Navigation Links
No link between genetic ancestry, asthma response in African-Americans
Date:9/27/2010

DETROIT Genetic ancestry has no discernible influence on how African American patients with asthma respond to medication, according to a Henry Ford Hospital study.

Researchers found that improved lung function in patients after taking inhaled steroids was related to a series of baseline breathing function measures, not genetic ancestry. The study is published online at the Journal of Allergy & Clinical Immunology, http://www.aaaai.org/media/jaci/

Advances in genetics have led to the development of ancestry markers spread across the human genome, which allow genetic ancestry to be easily and inexpensively estimated among African Americans. It has the potential to be a useful tool in predicting the severity of common conditions among African Americans and fostering the development for more personalized medicine.

"However, our study found that genetic differences due to ancestry probably contributed to little, if any, difference in how African Americans responded to inhaled corticosteroids," says Wendy Gould, M.D., the study's lead author and a fellow in Allergy & Immunology at Henry Ford Hospital.

More than 20 million Americans, or approximately 1 in 15, suffer from asthma, which accounts for nearly 500,000 hospitalizations in the United States annually, according to the American Academy of Allergy, Asthma and Immunology. African Americans appear to be especially prone to asthma and its complications, which result in more frequent emergency department visits and hospitalizations when compared with white individuals.

Because of that susceptibility, Henry Ford researchers set out to determine what role, if any, genetic ancestry plays in how well African Americans respond to inhaled corticosteroids, which is considered the most effective class of medication for controlling asthma.

Researchers followed 147 African-American asthma patients aged 12-56 who wer
'/>"/>

Contact: David Olejarz
dolejar1@hfhs.org
313-874-4094
Henry Ford Health System
Source:Eurekalert

Page: 1 2

Related medicine news :

1. UC Davis scientists find link between arthritis pain reliever and cardiovascular events
2. Study examines association between urban living and psychotic disorders
3. Pivotal study finds link between PTSD and dementia
4. Scientists find link in humans between nerve cell production, memory
5. Penn study sheds light on how the brain shifts between sleep/awake states under anesthesia
6. Link Between Diabetes, Alzheimers Disease Strengthened
7. Study Suggests Link Between Diet Sodas, Preterm Delivery
8. New study finds new connection between yoga and mood
9. VCU Massey research finds new link between inflammation and cancer
10. Sex between adolescents in romantic relationships is often harmless to their academics
11. New Data Supports Link Between Diabetes Drugs, Fractures
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/9/2014)... researchers reveal that sudden, acute episodes of low back ... temperature, humidity, air pressure, wind direction and precipitation. Findings ... journal of the American College of Rheumatology (ACR), indicate ... with higher wind speed or wind gusts, but was ... Health Organization (WHO) nearly everyone experiences low back pain ...
(Date:7/9/2014)... A network of signals active in almost all types ... into overdrive, and may help fuel a tumour,s uncontrolled ... of Cancer Research, London, identified a molecular trigger responsible ... the cellular factory that makes the building blocks ... in the TOR signalling pathway, called SREBP, controls the ...
(Date:7/9/2014)... fecal transplantation is effective and safe for treating ... result of a study led by Colleen Kelly, M.D., ... at The Women,s Medicine Collaborative. The study and its ... in the American Journal of Gastroenterology . , ... has increased to epidemic proportions over the past decade. ...
(Date:7/9/2014)... 9, 2014 There has been a sharp increase ... Medical Center using MyChart, the online, interactive service that ... with their healthcare providers, schedule appointments, and renew prescriptions. ... actively using MyChart each year increased five-fold, ... more than 10-fold, according to a study by ...
(Date:7/9/2014)... Infectious Diseases (NIAID), part of the National Institutes ... of CRS3123, an investigational oral antibiotic intended to ... ) infection. CRS3123 (previously known as REP3123) is ... while sparing normal intestinal bacteria. , The Phase ... men and women ages 18 to 45 in ...
Breaking Medicine News(10 mins):Health News:Low back pain? Don't blame the weather 2Health News:Signal may send cancer's cellular factories into overdrive 2Health News:Women's Medicine Collaborative examines safety of fecal transplant to treat C. difficile 2Health News:MyChart use skyrocketing among cancer patients, UT Southwestern study finds 2Health News:MyChart use skyrocketing among cancer patients, UT Southwestern study finds 3Health News:NIH launches Phase I clinical trial of novel drug to treat Clostridium difficile infection 2
... and in the care of state institutions, should be ... and treatment, Health// Minister Manto Tshabalala-Msimang said. ... members, at Weskoppies psychiatric hospital, Pretoria, the minister said ... the past that mental health care users could be ...
... access journal Substance Abuse Treatment, Prevention and policy unwinds that ... the alcohol dependent patients better for a long term. ... GPs who abstain from drinking alcohol is more than the ... alone at the medical school. Also the abstinence is ...
... Post Menopausal women with early breast cancer who have ... to a more modern therapy with the drug//, Arimidex ... AstraZeneca. ,The company AstraZeneca has stated that ... women who have already received a partial course of ...
... death of 113 animals associated with the anthrax outbreak ... in Saskatchewan. Spore-forming bacteria that can spread// among animals ... anthrax. ,The Canadian Food Inspection Agency (CFIA) ... animals on farms tested positive for anthrax. However some ...
... claims to have reached, and exceeded, its medical recruitment ... the need// for an additional $5 billion for mental ... planned to employ400 more allied health professionals, 500 more ... ,According to Health Minister Stephen Robertson the ...
... their new studies have concluded that persons who live ... serious heart condition when compared to people// who live ... Melgaard Nielsen, Ph.D., and colleagues, of the Aarhus Sygehus ... on 138,000 adults between the ages of 30-69. Their ...
Cached Medicine News:Health News:Queensland Government to Meet its Medical Targets 2Health News:Significant Increase In Heart Diseases Found In Older People Living Alone 2
(Date:1/15/2014)... , Jan. 15, 2014  A novel wearable injector slightly larger ... painless for patients to self-inject prescription drugs in the large ... cancer, blood diseases, autoimmune deficiencies, and genetic disorders.  ... to $220B by 2018, according to analysts.   Many of these ...
(Date:1/14/2014)... HILLS, Calif. , Jan. 14, 2014 The Brandeis Medical ... Los Angeles a premier and affordable laser tattoo removal ... special. Dr. Brandeis, focus is in providing high quality cosmetic services ... all patients. " Southern California has ...
(Date:1/14/2014)... 14, 2014   NuAire , a manufacturer of ergonomically designed ... Hitachi Koki of Japan to sell ... America . NuAire will utilize its network of sales professionals ... Canada to offer assistance in application use, product benefits ...
Breaking Medicine Technology:Enable Injections Presents A New Class of Injectors for Drug Delivery at PEPTalk, Drug Delivery Partnership Meetings 2Beverly Hills Physician Features Tattoo Removal with the Astanza Duality Laser, Offers $99 Special 2NuAire announces sales and service of Hitachi Koki centrifuges in North America 2
... N.C., Oct. 31 AlphaVax, Inc.,announced today that it ... of an influenza vaccine based on its proprietary replicon ... properties of this,unique vector system as well as the ... was a placebo-controlled, randomized, double-blind trial in,healthy adults, 18-40 ...
... guide low-income,and minority cancer patients through cancer treatment, ... major obstacles that prevent them,from receiving quality care ... October 28, 2007, at the American Society for ... Angeles. Minority and low-income cancer patients continue ...
Cached Medicine Technology:AlphaVax Announces Results From Phase 1 Influenza Vaccine Clinical Trial 2Patient Navigators Help Minority, Low-Income Cancer Patients Get Life-Saving Treatments 2
... generators are meeting the clinical needs ... and anesthesiologists. And, they are of ... from Medtronic.,Effective pacing with the adjustment ... for quick battery changes. Both ...
... CardioVad is a unique left ventricular assist device ... It is being used in a small group ... as part of an FDA-approved Feasibility Study. The ... the external power source for minutes or hours. ...
... Inc. has introduced the world's first minimally-invasive ... 10626 Epicardial Lead Implant Tool, which has ... States, will expand the options available to ... 5071 lead on the heart during pacemaker ...
The Schiller treadmill ergometer is designed for stress tests, sports medicine and cardiology. It is equipped and tested with the latest safety system and has been manufactured under the stringent qu...
Medicine Products: