Navigation Links
No evidence drugs, vitamins, supplements help prevent cognitive decline in healthy older adults
Date:4/15/2013

TORONTO, April 15, 2013A review of published research has found no evidence that drugs, herbal products or vitamin supplements help prevent cognitive decline in healthy older adults.

The review, conducted at St. Michael's Hospital, found some evidence that mental exercises, such as computerized memory training programs, might help.

"This review provides some evidence to help clinicians and their patients address what strategies might prevent cognitive decline," said Dr. Raza Naqvi, a University of Toronto resident and lead author of the review.

The issue is of particular importance given that mild cognitive impairment affects 10 to 25 per cent of people over age 70. Mild cognitive impairment is characterized by reduced memory, judgment, and decision-making skills compared to someone of a similar age, but not enough to interfere with daily activities.

The annual rate of decline into dementia, such as Alzheimer's disease, is about 10 per cent. Given that rate and the aging population, it's estimated the number of Canadians with dementia will double to more than 1 million in the next 25 years.

Researchers including Dr. Sharon Straus, head of the Knowledge Translation Program at St. Michael's, reviewed 32 randomized clinical trials involving about 25,000 patients.

They found no strong evidence for pharmacologic treatments such as cholinesterase inhibitors that were developed to improve the effectiveness of acetylcholine, a chemical messenger that assists memory, thought and judgment.

Nor was there strong evidence that herbal supplements such as gingko improved cognitive functions or vitamins and fatty acids such as vitamin B6 or omega-3 fatty acids.

Some studies on estrogen actually indicated an increase in cognitive decline and dementia.

Evidence on the value of physical exercise, such as strength-training, was weak.

The strongest evidence was for the value of mental exercises such as computerized training programs or intensive one-on-one personal cognitive training in memory, reasoning, or speed of processing.

Dr. Naqvi said future studies should address the impact of cognitive training on the prevention of cognitive decline.

"We encourage researchers to consider easily accessible tools such as crossword puzzles and sudoko that have not been rigorously studied," he said. "The studies in this review that assessed cognitive exercises used exercises that were both labour- and resource-intensive, and thus may not be applicable to most of our patients."


'/>"/>

Contact: Leslie Shepherd
shepherdl@smh.ca
416-864-6094
St. Michael's Hospital
Source:Eurekalert

Related medicine news :

1. More Evidence Shows Hormone Therapy May Increase Breast Cancer Risk
2. DrugRisk Update: Evidence Submitted in Actos Lawsuit Suggests Drug Maker Knew of Cancer Risks
3. New Analysis Says Evidence Lacking for HRT-Breast Cancer Link
4. Evidence supports blocking immune response to enhance viral therapy against solid tumors
5. More Evidence Whooping Cough Protection Wanes
6. First evidence that obesity gene is risk factor for melanoma
7. More Evidence That Smoking Raises Breast Cancer Risk
8. Evidence shows concussions require long-term follow-up for players
9. Review: Few effective, evidence-based interventions for children exposed to traumatic events
10. Reassuring evidence: Anticancer drug does not accelerate tumor growth after treatment ends
11. JSCM publishes issue on NIDRR-funded project on practice-based evidence in SCI rehabilitation
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2016)... (PRWEB) , ... May 23, 2016 , ... ... announce the participation of high-level representatives from the Japan PMDA, US FDA, industry ... will address how CDISC standards help format data from clinical trials so that ...
(Date:5/23/2016)... , ... May 23, 2016 , ... ... Texas Veterinary Medical Association (TVMA) reminds pet owners that intervening at the first ... Heatstroke occurs when a pet’s normal body mechanisms cannot keep the body’s temperature ...
(Date:5/23/2016)... Hollywood, California (PRWEB) , ... May 23, 2016 ... ... Luciana Lagana specializes in research on discriminated minorities’ quality of life and ... this purpose, she is creating advocacy documentaries to be tested through research to ...
(Date:5/23/2016)... , ... May 23, 2016 , ... ... on its Chesterfield, Missouri, campus, Standard Process Inc. awarded $6,000 in ... Siewert and Chloe Tillman. Each student is in her fifth trimester of classes ...
(Date:5/23/2016)... ... May 23, 2016 , ... ... to residents of Westchester County for over 24 years, recently hosted its sixth ... members joined HOW for two remembrance ceremonies, each concluding with the release of ...
Breaking Medicine News(10 mins):
(Date:5/23/2016)... Non-invasive diagnostic test realizes the ... ,Technology to be presented at Yissum’s booth, at IATI-BIOMED ... Company of the Hebrew University of Jerusalem announced ... Aurum Ventures MKI, the technology investment arm of Morris ... approach for early detection of multiple diseases by analyzing ...
(Date:5/23/2016)... JERUSALEM , May 23, 2016 ... therapies for the treatment of cancer and orphan genetic ... of up to $4.4 million from the Israel Innovation ... the Israeli Ministry of Economy and Industry. The mission ... and entrepreneurship in various industries, including science and technology, ...
(Date:5/23/2016)... , May 23, 2016   Purdue ... entered into an agreement with Egalet Corporation and ... claims. As part of the agreement the companies ... will enable all three companies to develop and ... "This agreement reflects the commitment of ...
Breaking Medicine Technology: