Navigation Links
Normal weight individuals with belly fat at highest CVD risk
Date:8/27/2012

Munich, Germany Normal weight individuals who carry weight concentrated in their belly have a higher death risk than obese individuals, according to research presented at ESC Congress 2012. The results were presented by Dr Karine Sahakyan from the Mayo Clinic.

"We knew from previous research that central obesity is bad, but what is new in this research is that the distribution of the fat is very important even in people with a normal weight," said Dr Francisco Lopez-Jimenez, senior author on the study and a cardiologist at the Mayo Clinic in Rochester, Minnesota. "This group has the highest death rate, even higher than those who are considered obese based on BMI. From a public health perspective, this is a significant finding."

The study included 12,785 subjects aged 18 years and older from the Third National Health and Nutrition Examination Survey (NHANES III) and provided a representative sample of the United States population. The surveys recorded body measurements such as height, weight, waist circumference and hip circumference, as well as socioeconomic status, comorbidities, physiological and laboratory measurements. Baseline data were matched to the National Death Index to assess deaths at follow up.

Subjects were divided into three categories of BMI (normal: 18.5-24.9kg/m2; overweight: 25.0-29.9kg/m2; and obese: >30kg/m2) and two categories of waist-to-hip ratio (normal: <0.85 in women and <0.90 in men; high: ≥0.85 in women and ≥0.90 in men). Analyses were adjusted for age, sex, race, smoking, hypertension, diabetes, dyslipidemia and baseline BMI. Subjects with chronic obstructive pulmonary disease and cancer were excluded.

The mean age of subjects was 44 years old and 47.4% were men. The median follow up period was 14.3 years. There were 2,562 deaths, of which 1,138 were cardiovascular related.

The subjects with normal BMI but central obesity as defined by a high waist-to-hip ratio had the highest cardiovascular death risk and the highest death risk from all causes among the six subgroups. The risk of cardiovascular death was 2.75 times higher and the risk of death from all causes was 2.08 times higher in normal weight obese people as compared with subjects with normal BMI and normal waist-to-hip ratio.

"To our knowledge it is the first study that evaluated nationwide estimates of death in central obesity even in the absence of obesity as measured by BMI," said Dr Sahakyan, who is a cardiology research fellow at the Mayo Clinic in Rochester. "The high risk of death may be related to a higher visceral fat accumulation in this group, which is associated with insulin resistance and other risk factors, the limited amount of fat located on the hips and legs, which is fat with presumed protective effects and to the relatively limited amount of muscle mass."

"Many people today know their BMI," added Dr Lopez-Jimenez. "Our research shows that if a person has a normal BMI, this by itself should not reassure them that their risk for heart disease is low. Where their fat is distributed on their body can mean a lot, and that can be determined easily by getting a waist-to-hip measurement, even if their body weight is within normal limits."

Dr Sahakyan concluded: "Health professionals need to educate patients about the importance of having a healthy weight and a normal weight-to-hip ratio. Promotion of healthy lifestyle including healthy eating and exercise is perhaps the best strategy."


'/>"/>

Contact: ESC Press Office
press@escardio.org
33-049-294-8627
European Society of Cardiology
Source:Eurekalert

Related medicine news :

1. Epilepsy Leads to More Brain Abnormalities Over Time
2. Normal triglyceride levels in people of African descent may hinder diagnosis of metabolic syndrome
3. Normalizing tumor blood vessels improves delivery of only the smallest nanomedicines
4. Study Pinpoints New Abnormality in Athletes Heart
5. Slow-growing babies more likely in normal-weight women; Less common in obese pregnancies
6. Insecticide Linked to Brain Abnormalities in Kids
7. Genetic abnormalities in benign or malignant tissues predict relapse of prostate cancer
8. Treatment of childhood OSA reverses brain abnormalities
9. Abnormal gene product associated with prostate cancer generated by unusual mechanism
10. Declining testosterone levels in men not part of normal aging, study finds
11. Genome-wide analysis shows previously undetected abnormalities in parents of affected children
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/19/2017)... ... August 19, 2017 , ... Parker at Stonegate, an assisted ... passionate employees, caregivers, volunteers, thought leaders, researchers, educators and partners leading the way ... time to refresh the carpeting with the goal of maintaining the same precise ...
(Date:8/18/2017)... ... ... More than 20,000 pairs of shoes made their way across the Atlantic this ... conjoined the passions of an NBA star, a Liberty University student, and an LU ... save lives from the rampant infections transmitted through the soil. , AMERICAN SOLES , ...
(Date:8/18/2017)... ... August 18, 2017 , ... ... of “Vision & Hearing,” advocating for active, healthy lifestyles and highlighting the importance ... for individuals with hearing impairments and shares the latest innovations in hearing aid ...
(Date:8/18/2017)... , ... August 18, 2017 , ... ... services and financial consultations to communities throughout the greater DC region, is inaugurating ... the goal of rescuing local animals and training them to be companions for ...
(Date:8/18/2017)... John, IN (PRWEB) , ... August 18, 2017 , ... ... to communities in northwest Indiana, is campaigning in support of Campagna Academy in a ... referred to as the “Hoosier Boys’ Town of Indiana,” Campagna Academy is a nonprofit ...
Breaking Medicine News(10 mins):
(Date:8/8/2017)... 8, 2017  BioLineRx Ltd. (NASDAQ/TASE: BLRX), a clinical-stage ... its financial results for the second quarter ended June ... second quarter 2017 and to date: ... programs for the Company,s lead project, BL-8040: ... with BL-8040 as novel stem cell mobilization treatment for ...
(Date:8/7/2017)... (NYSE: DPLO), the nation,s largest independent specialty pharmacy, announced financial ... unless otherwise noted, are to the quarter ended June 30, ... 2017 Highlights include: Revenue of $1,126 ... Total prescriptions dispensed of 220,000, compared to 241,000 ... Gross profit per prescription dispensed of $371, ...
(Date:8/2/2017)... , Aug. 2, 2017 ... Who,s Who as a Pinnacle Lifetime Professional in ... Key Account Manager at Turing Pharmaceuticals, AG. Her ... troubleshooting and relationship building.                ... more than 25 years of experience as a ...
Breaking Medicine Technology: