Navigation Links
No drop in IQ seen after bypass for child heart surgery
Date:11/10/2008

The use of cardiopulmonary bypass does not cause short-term neurological problems in children and teenagers after surgery for less complex heart defects, according to pediatric researchers. The new finding contrasts favorably with previous studies that showed adverse neurological effects after newborn surgery for more complex heart conditions.

"This is good news for school-aged children who receive surgery for these less complex heart defects," said study leader Michael D. Quartermain, M.D., a pediatric cardiologist at The Children's Hospital of Philadelphia. Quartermain presented the study group's results at the American Heart Association's Scientific Sessions today in New Orleans.

The research, conducted at the Cardiac Center of Children's Hospital, studied 41 patients, aged five to 18, who underwent heart surgery at the hospital while a heart-lung machine circulated their blood (under cardiopulmonary bypass, or CPB). All the patients had milder forms of congenital heart disease usually characterized by an abnormal heart valve or by a hole between the heart's chambers.

Such defects, while present from birth, are often not detected until a patient is school age or even older. Patients do not show obvious symptoms and are otherwise healthy, but surgical intervention is often recommended to prevent complications later in life. In contrast, more complex congenital heart defects, such as hypoplastic left heart syndrome, a severely underdeveloped ventricle, are life-threatening in infancy, and require urgent surgical repair.

Previous studies of survivors of more complex heart surgery have found neurological problems, such as impaired motor development, lower I.Q. scores and reduced language skills. As medical regimens and surgical techniques have advanced, more recent studies have found milder neurological problems or normal neurological outcomes, but long-term outcomes remain a concern. Likewise, adults with acquired heart disease have sometimes suffered adverse neurological outcomes after surgery with CPB.

In the current study, researchers compared 41 pediatric heart patients who underwent CPB to a control group receiving non-heart-related surgery without CPB. Neurological and developmental testing were performed two weeks before and six months after surgery in both groups. When controlling for the effects of hospitalization and anxiety, the researchers found no significant difference between the two groups in I.Q. scores and tests of memory, motor skills or attention. Neither of the surgical groups showed a decline in neuropsychological scores after surgery.

Regarding the implications of the study, Quartermain said, "It is often challenging for the cardiologist to determine the optimal time to refer a child without symptoms to the operating room for repair of an underlying congenital heart defect. It is now clear that the potential neurodevelopmental sequelae of cardiopulmonary bypass in this group of school-aged patients should not be a major factor in this important decision."


'/>"/>

Contact: John Ascenzi
Ascenzi@email.chop.edu
267-426-6055
Children's Hospital of Philadelphia
Source:Eurekalert

Related medicine news :

1. Hispanics less likely to have repeat revascularizations 1 year after angioplasty
2. Banned Obesity Drug Tied to Heart Risks Long After Use
3. More People Living Longer After Cancer Diagnosis
4. How women can improve their quality of life after breast cancer treatment
5. Sudden Death Risk Highest 30 Days After Heart Attack
6. Cone-beam CT: Just as useful as MDCT before and after percutaneous vertebroplasty
7. Treating Osteoporosis After Hip Fracture
8. Beware of Ten Mistakes after Social Security Denies Disability Benefits
9. Promoting the healing process after a heart attack
10. New National Patient and Surgeon Surveys Show Post-Surgical Care Critical to Optimal Weight Loss After Bariatric Surgery
11. Informed-Choice Reinforces Need to Test Supplements for Inadvertent Contamination After Recent NFL Players Positive Tests
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/29/2017)... ... ... Youth Futures International (YFI) premiered its Serve, Learn, & Empower program in 2009 ... have participated in the program every summer. The 2017 Serve, Learn, & Empower ... Visit http://www.ghana.yfiexperience.org to learn more. , “I have sent my daughter ...
(Date:3/29/2017)... ... March 29, 2017 , ... AngioGenesis ... Walgreens store in Mississippi. AngioGenesis Labs, makers of HeartBoost, BrainBest and BeautyBest, achieved ... states. Ingredients in HeartBoost, an over the counter heart healthy drink, can reduce ...
(Date:3/29/2017)... (PRWEB) , ... March 29, 2017 , ... Dr. Angela ... early orthodontic treatment and accepting new pediatric patients, with or without a referral. Dr. ... patients have a better orthodontic outcome and experience. When patients receive early treatment, they ...
(Date:3/29/2017)... ... March 29, 2017 , ... Curio Wellness , a premium ... finalization of the company’s executive management team with prominent executives from both inside and ... Wellness’ Chief Operating Officer, Ted Dumbauld , who has more than twenty years ...
(Date:3/29/2017)... ... March 29, 2017 , ... Immunotherapy has emerged as one of ... and is touted to be the next revolution in our fight against this complex ... the form of immune checkpoint inhibitors such as PD-1 and PD-L1 inhibitors. , While ...
Breaking Medicine News(10 mins):
(Date:3/29/2017)... , Mar. 29, 2017 Research and ... Systems Market 2014 - 2025" report to their offering. ... ... USD 303.7 million by 2025. Increasing geriatric population prone to ... for orthopedic navigation systems over the forecast period. Osteoarthritis and ...
(Date:3/29/2017)... March 29, 2017  The Global Health Innovative ... partnership formed to battle infectious diseases around the ... million* that could help deliver a range of ... conditions. This latest round of ... clinical trial testing a pediatric formulation of a ...
(Date:3/29/2017)... BEACH, Calif. , March 29, 2017 /PRNewswire/ ... have recognized remote monitoring devices like  Soberlink Systems ...   The consensus paper, published in early 2017, ... practical and valuable in managing patient recovery." ... in the Journal of Addiction Medicine, detail a ...
Breaking Medicine Technology: