Navigation Links
Noninvasive diagnostics may offer alternative to liver biopsy for assessing liver fibrosis
Date:6/2/2011

Patients who are evaluated for liver diseases such as hepatitis C (HCV) are typically recommended for liver biopsy to determine the extent of disease progression. For patients who question whether less invasive testing is available, clinicians now have alternatives options to consider. Elastography and serum markers are two such diagnostic options reviewed in an editorial published in the June issue of Hepatology, a journal of the American Association for the Study of Liver Diseases.

Epidemiological studies report that approximately 150,000 individuals in the U.S. are diagnosed with chronic liver disease each year, and nearly 20% of these cases have cirrhosis at initial presentation. Complications from cirrhosis are determined by the extent and progression of fibrosis or scaring of the liver. Liver fibrosis, however, is not a linear process, but one that fluctuates with the influences of age, sex, race, alcohol exposure and obesity.

Liver biopsy remains the gold standard for determining activity and stage of fibrosis. However, this procedure has inherent limitations that include risk of pain or bleeding, inaccurate staging from sampling error, and variability of biopsy interpretation. With the increase in availability of sophisticated laboratory blood testing, the use of diagnostic liver biopsy is on the decline. "The drawbacks to liver biopsy have prompted researchers to investigate alternative, noninvasive markers for determining the severity of liver disease," said Dr. Jayant Talwalkar of the Mayo Clinic in Rochester, MN and editorial co-author.

Noninvasive screening with serum markers, or indicators in the blood, can identify patients at risk for liver fibrosis. Fibrotest, an indirect serum marker panel, is the most widely used and validated serum marker panel used worldwide. A number of studies have confirmed this panel to be reliable in detecting stage 4 fibrosis (cirrhosis) in patients with chronic HCV. Additional stud
'/>"/>

Contact: Dawn Peters
healthnews@wiley.com
781-388-8408
Wiley-Blackwell
Source:Eurekalert

0

GOOD

Page: 1 2

Related medicine news :

1. Mayo Clinic reports new findings on noninvasive test for pancreatic cancer
2. GEN reports on novel noninvasive tests for early cancer detection
3. Noninvasive extenders are better than surgery for men who want a longer penis
4. Noninvasive Test May Identify Down Syndrome Early On
5. Noninvasive test for trisomy 21 closer at hand
6. Noninvasive Glaucoma Test Might Speed Up Detection
7. Noninvasive brain stimulation helps improve motor function in stroke patients
8. Noninvasive Test for Colon Cancer Shows Promise in Early Trial
9. Prediction tool helps estimate local recurrence in patients with noninvasive breast cancer
10. Noninvasive combination technique may reduce number of breast biopsies
11. New research shows innovative respiratory stress test can quickly detect significant coronary artery disease in a noninvasive setting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/25/2013)... Sun City Center, FL (PRWEB) May 25, 2013 ... years, is one of many of the NALA’s businesses throughout ... Owner, Craig Amshel chose to participate in the nationwide event ... served as a Lieutenant Colonel in the Army. He said, ... work in the community I serve, but I live here ...
(Date:5/25/2013)... Pradaxa lawsuits filed on ... internal bleeding while using the blood thinner continue to mount ... District of Illinois, Bernstein Liebhard LLP reports. According to ... claims had been filed in the litigation as ... reported by the Court on May 15th. ( In Re: ...
(Date:5/25/2013)... May 25, 2013 By working diligently ... declared the integration of the 2012 Lamborghini Aventador into ... the latest entrant in the list of vehicles lined ... vehicle is all set to thrill automobile lovers in ... power and spectacular looks, the 2012 Lamborghini Aventador comes ...
(Date:5/25/2013)... (PRWEB) May 25, 2013 According ... Emergency Management Market, 2013–2018", published by MarketsandMarkets is ... a CARC of 5.54% which analyzes and studies ... North America, Europe, Asia, and Rest of the ... Market Data Tables , 87 Figures ...
(Date:5/25/2013)... (PRWEB) May 25, 2013 Dr. Farooq ... surgery clinic in Dubai, has announced his practice’s adoption ... is the only FDA-cleared femtosecond laser proven with more ... safety and precision of LASIK. , “We are happy ... Advanced Femtosecond Laser at our Dubai LASIK practice,” Ashraf ...
Breaking Medicine News(10 mins):Health News:Dr. Craig Amshel of Absolute Surgical Specialists Offering Bowel Prep During the Shop Local for a Cause Event 2Health News:Pradaxa Lawsuits Mount, as Filings in Federal Pradaxa Side Effect Litigation Exceed 800, Bernstein Liebhard LLP Reports 2Health News:Pradaxa Lawsuits Mount, as Filings in Federal Pradaxa Side Effect Litigation Exceed 800, Bernstein Liebhard LLP Reports 3Health News:Rim Fitments Provider SizeItUp Launches The Database Integration For The 2012 Lamborghini Aventador 2Health News:Homeland Security Market to Reach $544.02 Billion by 2018 at a CARC of 5.54% - New Report by MarketsandMarkets 2Health News:Homeland Security Market to Reach $544.02 Billion by 2018 at a CARC of 5.54% - New Report by MarketsandMarkets 3Health News:Homeland Security Market to Reach $544.02 Billion by 2018 at a CARC of 5.54% - New Report by MarketsandMarkets 4Health News:Atlanta Vision Clinic Acquires the Latest in Blade-Free Lasik Technology Bringing Dubai Patients the Intralase Method 2
... researchers found that radiant-light therapy may be an effective ... an associate professor of psychiatry at the Yale School ... of an easy-to-use, potentially non-toxic antidepressant light therapy in ... conducted a pilot experiment to see whether exposure to ...
... a new study, fibrin, a protein that helps form blood ... nerve damage. The discovery could lead to new strategies for ... although the research is still on the basic science ... thin, protective coating that insulates nerve fibers in the brain ...
... According to a new research, high levels of a ... the risk for potentially lethal blood clots. Researchers at ... tendency to develop dangerous blood clots, but the relationship ... ,To find the reason, scientists led by Dr. ...
... Clinic felt that, one should not assume sneezing and watery ... sneeze during the spring months, you may well assume it's ... negative, the only solution or diagnosis might be pollen allergy.// ... a condition as non-allergic rhinitis. Here the inner lining of ...
... computer screening program can accurately diagnose a heart attack even ... a study of more than 1,000 adults who went to ... more than 80% of people who were having a heart ... be able to rely on the computer program to diagnose ...
... way to predict risk of surgery. Lens as thick ... complications are developing after coronary bypass surgery. The main ... re-block, risking heart attack and requiring further treatment.// If ... detected at an early stage, it's possible that such ...
Cached Medicine News:Health News:Clotting Protein plays a role in nerve repair 2Health News:Computer Program can assist to detect Heart Attack 2
(Date:5/24/2013)...  Heska Corporation (NASDAQ: HSKA, "Heska" or the "Company"), a ... that Dr. Robert Grieve , the Company,s ... , executive vice president and chief financial officer, will ... being held May 30, 2013 in New York ... The Company,s presentation is scheduled to begin at 1:30 ...
(Date:5/24/2013)... 24, 2013  Sinovac Biotech Ltd. (NASDAQ: ... products in China , announced ... of Sinovac, obtained the Certificate of Good Manufacturing ... China State and Food Administration (CFDA) for its ... and its Changping filing and packaging facility. The ...
(Date:5/23/2013)... Inc. (Vanda) (NASDAQ: VNDA ) today announced that ... of the Year by the Tech Council of ... 25 th Annual Tech Awards Celebration held in ... the leaders and innovators in the technology and life science ... regions. "We are deeply honored to receive ...
Breaking Medicine Technology:Heska Corporation To Present At The Second Annual Marcum LLP MicroCap Conference 2Sinovac Beijing Obtains China GMP Certificate Under the New GMP Guidelines 2Sinovac Beijing Obtains China GMP Certificate Under the New GMP Guidelines 3Vanda Pharmaceuticals Named the 2013 Life Science Firm of the Year by the Tech Council of Maryland 2
... -,Phytopharm plc (LSE: PYM) ("Phytopharm" or the ... reverses the,changes in the area of the ... be presented by Dr Jonathan Brotchie, an,internationally ... International Congress of Parkinson's Disease and Movement,Disorders' ...
... the Companies' Novel Heat Shock Protein 90 ... Biological,Activity , CAMBRIDGE, Mass. and GAITHERSBURG, Md., ... Inc. (Nasdaq:INFI) and,MedImmune, Inc. (Nasdaq:MEDI) today announced ... trial of the companies' heat shock,protein 90 ...
Cached Medicine Technology:Cogane Data Presented at ‘11th International Congress of,Parkinson’s Disease and Disorders’ 2Cogane Data Presented at ‘11th International Congress of,Parkinson’s Disease and Disorders’ 3Cogane Data Presented at ‘11th International Congress of,Parkinson’s Disease and Disorders’ 4Cogane Data Presented at ‘11th International Congress of,Parkinson’s Disease and Disorders’ 5Infinity and MedImmune Present Updated Phase I Results of IPI-504,in GIST at ASCO Annual Meeting 2Infinity and MedImmune Present Updated Phase I Results of IPI-504,in GIST at ASCO Annual Meeting 3Infinity and MedImmune Present Updated Phase I Results of IPI-504,in GIST at ASCO Annual Meeting 4Infinity and MedImmune Present Updated Phase I Results of IPI-504,in GIST at ASCO Annual Meeting 5Infinity and MedImmune Present Updated Phase I Results of IPI-504,in GIST at ASCO Annual Meeting 6Infinity and MedImmune Present Updated Phase I Results of IPI-504,in GIST at ASCO Annual Meeting 7
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: