Navigation Links
Noninvasive Test for Colon Cancer Shows Promise in Early Trial
Date:10/28/2010

cancer sponsored by the American Association for Cancer Research.

The new technology, called the Cologuard sDNA test, works by identifying specific altered DNA in cells shed by pre-cancerous or cancerous polyps into the patient's stool.

If a DNA abnormality is found, a colonoscopy would still be needed to confirm the results, just as happens now after a positive fecal occult blood test (FOBT) result.

To see whether the test was effective, Ahlquist's team tried it out on more than 1,100 frozen stool samples from patients with and without colorectal cancer.

The test was able to detect 85.3 percent of colorectal cancers and 63.8 percent of polyps bigger than 1 centimeter. Polyps this size are considered pre-cancers and most likely to progress to cancer, Ahlquist said.

The sensitivity of the test is much better than what has been seen in other stool screening tests, the ACS' Brooks added. "But, showing that in a small group of samples is very different from demonstrating that in a population where only a small number of individuals are going to have polyps of that size. Then we will know if this is a big step forward," he said.

According to Ahlquist, Cologuard is the first noninvasive test to detect pre-cancerous polyps, he added.

In addition, the test is the only one that is able to identify cancer in all locations throughout the colon, something which other tests either can't or don't do well, Ahlquist said.

One more advantage: patients do not need to do any special preparation before taking the test, something that other tests require, he added.

Ahlquist noted that the test still needs to be refined. "We learned there are still some bugs and we can make the test even better," he said.

Cologuard is not yet available for sale. Clinical trials comparing the test with colonoscopy are slated to start next year. Ahlquist hopes that the test will be approved and available within two years.

Ahlquist
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3 4

Related medicine news :

1. Prediction tool helps estimate local recurrence in patients with noninvasive breast cancer
2. Noninvasive combination technique may reduce number of breast biopsies
3. New research shows innovative respiratory stress test can quickly detect significant coronary artery disease in a noninvasive setting
4. New Insights on Who Should Take Erbitux for Colon Cancer
5. Mammogram Visit a Good Time to Arrange Colonoscopy: Study
6. Virtual colonoscopy option could improve colorectal cancer screening rates, patient survey suggests
7. Virtual colonoscopy and teleradiology bring colorectal cancer screening to patients in rural areas
8. Prostate cancer patients are at increased risk of precancerous colon polyps
9. Colonoscopy technique increases polyp detection in far reaches of right colon
10. Most Doctors Dont Follow Colon Cancer Screening Guidelines
11. Low-Dose Aspirin May Reduce Colon Cancer Risk
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Noninvasive Test for Colon Cancer Shows Promise in Early Trial
(Date:12/17/2014)... -- Expectant parents should leave prenatal picture-taking to medical ... Use of ultrasound imaging and heartbeat monitors to get ... agency warns. "Although there is a lack ... and heartbeat monitors, prudent use of these devices by ... FDA biomedical engineer, said in an agency news release. ...
(Date:12/17/2014)... HealthDay Reporter , TUESDAY, Dec. 16, ... America, and work commitment is a big reason why, new ... said Dr. Mathias Basner, an assistant professor of sleep and ... of Medicine. A time-use survey of nearly 125,000 Americans, ... main activity exchanged for sleep. Short sleepers -- those who ...
(Date:12/15/2014)... 15, 2014 South Florida’s leading urgent care ... can be a daze of hassle, hustle, and bustle that ... decking halls, to burns when making special meals and heartburn ... can happen at any time. To prevent this season of ... made a list of helpful and healthful holiday tips to ...
(Date:12/15/2014)... News) -- Expert pilots process visual information more efficiently ... better decisions during landings, a new study shows. ... pilots to master, and 36 percent of all airplane ... final approach and landing. Researchers monitored the brain ... pilots while they were at the controls of a ...
(Date:12/15/2014)... 15, 2014 At the leading, long-established ... AutismOne and Focus Autism will welcome ... research on the effects of toxins to children’s health, ... information. , Luminaries such as Dr. Lucija Tomljenovic ... with esteemed, credentialed colleagues of the United States to ...
Breaking Medicine News(10 mins):Health News:FDA Warns Against Fetal 'Keepsake' Videos 2Health News:Work Steals Valuable Sleep Time, Study Finds 2Health News:Work Steals Valuable Sleep Time, Study Finds 3Health News:MD Now Urgent Care Presents Healthy Holiday Tips 2Health News:MD Now Urgent Care Presents Healthy Holiday Tips 3Health News:Study Shows Why Expert Pilots Are Experts 2Health News:AutismOne and Focus Autism Collaborate on Scientific Conference; International Group of Researchers to Present in Chicago, May 2015 2Health News:AutismOne and Focus Autism Collaborate on Scientific Conference; International Group of Researchers to Present in Chicago, May 2015 3
... -- About 14 percent of strokes happen while people are ... to the hospital in time for a potentially brain-saving treatment, ... for ischemic stroke must be given within a few hours ... stroke symptoms often can,t receive the treatment since we can,t ...
... new to adolescents, researchers and physicians at Nationwide Children,s ... that is raising some concern among medical professionals. Often ... form of self-injurious behavior that involves inserting foreign objects ... into muscle. A recent study, published in the June ...
... prevalence of overall cardiovascular risk in the Spanish working population ... (8% on men and 2% in women). This prevalence increases ... farming sector, followed by construction, industry and services. "In ... of cardiovascular risk, but only a minority of these people ...
... ROCHESTER, Minn. - Constipation is definitely not a glamorous ... and costs more than $1 billion annually to evaluate ... bloating, discomfort, and straining associated with constipation lead sufferers ... researchers recently had success in the clinical trial of ...
... By Steven Reinberg HealthDay Reporter , MONDAY, May ... associated with a lethal nervous system disease known as amyotrophic ... explain, however, that this does not mean people with long ... they are at higher risk for it. "We have ...
... of U.S. veterans ages 70 and older finds that the ... methods. However, for many less healthy veterans the burdens of ... we really need to target screening in older adults, so ... while those who won,t benefit aren,t exposed to unnecessary burdens," ...
Cached Medicine News:Health News:Research Suggests 1 in 7 Strokes Happens During Sleep 2Health News:A new study on self-injury behavior encourages quick and targeted intervention 2Health News:6 percent of Spanish workers have high cardiovascular risk 2Health News:Mayo Clinic researchers find new treatment for constipation 2Health News:Ring Finger Length Linked to ALS, Study Suggests 2Health News:Ring Finger Length Linked to ALS, Study Suggests 3Health News:Blood test for colon cancer screening beneficial for some seniors, but not for many others 2
(Date:12/15/2014)... DUBLIN , Dec. 12, 2014 Research and ... ( http://www.researchandmarkets.com/research/ms3j8c/cardiac ) has announced the ... Estimates and Forecasts, 2012-2018"  report to their offering. ... by 2016. The North America ... while Europe claims approximately 25% ...
(Date:12/15/2014)... and HERZLIYA PITUACH, Israel , Dec. ... IMNP ) announced today that its Board of ... succeeding Dr. Daniel Teper who continues as Chief ... of Immune,s Board of Directors since 2013. Immune,s ... delighted to represent the interest of shareholders and to continue ...
(Date:12/15/2014)... BRIDGEWATER, N.J. , Dec. 15, 2014   ... SAN and NYSE: SNY) are collaborating with nationally-recognized patient ... Counts , an awareness program that will gauge how ... risks associated with high LDL-C (bad cholesterol).  American adults ... to take a brief poll and answer a few ...
Breaking Medicine Technology:Cardiac Guidewires - Global Trends, Estimates and Forecasts, 2012-2018 2Cardiac Guidewires - Global Trends, Estimates and Forecasts, 2012-2018 3Cardiac Guidewires - Global Trends, Estimates and Forecasts, 2012-2018 4Immune Pharmaceuticals Elects Daniel Kazado as New Chairman of the Board. 2Immune Pharmaceuticals Elects Daniel Kazado as New Chairman of the Board. 3Immune Pharmaceuticals Elects Daniel Kazado as New Chairman of the Board. 4Have You Been Counted? Regeneron and Sanofi US Join Forces with Leading Cardiovascular Organizations to Raise Awareness of Cholesterol 2Have You Been Counted? Regeneron and Sanofi US Join Forces with Leading Cardiovascular Organizations to Raise Awareness of Cholesterol 3Have You Been Counted? Regeneron and Sanofi US Join Forces with Leading Cardiovascular Organizations to Raise Awareness of Cholesterol 4Have You Been Counted? Regeneron and Sanofi US Join Forces with Leading Cardiovascular Organizations to Raise Awareness of Cholesterol 5Have You Been Counted? Regeneron and Sanofi US Join Forces with Leading Cardiovascular Organizations to Raise Awareness of Cholesterol 6
... PRUSSIA, Pa., May 1, 2012  Medical Alarm Concepts Holding, ... agreement with several holders of its convertible debt. Under ... has been cancelled, preventing a significant amount of common ... of another 13,750,000 million warrants, bringing the total number ...
... Acella Pharmaceuticals, LLC, announces the addition of Tom ... of their commercial team. Tom will lead the ... line.    Tom is a highly ... than 11 years of industry experience, including sales, ...
Cached Medicine Technology:MDHI in Agreement with Debt Holders - Portion of Convertible Debt and Additional 14M Warrants Cancelled -- Total of 101M Warrants Cancelled this Year 2
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: