Navigation Links
Non-AIDS-Related Cancers Growing Among HIV Patients
Date:9/30/2009

Possible reasons for increased rates explored by researchers

WEDNESDAY, Sept. 30 (HealthDay News) -- Non-AIDS-related cancers such as anal and lung cancer have become more common among HIV patients than among people without HIV since antiretroviral therapies were introduced in the mid-1990s to treat people with the virus, U.S. researchers say.

Because of their weakened immune system, AIDS patients are at increased risk for so-called AIDS-defining malignancies, which include cancers such as cervical carcinoma, non-Hodgkin's lymphoma and Kaposi's sarcoma.

There has been speculation that non-AIDS-defining malignancies are becoming more common among HIV patients because antiretroviral drugs help them live longer. But this new study by researchers at University of Texas Southwestern Medical Center in Dallas suggests other factors may exist.

The researchers analyzed 1997 to 2004 data from more than 100,000 patients in the U.S. Veterans Affairs Healthcare System and found that HIV-infected patients were 60 percent more likely to have anal, lung, Hodgkin's, melanoma or liver cancer than patients without HIV.

"It's a genuine increase in the incidence of these cancers," lead author Dr. Roger Bedimo, an assistant professor of internal medicine, said in a university news release. "The increase is more visible because these patients are living longer, but our findings suggest that the increased number of non-AIDS-defining malignancies is not simply the result of their longer lives."

The study appears online and in the October print issue of the Journal of Acquired Immune Deficiency Syndromes.

One controversial theory is that antiretroviral therapy itself may increase the risk of non-AIDS-defining malignancies, the study authors noted.

"The second hypothesis is that HIV-infected patients somehow, either by their lifestyle or other circumstances, are more subject to the traditional risk factors than non-HIV patients," Bedimo said. "The third hypothesis is that HIV or another undetected virus increases a patient's risk for developing cancer intrinsically."

More information

The U.S. National Cancer Institute has more about AIDS-related cancers.



-- Robert Preidt



SOURCE: University of Texas Southwestern Medical Center, news release, Sept. 25, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Certain cancers more common among HIV patients than non-HIV patients
2. Excess body weight causes over 124,000 new cancers a year in Europe
3. Virus May Drive Some Prostate Cancers
4. New Compound Shrinks Skin Cancers
5. Blood Flow Mismatch Seen in Pancreatic Cancers
6. HPV Vaccine Could Prevent Many Penile Cancers
7. How diarrheal bacteria cause some colon cancers revealed in mouse studies
8. Fecal DNA methylation detects gastric and colorectal cancers
9. Fox Chase researchers identify differences in treatments and outcomes of patients with second primary lung cancers versus those with one primary lung cancer
10. AIDS patients face higher risk of HPV-related cancers as immunosuppression grows
11. Rare Cells Linked to Pediatric Cancers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2017)... ... May 23, 2017 , ... Cambridge, MA, ... steady since 2009, according to a Workers Compensation Research Institute (WCRI) study, a ... the North Carolina System: CompScope™ Benchmarks, 17th Edition looks at indemnity and ...
(Date:5/23/2017)... Santa Rosa, California (PRWEB) , ... May 23, ... ... population health management (PHM) technology and a 2017 Best in KLAS category winner, ... an advantageous market position to extend and enhance its technology platform and product ...
(Date:5/23/2017)... ... , ... London, May 23, 2017: Walter Schindler, the Founder and Managing Partner ... Speaker and Contributor to a weeklong series of classes, meetings, field trips and special ... Walter Schindler and SAIL Capital have received an increasing number of ...
(Date:5/23/2017)... (PRWEB) , ... May 23, 2017 , ... By all ... underway in Sonoma County. While officials call for diligence, asking homeowners to scout for ... at potential health concerns. Along with the annoying buzz of mosquitos is the buzz ...
(Date:5/23/2017)... ... May 23, 2017 , ... MedTech For ... the modern ART laboratory, to provide hands-on training utilizing cutting-edge equipment at its ... LifeLabs, a MedTech Group Purchasing vendor , will provide specialized equipment to ...
Breaking Medicine News(10 mins):
(Date:5/10/2017)... -- Hologic, Inc. (Nasdaq: HOLX ) announced ... quarter ended April 1, 2017 .   GAAP diluted ... to the prior year period as the sale of ... while non-GAAP diluted EPS of $0.50 increased 6.4%.  Revenue ... currency terms.  Excluding the effects of blood screening and ...
(Date:5/10/2017)... Md. , May 10, 2017 CSSi, ... solutions for the clinical research industry, is proud to ... www.CSSiEnroll.com . The new website features both enriched content ... user experience and enhances the company,s already well-established position ... industry. "After many months of hard ...
(Date:5/9/2017)... PORTLAND, Ore. , May 9, 2017 /PRNewswire/ ... company that provides technology solutions to improve the ... reported financial results for the first quarter ended ... that our products enable our customers to identify ... them to intervene before events like heart attacks ...
Breaking Medicine Technology: