Navigation Links
Nobel laureates Brown, Goldstein to give inaugural Stadtman award lecture
Date:4/7/2011

BETHESDA, Md., April 7, 2011 The American Society for Biochemistry and Molecular Biology has named Nobel laureates Michael S. Brown and Joseph L. Goldstein, pioneers in the study of cholesterol metabolism, the joint winners of its first Earl and Thressa Stadtman Distinguished Scientist Award.

Brown and Goldstein will present their award lecture, "The SREBP Pathway: Stadtman's Paradigm Applied to Cholesterol," at 2:40 p.m. April 11 at the Experimental Biology 2011 Conference at the Walter E. Washington Convention Center.

Ira Pastan of the National Cancer Institute, who nominated the pair for the award, says their "sustained record of joint discoveries places them at the forefront of regulatory biochemistry, the field that was pioneered by Earl Stadtman."

Brown and Goldstein, both of the University of Texas Southwestern Medical Center at Dallas, shared the 1985 Nobel Prize in medicine or physiology for their discovery of the low-density lipoprotein, or LDL, receptor and the process of receptor-mediated endocytosis. In recent years, they discovered sterol regulatory element-binding proteins and the process of regulated intramembrane proteolysis.

"Joe and Mike are towering intellects and leaders in the field of biomedical sciences," says Phillip Sharp, a professor at the Koch Institute for Integrative Cancer Research at the Massachusetts Institute for Technology. "They are among the most recognized and celebrated scientists of their generation and remain active, producing excellent science on contemporary topics."

The researchers met at Massachusetts General Hospital in Boston in the 1960s and have collaborated ever since. From 1968 to 1971, Brown worked at the National Institutes of Health, initially as a clinical associate in gastroenterology and hereditary disease and later in the biochemistry laboratory headed by Earl Stadtman himself. Meanwhile, Goldstein spent 1968 through 1970 at the NIH as well, working in the laboratory of Marshall W. Nirenberg and at the National Heart Institute.

In 1971, Brown joined the University of Texas Southwestern Medical School in Dallas. A year later, so did Goldstein. (It's worth noting that Goldstein had attended medical school there, so, for him, it was a homecoming of sorts.)

"Put simply, these guys are great. It has been a pleasure for the scientific community to watch this story unfold," says Richard Axel, a professor at Columbia University Medical Center and the recipient of the 2004 Nobel Prize in physiology or medicine. "With unabated and unsurpassed creativity and rigor, they continue to pursue a problem in basic science with profound implications for clinical medicine: the regulation of lipid and cholesterol biosynthesis."

Robert D. Simoni, chairman of the biology department at Stanford University and associate editor of the Journal of Biological Chemistry, emphasizes that Brown and Goldstein also have kept alive the Stadtmans' tradition of mentoring.

"Beyond their own research accomplishments, Mike and Joe, like the Stadtmans, have provided an excellent training ground for young scientists, many of whom have gone on to assume leadership roles in biochemistry," Simoni says.

The Stadtman award was established by friends and colleagues to preserve their legacies as scientists and mentors. It is awarded to an established scientist for his or her outstanding achievement in basic research in the fields encompassed by the ASBMB. The award is given every other year, alternating with The Earl and Thressa Stadtman Young Scholar Award. The distinguished scientist award consists of a plaque, a $10,000 purse and travel expenses to present a lecture at the ASBMB annual meeting.


'/>"/>

Contact: Angela Hopp
ahopp@asbmb.org
301-634-7389
American Society for Biochemistry and Molecular Biology
Source:Eurekalert  

Related medicine news :

1. 2010 Chemistry Nobel laureate Ei-ichi Negishi leads C&EN webinar
2. Medicinal chemist wins inaugural De Burgh Fellowship
3. SC Magazine Strengthens Commitment to Canadian Information Security with Inaugural SC Congress Canada
4. Steve Waugh To Launch Inaugural Men's Health Screening Event In Wollongong
5. Dr. Kessler, Congressman Price & Mayo Clinic Headline Inaugural MDPA Conference
6. MEDIA ADVISORY: Let's Move L.A. Inaugural Event and Launch Party. April 28th, 2010. 11am - 2pm.
7. American Cancer Society's Inaugural Starry Night Gala Premiers at Trump National Golf Club
8. BestofNorthCarolina.com Presents Their Inaugural 'Carolina Beach Bash' to Benefit the Juvenile Diabetes Research Foundation
9. American Cancer Society's Inaugural Starry Night Gala Premiers at Trump National Golf Club
10. Cambridge Healthtech Announces Its Inaugural Encouraging Development of Therapeutics for Neglected Diseases Conference
11. Winners are Grinners at the Inaugural Parallels Partner Awards
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Nobel laureates Brown, Goldstein to give inaugural Stadtman award lecture
(Date:12/8/2016)... Reston, Virginia (PRWEB) , ... December 08, 2016 ... ... and services company offering Medication Therapy Management (MTM), adherence, and other pharmacist-delivered patient ... of operations and general counsel and Eric Hoessel to vice president of sales. ...
(Date:12/8/2016)... ... , ... Premier Fitness Camp (PFC) and The Chopra Center for Wellbeing announced ... program, at their world headquarters of Omni La Costa Resort & Spa in San ... seeking weight loss, personal development, a healthy lifestyle, or mental and physical healing. The ...
(Date:12/8/2016)... (PRWEB) , ... December 08, 2016 , ... ... Medical Center has been recognized for adherence to the highest standards of ... medical accreditation organizations, announced the center's president and CEO, Dr. Daniel Messina. , ...
(Date:12/8/2016)... NC (PRWEB) , ... December 08, 2016 , ... ... Medicare and the Affordable Care Act. Dr. Botelho advocates for the mass media ... story movement gives people ongoing opportunities to share their unfortunate experiences; such a ...
(Date:12/8/2016)... ... December 08, 2016 , ... ... services from offices headquartered in Jefferson County, is announcing the launch of a ... Birmingham. , The number of homeless women and children in Birmingham has grown ...
Breaking Medicine News(10 mins):
(Date:12/8/2016)... SAN DIEGO , Dec. 8, 2016 /PRNewswire/ ... with cutting edge next-generation sequencing and bioinformatics expertise; AITbiotech Pte ... the Genome Institute of Singapore (GIS) ... joint venture between Novogene and AITbiotech – will establish a ... Singapore .   The new centre will ...
(Date:12/8/2016)... -- Eli Lilly and Company (NYSE: LLY ... a cyclin-dependent kinase (CDK) 4 and CDK 6 inhibitor, ... a biomarker of cell proliferation, after two weeks of ... during the official press program at the 2016 San ... or in combination with the non-steroidal aromatase-inhibitor anastrozole, in ...
(Date:12/7/2016)... Dec. 7, 2016 KEY FINDINGS ... benefits such as reducing loss of blood during ... cardiac arrests, rapid recovery after surgeries, and decreasing ... be segmented into convective warming system, surface warming ... turn reduce the stay at hospitals thus, lowering ...
Breaking Medicine Technology: