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No increase in commonest preventable cause of intellectual disability over 20 years
Date:7/18/2011

to a provincial database over a period of 20 years, the results from the detection and diagnosis of 620 cases of CH could be analyzed.

Details about the study:

Historical data were analyzed for the study jointly with the Qubec newborn blood screening laboratory located at the Centre hospitalier universitaire de Qubec (CHUQ). More precisely, of the 1,660,857 newborns tested over the 20-year period, 620 cases of CH were detected, diagnosed and treated. During the second half of the period, a slightly more sensitive detection threshold was applied in addition to those expected, 49 further cases of CH were detected, representing an 18 % increase. Most of these additional cases had mild functional disorders whose impact on mental development is uncertain. Most importantly, the number of detected cases would have remained stable throughout the period studied if the screening threshold had been unchanged.

The study was published ahead of print on June 1, 2011 in the Journal of Clinical Endocrinology and Metabolism by Dr. Johnny Deladoey of the CHU Sainte-Justine Research Center and University of Montreal, jointly with Dr. Guy Van Vliet, also of the CHU Ste-Justine, and Dr. Jean Ruel and Dr. Yves Gigure, of the Qubec newborn blood screening laboratory at the CHUQ.


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Contact: William Raillant-Clark
w.raillant-clark@umontreal.ca
514-343-7593
University of Montreal
Source:Eurekalert

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