Navigation Links
No Verdict Yet on Grape Seed Extract vs. Breast Cancer

Researchers plan more controlled study at different dosages

THURSDAY, April 23 (HealthDay News) -- More research is needed to determine whether grape seed extract lowers hormone levels in postmenopausal women and provides protection against breast cancer, say researchers at the City of Hope cancer center in Duarte, Calif.

Because studies have suggested that grape seed extract inhibits aromatase, an enzyme that helps in estrogen production, the researchers looked at whether grape seed extract supplements could lower hormone levels in postmenopausal women.

What they found was a dramatic and sustained decrease in one patient with high baseline estrogen levels. But variable baseline hormone levels in the participants prevented them from reaching firm conclusions, they said.

Their findings were presented at the annual meeting of the American Association for Cancer Research, in Denver.

"We found that there are many variables that affect a woman's hormone level, including diet, concurrent medications and other supplements," the study's leader, Dr. Melanie Palomares, an assistant professor of cancer screening and prevention, said in a City of Hope news release.

"It was difficult to ascribe changes observed so far directly to the grape seed extract supplements, though three of the seven participants treated on the highest dose level had results showing promise," she said. "Our pharmacokinetic observations in this trial merit further investigations to evaluate the prevention benefits of grape seed extract."

Palomares is continuing the research with higher doses of grape seed extract in more carefully selected women. Once the most appropriate dose is determined, she plans to conduct a follow-up clinical trial to measure how grape seed extract affects breast tissue risk biomarkers.

More information

The U.S. National Cancer Institute has more about breast cancer prevention.

-- Robert Preidt

SOURCE: City of Hope, news release, April 21, 2009

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. AAID Hails Florida Court Verdict Allowing Advertising of Bona Fide Dental Credentials
2. Chicago Lawyers Represents Plaintiff in Trial That Results in $23.7 Million Jury Verdict over Fatal 2004 Trucking Accident
3. $12 Million New Jersey Medical Malpractice Verdict for Wrongful Death of a 21-Year-Old Man After Having Wisdom Teeth Removed
4. Subway Accident Victim Wins $3.595 Million Verdict Against The New York City Transit Authority
5. Steve Teal, Santa Rosa Attorney, Obtains $850,000 for Client in Highest Hospital Negligence Verdict in Mendocino County
6. New York Attorney Obtains $2.25 Million Verdict for Client Injured on Grounds of Bronx Eye Surgery Clinic
7. Texas Jury Awards $250 Million Patent Infringement Verdict Against Boston Scientific in Balloon Catheter Lawsuit
8. Asbestos Verdict Upheld by Louisiana Court of Appeal, Announces Baron & Budd
9. Seattle-Based Law Firm Williams Kastner Receives Significant Defense Verdict in Trade Secret Business Litigation Case
10. Grassini & Wrinkle Law Firm Are Awarded Largest PI Verdict in Ventura County History
11. $30.3 Million Jury Verdict Believed to Be New Jerseys Largest
Post Your Comments:
Related Image:
No Verdict Yet on Grape Seed Extract vs. Breast Cancer
(Date:6/27/2016)... (PRWEB) , ... June 27, 2016 , ... ... for mental health professionals, announced today its affiliation with Tennessee Counseling Association. ... solutions to the network of the Tennessee Counseling Association, adding exclusive benefits and ...
(Date:6/26/2016)... ... ... Quality metrics are proliferating in cancer care, and are derived from many of ... beholder, according to experts who offered insights and commentary in the current issue of ... full issue, click here . , For the American Society of Clinical Oncology ...
(Date:6/26/2016)... ... 26, 2016 , ... Brent Kasmer, a legally blind and certified personal trainer is helping to ... app. The fitness app plans to fix the two major problems leading the fitness industry ... fits all type program , They don’t eliminate all the reasons people quit ...
(Date:6/25/2016)... ... ... The temporary closing of Bruton Memorial Library on June 21 due to a possible lice ... overlooked aspect of head lice: the parasite’s ability to live away from a human host, ... a necessary one in the event that lice have simply gotten out of control. , ...
(Date:6/25/2016)... ... June 25, 2016 , ... Dr. ... from injury. Recently, he has implemented orthobiologic procedures as a method for treating ... one of the first doctors to perform the treatment. Orthobiologics are substances that ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016 ... Market by Type (Standard Pen Needles, Safety Pen Needles), ... (Insulin, GLP-1, Growth Hormone), Mode of Purchase (Retail, Non-Retail) ... MarketsandMarkets, This report studies the market for the forecast ... to reach USD 2.81 Billion by 2021 from USD ...
(Date:6/23/2016)... 23, 2016  MedSource announced today that it ... software solution of choice.  This latest decision demonstrates ... to their clients by offering a state-of-the-art electronic ... establishes nowEDC as the EDC platform of choice ... clients.  "nowEDC has long been a preferred EDC ...
(Date:6/23/2016)... Ill. , June 23, 2016  In a startling report ... are failing their residents by lacking a comprehensive, proven plan to ... a definitive ranking of how states are tackling the worst ... to only four states – Kentucky , ... Vermont . Of the 28 failing states, three ...
Breaking Medicine Technology: