Navigation Links
No association found between vitamin D concentration in blood and risk of prostate cancer
Date:5/27/2008

High vitamin D concentration in the blood is not associated with a reduced risk of prostate cancer, researchers report in an article published online May 27 in the Journal of the National Cancer Institute.

Laboratory studies suggested that high doses of vitamin D may reduce the risk of prostate cancer, but epidemiological studies that have examined the relationship have reported inconsistent results.

In a nested case-control study, Jiyoung Ahn, Ph.D., and Richard Hayes D.D.S., Ph.D., of the National Cancer Institute in Bethesda, Md., and colleagues compared the vitamin D concentrations in the blood of 749 men diagnosed with prostate cancer with that of 781 men without prostate cancer. All of the men were participants in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial and were included in the regular screening arm. Vitamin D concentration was measured in a blood sample taken when the men enrolled in the study, and all prostate cancer cases included in the current analysis were diagnosed 1 to 8 years after the blood samples were taken.

The researchers found that there was no statistically significant difference in the risk of prostate cancer with increasing vitamin D concentration. The researchers did see some evidence of an increased risk of aggressive disease associated with higher concentration of vitamin D, but the trend was not statistically significant and the association did not show a linear dose-dependence.

Results from this large prospective study of men who underwent standardized prostate cancer screening in the context of a screening trial do not support the hypothesis that higher serum vitamin D status is associated with decreased risk of prostate cancer, the authors write. The study showed no association of vitamin D with nonaggressive disease; however, it raises the possibility that higher vitamin D level may be associated with increased risks for aggressive disease, although a clear monotonic doseresponse relationship was lacking.

In an accompanying editorial, Lorelei Mucci, Sc.D., and Donna Spiegelman, Sc.D., of the Harvard School of Public Health in Boston reviewed previous studies that have looked for a possible association between vitamin D and prostate cancer risk. The evidence to date does not strongly support an association between vitamin D status in adulthood and prostate cancer risk. They note that because prostate cancer is often diagnosed at an early stage and as low-grade disease, Ahn and colleagues effort to study the vitamins association with aggressive prostate cancer, which is the most important clinically, is valuable. The editorialists comment, however, that other groups have not seen a similar association, and Ahns data should be viewed in that context.


'/>"/>

Contact: Liz Savage
jncimedia@oxfordjournals.org
301-841-1287
Journal of the National Cancer Institute
Source:Eurekalert

Related medicine news :

1. Ohio Association of Health Plans Names Pinnacle Awards to Programs That Improve Health Care for Ohioans
2. American Lung Association Launches Online Photo Campaign to Expose Big Tobacco in Communities Nationwide
3. The Anxiety Disorders Association of America and The HealthCentral Network Form Alliance to Develop New Online Resources for Anxiety Disorders
4. Analysis of Millions of U.S. Births Shows Association Between Birth Defects and Preterm Birth
5. American Heart Association Ranks Americas Most Heart Friendly Cities for Women
6. Supreme Master Ching Hai International Association Delivering US$160,000 in Aid to Earthquake Survivors in China
7. American Academy of Pediatrics/American Heart Association Clarification of Statement on Cardiovascular Evaluation and Monitoring of Children and Adolescents With Heart Disease Receiving Medications for ADHD
8. Statement from Larry Minnix, President & CEO American Association of Homes and Services for the Aging, On the Government Accountability Offices (GAO) Nursing Home Oversight Report
9. Bankers Life and Casualty Company Named Corporate Honoree at Alzheimers Association Chicago Rita Hayworth Gala
10. The American College of Cardiology, American Heart Association and the Heart Rhythm Society Release Updated Cardiac Device-Based Therapy Guidelines
11. PA Homecare Association kicks off Annual Conference: Homecare advocates speak about the importance of re-balancing the healthcare system to ensure care to the citizens of the state
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... 25, 2016 , ... Austin residents seeking Mohs surgery services, can now turn ... to Dr. Russell Peckham for medical and surgical dermatology. , Dr. Dorsey brings specialization ... selective fellowship in Mohs Micrographic Surgery completed by Dr. Dorsey was under the direction ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern Californian, Dr. Omkar Marathe ... from the David Geffen School of Medicine at UCLA. He trained in Internal Medicine ... his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had the ...
(Date:6/24/2016)... ... ... A recent article published June 14 on E Online details ... to state that individuals are now more comfortable seeking to undergo not only the ... and cheek reduction. The Los Angeles area medical group, Beverly Hills Physicians (BHP) notes ...
(Date:6/24/2016)... ... 2016 , ... The Pulmonary Hypertension Association (PHA) learned during ... two significant new grants to support its work to advance research and patient ... recognizing patients, medical professionals and scientists for their work in fighting pulmonary hypertension ...
(Date:6/24/2016)... NY (PRWEB) , ... June 24, 2016 , ... Topical BioMedics, Inc, makers of Topricin ... companies that call for a minimum wage raise to $12 an hour by 2020 and ... This will restore the lost value of the minimum wage, assure the wage floor does ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... , June 27, 2016  VMS Rehab Systems, Inc. ... will take whatever measures required to build a strong ... which is currently listed on the OTC Markets-pink current ... Chairman and CEO, "We are seeing an anomaly in ... understand, not only by the Company, but shareholders and ...
(Date:6/24/2016)... , June 24, 2016   Bay ... Rehabilitation Network,s Dean Center for Tick Borne ... Medicine and Rehabilitation, MIT Hacking Medicine, University of ... Innovation, today announced the five finalists of ... Lyme disease.  More than 100 scientists, clinicians, researchers, ...
(Date:6/24/2016)... CLEMENTE, Calif. , June 24, 2016  American Respiratory Labs ... company, is now able to perform sophisticated lung assessments in patients, ... Technologies , Inc. Patients are no longer limited ... ndd,s EasyOne PRO ® , ARL patients like Jeanne R. of ... done in the comfort of her own home. ...
Breaking Medicine Technology: