs, a 2,000 ...
(Date:9/17/2014)... GA (PRWEB) September 17, 2014 Leading ... to announce the launch of its new vegan and ... is extremely effective and provided the results skincare testers ... to create a gentle yet active mask that provided ... Lake Louise.” , This Sugar Cane Fruit Mask combines ...
Breaking Medicine News(10 mins):Health News:Wright Hip Lawsuit News: Nearly 400 Filings Reported in Federal Wright Conserve Hip Replacement Litigation, Bernstein Liebhard LLP Reports 2Health News:Wright Hip Lawsuit News: Nearly 400 Filings Reported in Federal Wright Conserve Hip Replacement Litigation, Bernstein Liebhard LLP Reports 3Health News:Boston Children's Museum Partners with From the Top to Offer Monthly Concert Series 2Health News:Boston Children's Museum Partners with From the Top to Offer Monthly Concert Series 3Health News:Smart Flour Foods Wins 2014 Progressive Grocer Editor’s Pick Award 2Health News:Stanford-affiliated StartX Showcases Startups, New HQ, and Growth of Stanford-StartX Fund 2Health News:Stanford-affiliated StartX Showcases Startups, New HQ, and Growth of Stanford-StartX Fund 3Health News:Stanford-affiliated StartX Showcases Startups, New HQ, and Growth of Stanford-StartX Fund 4Health News:Stanford-affiliated StartX Showcases Startups, New HQ, and Growth of Stanford-StartX Fund 5Health News:Stanford-affiliated StartX Showcases Startups, New HQ, and Growth of Stanford-StartX Fund 6Health News:EcoBeauty Brand Lotus Moon Unveils New Gluten-Free Sugar Cane Fruit Mask 2
... doing away with the user charges imposed on patients at ... senior CPI(M) MP said today. ,This was conveyed to ... Basudeb Acharia when they called on Prime Minister Manmohan Singh ... Nirmala Deshpande and Hannan Mollah, met the Prime Minister weeks ...
... next week to repair a tennis elbow injury that has ... African vice-captain was forced out of last year's tour of ... the tour of Sri Lanka in August., ,'However, he ... in India in September and the 2007 World Cup in ...
... Intelligence arrested three persons, including the Managing Director ... alleged illegal export of Ephedrine tablets, a controlled ... Substances (NDPS) Act, 1985. ,According to ... persons have been remanded to judicial custody by ...
... by the Johns Hopkins researchers it is found that ... brain which controls// the muscle movements is responsible for ... research is Professor Reza Shadmehr and he and his ... PLoS Biology. This study would help to change the ...
... Royal Brisbane and Women's Hospital (RBWH), Sydney struggles with ... in three wards were found with a bacterium ... skin. ,To prevent the spread, 12 patients ... cent burns) were shifted to Sydney hospital and some ...
... the city, joined by members of Medical Representatives Association ... protest the Centre's reservation// proposals, affecting heatlh services in ... a number of women and ayurvedic doctors, also took ... to Prime Minister Manmohan Singh to the Deputy Commissioner, ...
Cached Medicine News:
(Date:9/17/2014)... , Sept. 17, 2014   GS1 US ... to implement GS1 Standards to support the 2013 ... patient safety and security in the pharmaceutical supply ... Standards to U.S. Pharmaceutical Supply Chain Business Processes ... , was developed in collaboration with GS1 ...
(Date:9/17/2014)... Calif. , Sept. 17, 2014 ... announced that it has earned a $4 million ... AKAO ) associated with the initiation of a ... serious multi-drug resistant (MDR), gram-negative bacterial infections.  The ... study to evaluate the efficacy and safety of ...
(Date:9/17/2014)... Sept. 17, 2014 Sutro Biopharma, a biopharmaceutical ... the biopharmaceutical division of Merck KGaA, Darmstadt, ... the United States and ... license agreement to develop antibody drug conjugates (ADCs). ADCs ... drug. The antibody is thought to specifically target and ...
Breaking Medicine Technology:New Healthcare Industry Guideline Delineates How to Implement GS1 Standards to Support Requirements of the 2013 Drug Supply Chain Security Act 2New Healthcare Industry Guideline Delineates How to Implement GS1 Standards to Support Requirements of the 2013 Drug Supply Chain Security Act 3New Healthcare Industry Guideline Delineates How to Implement GS1 Standards to Support Requirements of the 2013 Drug Supply Chain Security Act 4Isis Pharmaceuticals Earns $4 Million from Achaogen for the Initiation of a Phase 3 Study of Plazomicin 2Isis Pharmaceuticals Earns $4 Million from Achaogen for the Initiation of a Phase 3 Study of Plazomicin 3Sutro Biopharma and Merck KGaA of Darmstadt, Germany, to Partner on Development of Antibody Drug Conjugates 2Sutro Biopharma and Merck KGaA of Darmstadt, Germany, to Partner on Development of Antibody Drug Conjugates 3Sutro Biopharma and Merck KGaA of Darmstadt, Germany, to Partner on Development of Antibody Drug Conjugates 4
... Nov. 2, 2010 GeNO LLC ( www.genollc.com ... announced today that it has submitted an Investigational ... and Drug Administration (FDA) for the GeNO NITROsyl ... pulmonary hypertension in patients with pulmonary arterial hypertension ...
... , a drug research and development company focused on the ... awarded a grant by the United States government under the ... of its lead product CM-AT for autism.  CM-AT is presently ... US. The QTDP grant program provides support for ...
Cached Medicine Technology:GeNO LLC Submits Investigational New Drug Application for Its NITROsyl™ Inhaled Nitric Oxide System to Treat Chronic Pulmonary Hypertension 2GeNO LLC Submits Investigational New Drug Application for Its NITROsyl™ Inhaled Nitric Oxide System to Treat Chronic Pulmonary Hypertension 3Curemark Awarded Qualifying Therapeutic Discovery Project (QTDP) Grant 2
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: