Navigation Links
No Verdict Yet on Grape Seed Extract vs. Breast Cancer

Researchers plan more controlled study at different dosages

THURSDAY, April 23 (HealthDay News) -- More research is needed to determine whether grape seed extract lowers hormone levels in postmenopausal women and provides protection against breast cancer, say researchers at the City of Hope cancer center in Duarte, Calif.

Because studies have suggested that grape seed extract inhibits aromatase, an enzyme that helps in estrogen production, the researchers looked at whether grape seed extract supplements could lower hormone levels in postmenopausal women.

What they found was a dramatic and sustained decrease in one patient with high baseline estrogen levels. But variable baseline hormone levels in the participants prevented them from reaching firm conclusions, they said.

Their findings were presented at the annual meeting of the American Association for Cancer Research, in Denver.

"We found that there are many variables that affect a woman's hormone level, including diet, concurrent medications and other supplements," the study's leader, Dr. Melanie Palomares, an assistant professor of cancer screening and prevention, said in a City of Hope news release.

"It was difficult to ascribe changes observed so far directly to the grape seed extract supplements, though three of the seven participants treated on the highest dose level had results showing promise," she said. "Our pharmacokinetic observations in this trial merit further investigations to evaluate the prevention benefits of grape seed extract."

Palomares is continuing the research with higher doses of grape seed extract in more carefully selected women. Once the most appropriate dose is determined, she plans to conduct a follow-up clinical trial to measure how grape seed extract affects breast tissue risk biomarkers.

More information

The U.S. National Cancer Institute has more about breast cancer prevention.

-- Robert Preidt

SOURCE: City of Hope, news release, April 21, 2009

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. AAID Hails Florida Court Verdict Allowing Advertising of Bona Fide Dental Credentials
2. Chicago Lawyers Represents Plaintiff in Trial That Results in $23.7 Million Jury Verdict over Fatal 2004 Trucking Accident
3. $12 Million New Jersey Medical Malpractice Verdict for Wrongful Death of a 21-Year-Old Man After Having Wisdom Teeth Removed
4. Subway Accident Victim Wins $3.595 Million Verdict Against The New York City Transit Authority
5. Steve Teal, Santa Rosa Attorney, Obtains $850,000 for Client in Highest Hospital Negligence Verdict in Mendocino County
6. New York Attorney Obtains $2.25 Million Verdict for Client Injured on Grounds of Bronx Eye Surgery Clinic
7. Texas Jury Awards $250 Million Patent Infringement Verdict Against Boston Scientific in Balloon Catheter Lawsuit
8. Asbestos Verdict Upheld by Louisiana Court of Appeal, Announces Baron & Budd
9. Seattle-Based Law Firm Williams Kastner Receives Significant Defense Verdict in Trade Secret Business Litigation Case
10. Grassini & Wrinkle Law Firm Are Awarded Largest PI Verdict in Ventura County History
11. $30.3 Million Jury Verdict Believed to Be New Jerseys Largest
Post Your Comments:
Related Image:
No Verdict Yet on Grape Seed Extract vs. Breast Cancer
(Date:10/13/2017)... Little Rock, AR (PRWEB) , ... October 13, ... ... owned firm with locations throughout Arkansas that offers insurance and financial preparation services, ... to benefit the Rock City Rescue organization. , Rock City Rescue is a ...
(Date:10/13/2017)... PITTSBURGH, Pa. (PRWEB) , ... October 13, 2017 , ... ... the dark poses a problem. Fortunately, an inventor from Austin, Texas, has identified a ... access to medication in darkness or restricted lighting. As such, it eliminates the need ...
(Date:10/13/2017)... ... October 13, 2017 , ... The International Association of Eating ... excellence for the field of eating disorders, announces the opening of early registration ... Orlando, Florida at the Omni Resort at ChampionsGate. , The annual ...
(Date:10/13/2017)... ... October 13, 2017 , ... Southern ... and Jennifer Huggins, PharmD ’17, along with clinical associate professor Janice Frueh, ... cardiovascular diseases during the 15th Annual Women’s Health Conference. The SIU School ...
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... Apple ... care services, staged a mock evacuation of the facility as part of a disaster ... Fire Department, Echo Hose EMS and Shelton City Emergency Manager, as well as the ...
Breaking Medicine News(10 mins):
(Date:9/18/2017)... 2017 EpiVax, Inc. ("EpiVax") a ... immune engineering, today announced a new NIH-funded ... ... and presents a challenge for traditional flu ... be effective. Using state-of-the-art bioinformatics and molecular modeling methods, ...
(Date:9/12/2017)... , Sept. 12, 2017   EcoVadis , the leading platform ... published the first annual edition of its Global CSR Risk and Performance ... evaluated by EcoVadis, based on Scorecard Ratings that analyzed nearly 800,000 data ... ... ...
(Date:9/12/2017)... Sept. 12, 2017  ValGenesis Inc., the global ... is pleased to announce the appointment of Dr. ... its Board of Directors and Chairman of Advisory ... life science companies to manage their entire validation ... paper in this process. Furthermore, ValGenesis VLMS enables ...
Breaking Medicine Technology: