Navigation Links
No canine rabies, no canine babies: Smaller exposure risks to both children and adults
Date:11/20/2013

(Philadelphia) Thomas Jefferson University announced today that it is a Grand Challenges Explorations winner, an initiative funded by the Bill & Melinda Gates Foundation. Milosz Faber, Ph.D., an Assistant Professor in the department of Microbiology and Immunology will pursue an innovative global health and development research project, titled "Development of a single dose contraceptive rabies vaccine."

Rabies has become a seriously neglected disease in the developing world. It causes globally an estimated 70,000 human deaths and 15 million people, of which 40 percent are children, undergo rabies post-exposure prophylaxis each year. Domestic dogs, which are found in high densities in several continents and often associated with rabies, are responsible for more than 95percent of the human rabies cases world-wide. Therefore, the most effective way to control of human rabies would be the eradication of dog rabies. However, since most of the dogs in developing countries are free-ranging, elimination of dog rabies can only be achieved through a combination of vaccination and population control programs. The aim of this project is to develop a cost-effective and safe contraceptive rabies vaccine formulation that would accomplish both objectives with a single dose.

The vaccine will be based on recently developed non-pathogenic rabies variant TriGAS which targets dendritic cells and thereby strongly induces a strong and sustained immune response not only to rabies virus but also to foreign antigen such as gonadotropin-releasing hormone (GnRH). The novel vaccine formulation resulting from the studies on this project will induce, after a single inoculation, both long-term protective immunity against rabies and infertility without causing adverse effects.

Grand Challenges Explorations (GCE) funds individuals worldwide to explore ideas that can break the mold in how persistent global health and development challenges are solved. Dr. Faber's project is one of more than 80 Grand Challenges Explorations Round 11 grants announced today by the Bill & Melinda Gates Foundation.

To receive funding, Dr. Faber and other Grand Challenges Explorations Round 11 winners demonstrated in a two-page online application a bold idea in one of five critical global heath and development topic areas that included development of the next generation condom, agriculture development, and neglected tropical diseases.


'/>"/>

Contact: Edyta Zielinska
edyta.zielinska@jefferson.edu
215-955-5291
Thomas Jefferson University
Source:Eurekalert

Related medicine news :

1. The AKC Canine Health Foundation Commits Nearly $1.5 Million to Advance the Health of Dogs
2. Spectrum Surgical Offers Canine Spring Action Mouth Gags
3. SlimDoggy Releases a No Cost iPhone App with a Dog Food Ingredient Database and Canine Calorie Calculator
4. Royal Flush Havanese's List of Common Dog Related Items That Are a Danger to Canines Everywhere
5. Putting our heads together: Canines may hold clues to human skull development
6. Vapor Steam Cleaners Help Protect Puppies Against Canine Parvovirus Disease, Announces 1-800-GO-VAPOR.com
7. Mans best friend: Common canine virus may lead to new vaccines for deadly human diseases
8. Breast-Feeding Still Less Common for Black Babies: CDC
9. More Unmarried Couples Having Babies: CDC
10. Prostate cancers are fewer, smaller on walnut-enriched diet
11. Having Both Migraines, Depression May Mean Smaller Brain
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/2/2016)... Raleigh, NC (PRWEB) , ... December 02, 2016 , ... ... the Open Enrollment Period (or Annual Election Period), is ending December 7th. Currently-enrolled Medicare ... plan (Part C) or prescription drug plan (Part D) need to make changes during ...
(Date:12/2/2016)... New York, NY (PRWEB) , ... December 02, ... ... today, featuring an inspirational interview of two ostomy patients, standing as living proof ... million people suffer from digestive diseases and issues that spike around the holidays. ...
(Date:12/2/2016)... ... December 02, 2016 , ... Mediaplanet ... in USA Today, which covers the innovative treatments, therapeutic technologies, and revolutionized nutrition ... lives. “We are prolonging life 6 years in the last 3 decades,” says ...
(Date:12/2/2016)... ... 02, 2016 , ... Universal Medical Systems, Inc. (UMS) the ... company to offer robotic imaging to veterinary medicine is sponsoring the appearance of ... the American Association of Equine Practitioners 62nd Annual Convention from December 4-6, 2016 ...
(Date:12/2/2016)... , ... December 02, 2016 , ... Yisrayl Hawkins, at ... into how this current generation fits into Bible Prophecy. Yisrayl says this generation, known ... pointing to this conclusion, showing how the details line up exactly with Bible Prophecy ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)...  PipelineRx, a leading medication management technology company ... of its SaaS-based telepharmacy platform, PowerGridRx™ , ... Midyear Clinical Meeting and Exhibition, December 5-7 in ... 300 hospital clients nationally, the Company is a ... dramatically improve pharmacy operations, enhance patient safety, and ...
(Date:12/2/2016)... 2016  Maxor National Pharmacy Services, LLC ("Maxor"), today announced ... ("PSI").  The combination of Texas -based Maxor ... PSI bring together both company,s clinical expertise and high-touch patient ... industry-leading specialty pharmacy. About Maxor ... , , ...
(Date:12/2/2016)... 2, 2016 Lianluo Smart Limited (Nasdaq: ... Company") which develops, markets and sells medical devices ... China and international markets, recently attended ... Treatment New Progress Forum, co-hosted by the Institute ... , Guangdong Provincial People,s Hospital and Cardiology ...
Breaking Medicine Technology: