Navigation Links
Normal Pregnancies May Be Misdiagnosed as Ectopic

FRIDAY, Jan. 13 (HealthDay News) -- Women with normal pregnancies that were misdiagnosed as ectopic who were treated with methotrexate in the first trimester either miscarried or gave birth to a severely deformed baby, the results of a small study suggest.

An ectopic pregnancy is one where the egg begins to develop outside the womb, which means that the fetus cannot grow normally and will not survive. The drug methotrexate (Rheumatrex, Trexall), which is used to treat rheumatoid arthritis and certain types of cancer, is also known to be dangerous to developing fetuses and can end an ectopic pregnancy.

Researchers affiliated with the Organization of Teratology Information Specialists (OTIS) cautioned that their findings, published in the December issue of the American Journal of Obstetrics & Gynecology, may be a red flag for a larger problem. They said more effective tools are needed to properly diagnose ectopic pregnancies.

"This report describes a subset of cases that occur in the general population and it suggests that this misdiagnosis is not limited to one center or one part of the United States or Canada," Sharon Lavigne, study co-author and coordinator of OTIS' Connecticut affiliate, said in a news release from the organization. "There are likely many more of these scenarios out there that our services never hear about," she added.

For the study, the researchers examined eight North American women with normal pregnancies that were misdiagnosed as ectopic. The women were given high doses of methotrexate, which resulted in miscarriage, termination of the pregnancy or the birth of severely malformed babies. The investigators concluded that more accurate and effective tools are needed to diagnose and treat ectopic pregnancy.

"This is a challenging diagnosis, and efforts to accurately locate the pregnancy in suspected early ectopic pregnancies would benefit from improved diagnostic tools," another study co-author, Myla Moretti, assistant director of Motherisk, OTIS' Canadian affiliate, explained in the news release. "Establishing a non-punitive reporting mechanism to explore the magnitude of this problem will be helpful in increasing awareness and possibly preventing these events in the future."

More information

The U.S. National Institutes of Health has more about ectopic pregnancy.

-- Mary Elizabeth Dallas

SOURCE: Organization of Teratology Information Specialists, news release, Jan. 6, 2012

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Statins may increase risk of interstitial lung abnormalities in smokers
2. Study reveals how normal cells fuel tumor growth
3. First analysis of tumor-suppressor interactions with whole genome in normal human cells
4. Depression and anxiety not linked to delayed resolution of abnormal mammograms, Pap tests
5. Study evaluates normal range systolic bp levels after ischemic stroke and risk of recurrent stroke
6. Antidepressant linked to developmental brain abnormalities in rodents
7. Could Airway Abnormality Point to Autism?
8. Abnormal Protein May Explain Loss of Smell With Alzheimers
9. How normal cells become brain cancers
10. Scientists identify a key molecule that blocks abnormal blood vessel growth in tumors
11. Certain Risk Factors Could Spur Heart Failure in Normal-Weight People
Post Your Comments:
Related Image:
Normal Pregnancies May Be Misdiagnosed as Ectopic
(Date:11/25/2015)... ... November 25, 2015 , ... Finnleo, a leader in the traditional ... models of traditional and far-infrared saunas. , For traditional saunas, Finnleo is ... traditional Finnish sauna wood, and Finnleo uses only European Grade A Nordic White Spruce ...
(Date:11/25/2015)... ... 26, 2015 , ... Ministers, senior government and UN agencies, ... Centres of Excellence, and public R&D institutions, civil societies and other partners gathered ... 5th African Network for Drugs and Diagnostics Innovation, ANDI, Stakeholders Meeting. The three- ...
(Date:11/25/2015)... ... November 25, 2015 , ... Lakeview Health, a Jacksonville-based drug ... their sobriety and show through pictures what a positive difference it makes. The ... with the hashtag #FacesOfGratitude on their Facebook, Twitter, and Instagram accounts. Short ...
(Date:11/25/2015)... ... November 25, 2015 , ... The McHenry County law firm of ... decision obtained by Attorneys Francisco J. Botto and Alex C. Wimmer. Attorneys Botto and ... Comm’n, 2015 IL App (2d) 130884WC. , According to court documents, Adcock testified that ...
(Date:11/25/2015)... (PRWEB) , ... November 25, 2015 , ... Beddit® has ... Beddit Classic sleep tracking systems. The new app features a more intuitive SleepScore™ that ... understand how well you slept. The SleepScore is created by a proprietary algorithm. Beddit ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... 25, 2015 Allergan plc (NYSE: ... Rugen Therapeutics, a start-up  biotechnology company focused on ... disorders and funded by the F-Prime Biomedical Research ... into an exclusive collaboration to support the discovery ... Disorders (ASD) and Obsessive Compulsive disorders (OCD). ...
(Date:11/25/2015)... 2015 USP 800 applies to all ... pharmacists, pharmacy technicians, nurses, physicians, physician assistants, home ... also covers all entities which store, prepare, transport, ... healthcare institutions, patient treatment clinics, physicians, practice facilities, ... --> What is the purpose of ...
(Date:11/25/2015)... 2015 Asia -based ... BioLight and the New Investors will make a direct ... a private placement. The financing will help IOPtima to ... used in the treatment of glaucoma, as well as ... IOPtimate™ system with the U.S. Food and Drug Administration, ...
Breaking Medicine Technology: