Navigation Links
No increase in cardiovascular risk for living kidney donors
Date:11/3/2007

Living kidney donors show no increase in their risk of heart attacks or other cardiovascular events in the years after donation, according to the largest-ever study of the issue, being presented at the American Society of Nephrology's 40th Annual Meeting and Scientific Exposition in San Francisco.

Although donors are more likely to be diagnosed with high blood pressure (hypertension) during follow-up, it is unclear whether this represents a true risk of living kidney donation, according to Lawson Health Research Institute scientist, Dr. Amit X. Garg. Dr. Garg is also an Associate Professor in Medicine and Epidemiology with the Schulich School of Medicine & Dentistry at The University of Western Ontario in London, Ontario, Canada.

Dr. Garg and colleagues analyzed follow-up data on 1,278 patients who became living kidney donors in Ontario between 1993 and 2005. Rates of major cardiovascular eventsincluding myocardial infarction (heart attack), stroke, angioplasty, or bypass surgerywere compared to those of 6,369 healthy adults. To ensure comparability, the two groups were closely matched for age, sex, income, and use of health care services before donation.

During a follow-up period of one to thirteen years (average six years), 1.3 percent of the living kidney donors died or experienced a cardiovascular event. This was not statistically different from the 1.7 percent rate in the comparison group.

The only significant difference was a higher rate of hypertension among living kidney donors: about 16 percent, compared with 12 percent in the comparison group. "Donors were diagnosed more frequently with hypertension, but they also saw their primary care physicians more often than controls, and so had more opportunities to be diagnosed," says Dr. Garg. On average, the donors had one additional medical visit per year.

Living kidney donation has become an important source of organs for transplantation. However, it is essential to know the extent and nature of any health risks of donation. "Knowledge of any potential risks associated with becoming a living kidney donor would guide future donor selection, informed consent, and best practices to follow and care for living donors," comments Dr. Garg. "Risk estimates in the literature are currently quite variable, and there is global consensus that we need better estimates."

The new study refines past estimates by providing long-term follow-up data on a large group of living kidney donors50 times larger than any previous study. Encouragingly, the results show no long-term increase in cardiovascular risk after donation.

Further study is needed to determine whether the apparent increase in the risk of high blood pressure is truly an effect of living kidney donation, or if it merely reflects the increased medical scrutiny after donation. "These results emphasize the importance to counsel and follow all kidney donors to manage modifiable factors in an attempt to prevent hypertension and future cardiovascular disease," adds Dr. Garg.


'/>"/>

Contact: Shari Leventhal
sleventhal@asn-online.org
202-558-8423
American Society of Nephrology
Source:Eurekalert

Related medicine news :

1. Use of Cellular Phones associated with Increased risk of Brain Tumors
2. Mortality increased in Sporting enthusiasts!
3. Tattoos may significantly increase risk of hepatitis C infection
4. Increase in sugar...decrease in brain function!!!
5. Increase in tobacco deaths
6. Increased Heart Attack Risk From Celebrex,Vioxx
7. Increase in drug abuse by teenagers
8. Increase in the Number of Cases of Animal Diseases in New South Wales.
9. Metronidazole Increases Risk Of Premature Deliveries.
10. Hepatitis A Cases On A Steady Increase In Canterbury
11. Human gene number increases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... , ... June 26, 2016 , ... ... once they have been diagnosed with endometriosis. These women need a treatment plan ... require a comprehensive approach that can help for preservation of fertility and ultimately ...
(Date:6/25/2016)... ... 2016 , ... First Choice Emergency Room , the largest network of ... Medical Director of its new Mesquite-Samuell Farm facility. , “We are pleased to ... said Dr. James M. Muzzarelli, Executive Medical Director of First Choice Emergency Room. ...
(Date:6/24/2016)... Los Angeles, CA (PRWEB) , ... June 24, 2016 , ... ... plastic surgery procedures that most people are unfamiliar with. The article goes on to ... known procedures, but also many of these less common operations such as calf and ...
(Date:6/24/2016)... MIAMI, Fla. (PRWEB) , ... June 24, 2016 , ... ... Florida Trend magazine’s 2016 Legal Elite. The attorneys chosen by their peers for this ... of Florida. , Seven Greenberg Traurig Shareholders received special honors as members of this ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... the Clinical Decision Making in Emergency Medicine conference in Ponte Vedra Beach, FL. ... articles published in Emergency Medicine Practice and Pediatric Emergency Medicine Practice. ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 Research and ... Global Market - Forecast to 2022" report to their ... treatment method for the patients with kidney failure, it replaces ... fluid from the patient,s blood and thus the treatment helps ... and chloride in balance. Increasing number of ...
(Date:6/23/2016)... , June 23, 2016 Roche (SIX: ... 510(k) clearance for its Elecsys BRAHMS PCT (procalcitonin) assay ... sepsis or septic shock. With this clearance, Roche is ... a fully integrated solution for sepsis risk assessment and ... with bacterial infection and PCT levels in blood can ...
(Date:6/23/2016)... -- Bracket , a leading clinical trial technology and ... platform, Bracket eCOA (SM) 6.0, at the 52 nd ... 2016 in Philadelphia , Pennsylvania.  A demonstration ... of its kind to fully integrate with RTSM, will be ... is a flexible platform for electronic clinical outcomes assessments that ...
Breaking Medicine Technology: