Navigation Links
Noninvasive diagnostics may offer alternative to liver biopsy for assessing liver fibrosis
Date:6/2/2011

Patients who are evaluated for liver diseases such as hepatitis C (HCV) are typically recommended for liver biopsy to determine the extent of disease progression. For patients who question whether less invasive testing is available, clinicians now have alternatives options to consider. Elastography and serum markers are two such diagnostic options reviewed in an editorial published in the June issue of Hepatology, a journal of the American Association for the Study of Liver Diseases.

Epidemiological studies report that approximately 150,000 individuals in the U.S. are diagnosed with chronic liver disease each year, and nearly 20% of these cases have cirrhosis at initial presentation. Complications from cirrhosis are determined by the extent and progression of fibrosis or scaring of the liver. Liver fibrosis, however, is not a linear process, but one that fluctuates with the influences of age, sex, race, alcohol exposure and obesity.

Liver biopsy remains the gold standard for determining activity and stage of fibrosis. However, this procedure has inherent limitations that include risk of pain or bleeding, inaccurate staging from sampling error, and variability of biopsy interpretation. With the increase in availability of sophisticated laboratory blood testing, the use of diagnostic liver biopsy is on the decline. "The drawbacks to liver biopsy have prompted researchers to investigate alternative, noninvasive markers for determining the severity of liver disease," said Dr. Jayant Talwalkar of the Mayo Clinic in Rochester, MN and editorial co-author.

Noninvasive screening with serum markers, or indicators in the blood, can identify patients at risk for liver fibrosis. Fibrotest, an indirect serum marker panel, is the most widely used and validated serum marker panel used worldwide. A number of studies have confirmed this panel to be reliable in detecting stage 4 fibrosis (cirrhosis) in patients with chronic HCV. Additional stud
'/>"/>

Contact: Dawn Peters
healthnews@wiley.com
781-388-8408
Wiley-Blackwell
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Mayo Clinic reports new findings on noninvasive test for pancreatic cancer
2. GEN reports on novel noninvasive tests for early cancer detection
3. Noninvasive extenders are better than surgery for men who want a longer penis
4. Noninvasive Test May Identify Down Syndrome Early On
5. Noninvasive test for trisomy 21 closer at hand
6. Noninvasive Glaucoma Test Might Speed Up Detection
7. Noninvasive brain stimulation helps improve motor function in stroke patients
8. Noninvasive Test for Colon Cancer Shows Promise in Early Trial
9. Prediction tool helps estimate local recurrence in patients with noninvasive breast cancer
10. Noninvasive combination technique may reduce number of breast biopsies
11. New research shows innovative respiratory stress test can quickly detect significant coronary artery disease in a noninvasive setting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/20/2014)... York (PRWEB) December 20, 2014 ... to move forward in U.S. courts, Bernstein Liebhard ... which suggests that children treated with the medication ... linked to breast development and lactation. The study, ... 34 children and adolescents who began treatment with ...
(Date:12/20/2014)... Developers of FCPX 3rd ... plugin for Final Cut Pro X entitled TranSlice Volume ... allows users to create hand drawn text animations without ... CEO of Pixel Film Studios. “TranSlice Volume 5 was ... an easy to use interface.” , TranSlice Volume 5 ...
(Date:12/20/2014)... December 20, 2014 Today, Balfleet.com, one ... a Christmas Sale, offering 50%-70% off on its ... season. , The mother of the bride dresses from ... company is 24/7 accessible and takes pride in providing ... , “We are offering great discounts on our mother ...
(Date:12/19/2014)... (PRWEB) December 19, 2014 Sub Zero Ice ... sponsor a blood drive Sunday the 28th from 2pm-6pm at ... & Sawyer Road in Sarasota, FL. , Inquiries regarding time ... you for participating in the donating process, Sub Zero Ice ... flash frozen, custom ice cream. , About Sub Zero Ice ...
(Date:12/19/2014)... December 19, 2014 SuperCloset raises the ... Rooms. SuperCloset continues to offer indoor growers the most ... of the new SuperClone Rooms with the award winning ... turnkey indoor hydroponic grow room setup. , The SuperClone ... SuperCloset’s SuperPonic SuperCloner 50 . The ...
Breaking Medicine News(10 mins):Health News:Risperdal Lawsuit News: Bernstein Liebhard LLP Notes Publication of Study Suggesting Medication May Raise Prolactin Levels in Children 2Health News:Risperdal Lawsuit News: Bernstein Liebhard LLP Notes Publication of Study Suggesting Medication May Raise Prolactin Levels in Children 3Health News:Risperdal Lawsuit News: Bernstein Liebhard LLP Notes Publication of Study Suggesting Medication May Raise Prolactin Levels in Children 4Health News:Pixel Film Studios released a new transition entitled TranSlice Volume 5 exclusively for Final Cut Pro X 2Health News:Balfleet.com is Offering 50%-70% Off of its Mother of the Bride Dresses 2Health News:Shark Tank’s Sub Zero Ice Cream Sponsors Blood Drive 2Health News:SuperCloset Continues to Innovate with New Complete Indoor Grow Room Packages, The SuperClone Rooms are the Newest Addition to the Award Winning SuperRoom Lineup 2
... and Eons.com founder Jeff Taylor and,futurist Leanne Kaiser ... SAN DIEGO, Oct. 9 The following ... Washington, D.C.-based independent accreditor that,offers more than 20 ... Currently URAC accredits more than 400 health care,management ...
... a multicenter study led by Johns Hopkins Children,s Center ... hydrocortisone, a steroid believed to fight inflammation and prevent ... little or no benefit and that low cortisol levels ... the other hand, appeared to increase the risk of ...
... in early 2009 -, CORONA, Calif., Oct. ... a leading specialty pharmaceutical,company, announced today that the ... (silodosin), the company,s new alpha blocker for,the treatment ... BPH is the number one reason patients visit ...
... 8 Continuing its efforts to,educate, inform and ... a,not-for-profit patient-focused organization, is hosting its 25-minute live,call-in ... on,Monday, October 13, 2008 at 6:00 PM on ... in-depth discussion of women,s health,with Deborah Edberg, MD, ...
... Online Press Registration Closes Next Friday, WASHINGTON, ... meet in San Diego, Calif., Oct. 25-29, to ... American Public Health,Association,s (APHA) 136th Annual Meeting., ... presenting the latest public health science at nearly ...
... production in the newly diagnosed. , , WEDNESDAY, Oct. 8 ... that may change the way the immune system responds ... diabetes. , "By a very simple vaccination, without adverse ... insulin secretion, which may be extremely important for diabetic ...
Cached Medicine News:Health News:Health Care Management Thought Leaders Converge for Summit on Cost, Quality and Consumer Focus 2Health News:Steroid treatment offers no benefit in preemies, Hopkins Children's study suggests 2Health News:Steroid treatment offers no benefit in preemies, Hopkins Children's study suggests 3Health News:Watson Receives US FDA Approval for RAPAFLO(TM) (silodosin) for the Treatment of Benign Prostatic Hyperplasia (BPH) 2Health News:Watson Receives US FDA Approval for RAPAFLO(TM) (silodosin) for the Treatment of Benign Prostatic Hyperplasia (BPH) 3Health News:Watson Receives US FDA Approval for RAPAFLO(TM) (silodosin) for the Treatment of Benign Prostatic Hyperplasia (BPH) 4Health News:Women's Health - An Intimate Discussion 2Health News:Thousands of Public Health Experts to Address Leading Issues at APHA Annual Meeting, Oct. 25-29 2Health News:New Vaccine May Help Type 1 Diabetics in Future 2Health News:New Vaccine May Help Type 1 Diabetics in Future 3
(Date:12/19/2014)... 18, 2014 Capnia, Inc. (NASDAQ: ... medical diagnostics based on its proprietary Sensalyze™ Technology ... announced financial results for the third quarter and ... "Following the completion of our initial public offering ... the recently initiated CoSense® commercial launch," said Anish ...
(Date:12/19/2014)... LYON, France , Dec. 19, 2014 /PRNewswire/ ... and Adocia (Euronext Paris: FR0011184241 – ADOC) today announced ... insulin, known as BioChaperone Lispro, for treatment in people ... relies on Adocia,s proprietary BioChaperone® technology and is currently ... will develop BioChaperone Lispro with the goal of optimizing ...
(Date:12/17/2014)... Dec. 17, 2014  Strategic Health Services, Inc. (SHS), ... today announced a strategic agreement with QualCare, Inc., a leading ... Jersey regional marketplace.  This agreement will further ... and wellness solutions QualCare brings to its clients in ... region. QualCare plans cover more than ...
Breaking Medicine Technology:Capnia Reports Third Quarter 2014 Financial Results 2Capnia Reports Third Quarter 2014 Financial Results 3Capnia Reports Third Quarter 2014 Financial Results 4Capnia Reports Third Quarter 2014 Financial Results 5Capnia Reports Third Quarter 2014 Financial Results 6Capnia Reports Third Quarter 2014 Financial Results 7Capnia Reports Third Quarter 2014 Financial Results 8Lilly and Adocia Announce Alliance to Co-Develop Ultra-Rapid Insulin Based on BioChaperone Technology 2Lilly and Adocia Announce Alliance to Co-Develop Ultra-Rapid Insulin Based on BioChaperone Technology 3Strategic Health Services to collaborate with QualCare on Population Health and Wellness Technology for QualCare Members 2Strategic Health Services to collaborate with QualCare on Population Health and Wellness Technology for QualCare Members 3
... Today is an exciting day for men with advanced prostate ... affected. Today a new prostate cancer treatment option, Provenge, was approved by ... , , ... innovative treatment option made available for patients with asymptomatic or minimally symptomatic ...
... Dendreon Corporation (Nasdaq: DNDN ) ... Administration (FDA) has approved PROVENGE® (sipuleucel-T), an autologous ... minimally symptomatic metastatic, castrate-resistant (hormone-refractory) prostate cancer (CRPC). ... against prostatic acid phosphatase (PAP), an antigen expressed ...
Cached Medicine Technology:Advanced Prostate Cancer Patients Finally Have Another Option 2FDA Approves PROVENGE(R) for the Treatment of Men with Advanced Prostate Cancer 2FDA Approves PROVENGE(R) for the Treatment of Men with Advanced Prostate Cancer 3FDA Approves PROVENGE(R) for the Treatment of Men with Advanced Prostate Cancer 4FDA Approves PROVENGE(R) for the Treatment of Men with Advanced Prostate Cancer 5FDA Approves PROVENGE(R) for the Treatment of Men with Advanced Prostate Cancer 6FDA Approves PROVENGE(R) for the Treatment of Men with Advanced Prostate Cancer 7
... a mesh plug to treat large or ... hernias and femoralhernias. The self-expanding plug perfectly ... completely. Premilene Mesh Self-Forming Plug is a ... Mesh. The plug corresponds with all properties ...
... Lightweight and ergonomically designed with a 10-foot, ... Megadyne's E-Z PEN reusable electrosurgical pencils are ... the patented E-Z CLEAN non-stick tips allowing ... faster. The E-Z CLEAN PTFE coating ...
... Applied Fiberoptics Gemini surgical headlight is perfectly ... is durable and ultra-low-profile and illuminates brilliantly ... the annoying "rams effect." The fully adjustable ... designed to sit low on the brow, ...
... ... , ... MC-3 with Multiport - A three-lamp lightsource , it ... reserved for backup. Designed with managed care in mind, it includes universal turrets to accept most ...
Medicine Products: