Navigation Links
Non-Polyp Colon Lesions Hard to Detect
Date:3/4/2008

These flat growths are relatively common and tend to be cancerous, study finds,,,,

TUESDAY, March 4 (HealthDay News) -- While the majority of colon cancers were thought to develop from polyps, a new study challenges that assumption and points out that so-called non-polypoid (flat or depressed) lesions in the colon are also likely to turn into cancer.

A study in the March 5 issue of the Journal of the American Medical Association reports that such lesions were present in almost 10 percent of people screened for the study, and that these lesions were 10 times more likely to be cancerous than polyps were.

"Colorectal cancer is common, it is preventable, and it can be prevented even better," said the study's lead author, Dr. Roy Soetikno, chief of gastroenterology at the Veterans Affairs Palo Alto Health Care System in California. "Not all colon cancers are created equal, and doctors will now start looking for those that aren't so obvious."

Soetikno said it's like when you cross the street: You look left, and you look right before you cross, but "you never look carefully for the pothole on the street. This study is saying that doctors need to look at everything, including the potholes, to do a much better job."

The good news is that with current colonoscopy technology, doctors can find and remove these lesions. The bad news is that virtual colonoscopy (CT colonography) is not yet sensitive enough to pick up these dangerous lesions.

Previously, experts believed that these non-polypoid lesions were mainly found in people of Japanese descent, and U.S. doctors weren't specially trained to look for them. Soetikno and his colleagues underwent special training with specialists from Japanese endoscopy centers to learn to better detect these potentially pre-cancerous lesions.

Using their new knowledge, the U.S. researchers searched for non-polypoid lesions among 1,819 veterans who were already scheduled to undergo standard colonoscopy. The average age of the study participants was 64, and 95 percent were male. And, most -- 79 percent -- were white.

The researchers found that 764 people (42 percent) had at least one unusual colorectal growth. One hundred and seventy (9.35 percent) had non-polypoid colorectal lesions. Eighty-one of these people had both polyps and non-polypoid lesions.

Soetikno said that in a general screening, the chance of finding a polyp is about 30 percent, and that doctors are about five times more likely to find polyps than non-polypoid lesions. But, non-polypoid lesions are far more likely to be cancerous than polyps are. The new study found the odds were 9.78 times higher that a non-polypoid lesion would be cancerous than a polyp.

Generally, non-polypoid lesions can be removed at the time of a colonoscopy. If the center where you have your colonscopy done doesn't have the expertise yet, you may have to undergo a second procedure to have the lesion removed. Also, Soetikno said that if the lesion is completely flat, you'll probably need to go to a more experienced center to have it removed.

Dr. David Lieberman is chief of the division of gastroenterology at Oregon Health and Science University and the Portland VA Medical Center, and author of an accompanying editorial in the journal. He said, "I think this study will be very enlightening for the [gastroenterology] community. It points out that the non-polypoid lesions are found in the U.S., and that they can be somewhat ominous because they carry a reasonably high risk of cancer."

Both Soetikno and Lieberman stressed that this study's findings don't mean that a colonoscopy isn't useful. It definitely is, at both screening for and preventing colorectal cancer, the second leading cause of cancer death in the United States.

"Colonoscopy is a very good tool. It's not perfect, but it's a good tool," Lieberman said. "This study emphasizes the need for a high-quality examination with a fully-trained endoscopic technician," he added.

More information

To learn more about colonoscopy, visit the American Gastroenterological Association.



SOURCES: Roy M. Soetikno, M.D., M.S., chief of gastroenterology, Veterans Affairs Palo Alto Health Care System, California; David Lieberman, M.D., professor of medicine, and chief, division of gastroneterology, Oregon Health and Science University, Portland; March 5, 2008, Journal of the American Medical Association


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. SGV Medical Supplies: Colostomy Supplies Easier to Obtain for the Colon Cancer Survivor
2. Mouse study: Real-time imaging device may improve surgery for congenital colon disease
3. Earlier Colon Cancer Screens Urged for Smokers
4. What are simple ways to judge the efficacy of 5-fluorouracil in colonic neoplasm?
5. A rare diagnosis in the operation room: Kidney atrophy due to duplicated colon in an adult
6. In Combination With FOLFOX4, the Effect of Erbitux and Avastin On Survival Rates Will Drive Prescription Decisions in the Treatment of Stage III Colon Cancer
7. US cancer deaths down but far too few Americans screened for colon cancer
8. U.S. Cancer Deaths Down But Far Too Few Americans Screened for Colon Cancer
9. The Facts African Americans Need to Know About Colon Cancer
10. Smokers might benefit from earlier colon cancer screening
11. Colonial Life Goes One On One With ESPN
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/9/2016)... ... February 09, 2016 , ... URise Products ... newest mobility device, the StandUp Walker. Made entirely in the USA, the StandUp ... 50 years. , StandUp Walker’s novel patent-pending design offers 2-in-1 benefits of ...
(Date:2/9/2016)... ... 2016 , ... Establishment Labs, a global breast implant and medical technology company, ... of Directors. , “We are honored to welcome David to our Board ... Jose Chacon Quiros, CEO of Establishment Labs. "David’s knowledge and experience will be invaluable ...
(Date:2/9/2016)... ... February 09, 2016 , ... ... service to expand access to affordable hearing aids , increase industry transparency, ... individuals in the United States. , “For the average consumer, the hearing aid ...
(Date:2/9/2016)... (PRWEB) , ... February 09, 2016 , ... ... grout cleaning and sealing company , is proud to announce that many of ... superior levels of customer service. The hard surface restoration franchises received customer recognition ...
(Date:2/8/2016)... (PRWEB) , ... February 08, 2016 , ... ... launched its newly redesigned website, federallabs.org . The site houses a wealth ... license available federal technologies through the process called technology transfer (T2). As a ...
Breaking Medicine News(10 mins):
(Date:2/9/2016)... 2016 The new report "Global Blood Monitoring & Cardiac Monitoring Devices ... Consulting group reveals that global market for blood monitoring & cardiac ... expected to grow to US$ 24,830.1 million by 2019 at a ... America , Europe , Asia-Pacific ... and Africa . The three major ...
(Date:2/9/2016)... , Feb. 9, 2016  Johnson & Johnson ... Capital Markets Global Healthcare Conference on Tuesday, Feb. 23, ... Dominic Caruso , Vice President, Finance & Chief ... Consumer will represent the Company in a session scheduled ... . --> www.investor.jnj.com . --> ...
(Date:2/9/2016)... , Feb. 9, 2016  Bluestar Silicones will ... product line for long-term implant applications and announce ... Design & Manufacturing (MD&M) West Conference (Booth #1759), ... --> --> Available ... Biomedical LSRs offer outstanding physical properties enabling our ...
Breaking Medicine Technology: