Navigation Links
No ESKAPE! New drugs against MRSA, other superbugs still lacking
Date:12/1/2008

bad bugs."

The ESKAPE Bacteria

According to the latest data from the Centers for Disease Control and Prevention (CDC), the six ESKAPE bacteria are responsible for two thirds of all health care-associated infections (HAIs). They are:

Enterococcus species: Enterococci were responsible for one out of eight HAIs in 2006-2007. A 2004 study found about two thirds of E. faecium bloodstream infections were resistant to vancomycin, one of the most commonly used antibiotics to treat enterococcal infections. Some physicians are treating vancomycin-resistant E. faecium with the new antibiotics linezolid, daptomycin, and tigecycline, but these drugs have not been studied extensively for use against these infections. Furthermore, many patients cannot tolerate them.

Staphylococcus aureus: The only household name among the ESKAPE bugs, methicillin-resistant Staphylococcus aureus (MRSA) outbreaks have been reported among otherwise-healthy athletes, military recruits, school children, and others. MRSA caused an estimated 94,000 invasive infectionsmore than 19,000 of them fatalin 2005, according to a recent study by CDC. MRSA is a serious and growing threat in hospitals and other health care facilities, but this study found 14 percent of patients had no obvious exposure to a health care facility.

MRSA has drawn more attention from the pharmaceutical industry than any of the other ESKAPE bugs. Several new drugs are effective against these infections. However, all but one are given intravenously and are primarily to be used in hospitals. Many patients cannot tolerate these potent drugs. Also, only one drug in the pipeline works using a mechanism different from the ones to which some bad bugs have already developed resistance.

Klebsiella species: These gram-negative bacteria cause infections in the urinary, biliary, and gastrointestinal tracts, and in trauma wounds. Klebsiella species and their
'/>"/>

Contact: Steve Baragona
sbaragona@idsociety.org
703-299-0412
Infectious Diseases Society of America
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. New review suggests caution on drugs to raise good cholesterol
2. Can cancer drugs combine forces?
3. Study provides hope that some transplant patients could live free of antirejection drugs
4. Study provides hope that some transplant patients could live free of anti-rejection drugs
5. RA Drugs Linked to Slight Skin Cancer Risk
6. Report on patients access to cancer drugs uses flawed methods to reached flawed conclusions
7. Rock N Roll: Sex, Drugs and an Early Exit
8. Australian-led international study shows blood pressure drugs cut death rate in type 2 diabetes
9. Consumer Reports Analysis: Drugs for Nerve Pain, Fibromyalgia Effective, But Not Always Best
10. Are Bargaining Groups Hired by Independent Drugstores Causing Payment Delays to Pharmacies?
11. 2 drugs equally effective for heart patients undergoing angioplasty, Mayo study finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/12/2014)... CA (PRWEB) July 12, 2014 For those ... are bodies can readily absorb the nutrients in food. The ... particles that are small enough to be absorbed by human ... team, a lack of enzymes in regular food is the ... a product that was started by Michelle DelPresto, a mother ...
(Date:7/12/2014)... “Critical Care Therapeutics in Major Developed ... PCCs and Recombinant Products to Drive Market,” which ... in the US, UK, France, Germany, Italy, Spain, ... of market size for 2013, along with market ... that are being treated using the five major ...
(Date:7/12/2014)... As reported in this July 1st ... Technology), the June 25th, 2014 Supreme Court ruling in Riley ... It was also met with both cheers and jeers ... was seen from an individual privacy perspective, or a law ... is now precedent which will require law enforcement officials to ...
(Date:7/12/2014)... July 12, 2014 Dubai is buzzing ... legend is heading to the UAE. The National ... will be in the UAE from 28-31 October to ... support of diabetes awareness. The event is being organized ... and event management company based in Dubai. The announcement ...
(Date:7/12/2014)... Texas (PRWEB) July 12, 2014 ... Breastfeeding Made Simple as a valuable new resource for ... roughly two-thirds of American women work away from their ... sources touting the benefits of breastfeeding, but often feel ... to nurse their babies. With its evidence-based insights, and ...
Breaking Medicine News(10 mins):Health News:New Super Digestive Enzyme, DZ10, Supercharges The Digestion Process 2Health News:Critical Care Therapeutics in Major Developed Market is Expected to Grow at a CAGR of 4.7% to $2.5 Billion in 2019 2Health News:Critical Care Therapeutics in Major Developed Market is Expected to Grow at a CAGR of 4.7% to $2.5 Billion in 2019 3Health News:Critical Care Therapeutics in Major Developed Market is Expected to Grow at a CAGR of 4.7% to $2.5 Billion in 2019 4Health News:Critical Care Therapeutics in Major Developed Market is Expected to Grow at a CAGR of 4.7% to $2.5 Billion in 2019 5Health News:Critical Care Therapeutics in Major Developed Market is Expected to Grow at a CAGR of 4.7% to $2.5 Billion in 2019 6Health News:Mobile Device Forensics Guidelines Play Key Role in Supreme Court’s Smartphone Evidence Warrant Decision 2Health News:Mobile Device Forensics Guidelines Play Key Role in Supreme Court’s Smartphone Evidence Warrant Decision 3Health News:Mobile Device Forensics Guidelines Play Key Role in Supreme Court’s Smartphone Evidence Warrant Decision 4Health News:Mobile Device Forensics Guidelines Play Key Role in Supreme Court’s Smartphone Evidence Warrant Decision 5Health News:Los Angeles Basketball Legend Headed to Dubai 2Health News:Los Angeles Basketball Legend Headed to Dubai 3Health News:Praeclarus Press Announces the Release of Working and Breastfeeding Made Simple by Nancy Mohrbacher, A Much Needed Resource For Today's Working Mothers 2
... for the Cure,s Global Promise, DALLAS, Oct. ... the,leader of the global breast cancer movement, is ... Hewko as vice president of,international, reporting to Komen ... (Logo: http://www.newscom.com/cgi-bin/prnh/20070122/NYM084LOGO ), Hewko will guide ...
... Members who choose Regence,s,Health Savings Account (HSA) will ... company has added U.S. Bank as a banking partner. ... care banking,and its strong consumer track record., "We ... and,brand like U.S. Bank to offer our members the ...
... Barnett, London, Ontario, receives the Karolinska Stroke Award for ... SEK. The laureate will receive the prize from the ... Stroke Update meeting in Stockholm November 17, 2008. ... award. The Karolinska Institutet also awards the Nobel ...
... ANGELES, Oct. 29 George Abercrombie, president ... address Los Angeles,business leaders at the National ... He plans to tell them,that the threat ... challenges,unlike those anticipated with traditional emergency preparedness ...
... Cojocaru forms Team Cojo to fight PKD, ... own life-saving,kidney transplant, fashion critic and Entertainment Tonight ... the 12.5 million people,worldwide affected by Polycystic Kidney ... world,s most common, life-threatening genetic,diseases, affecting more people ...
... Health Literacy Month, recognized in October, promotes ... information. According to the National Assessment of Adult ... health literacy - skills needed to manage their ... the focus of an ongoing study at the ...
Cached Medicine News:Health News:Susan G. Komen for the Cure(R) Strengthens Global Mission With Addition of Vice President, International 2Health News:Susan G. Komen for the Cure(R) Strengthens Global Mission With Addition of Vice President, International 3Health News:Regence Teams With U.S. Bank to Offer New Health Savings Account Solution 2Health News:Dr. Henry Barnett becomes first person outside Europe to receive Karolinska Stroke Award 2Health News:CEO to Address Los Angeles Business Leaders About Developing Pandemic and Business Continuity Plans 2Health News:CEO to Address Los Angeles Business Leaders About Developing Pandemic and Business Continuity Plans 3Health News:Cojo to Hit the Streets of LA for 2008 Walk for PKD 2Health News:$8.6 million grant to MU will fund efforts to improve health literacy, health outcomes 2
(Date:7/10/2014)... 10, 2014  RESMED INC. (NYSE: RMD ) ... fiscal year ended June 30, 2014 results on Thursday, July ... A press release with ResMed,s results will be issued after ... a webcast to discuss operating results and future outlook. ... p.m. US Pacific Time and the live webcast of the ...
(Date:7/10/2014)... , July 10, 2014  Decision Resources ... surveyed infectious disease (ID) specialists are willing to ... Orbactiv (oritavancin) for use as OPAT, approximately two-thirds ... these agents to their hospital inpatients. However, our ... OPAT patients are initiated on OPAT following hospital ...
(Date:1/15/2014)... 2014 /PRNewswire-iReach/ -- ChinaMarketResearchReports.com adds "China Orthopedic Instrument Industry ... (Photo: http://photos.prnewswire.com/prnh/20140115/MN46792 ) Benefiting ... China,s orthopedic instrument industry has ... size rising from 3.28 billion yuan in 2006 to ...
Breaking Medicine Technology:ResMed To Announce Fourth Quarter And Fiscal Year-End 2014 Results 2Long-Acting Antibiotics Offering Once-Weekly Dosing Will See Favorable Uptake and Use as Outpatient Parenteral Antimicrobial Therapy (OPAT) 2Long-Acting Antibiotics Offering Once-Weekly Dosing Will See Favorable Uptake and Use as Outpatient Parenteral Antimicrobial Therapy (OPAT) 3Orthopedic Instrument Industry in China Markets Forecast to 2015 2Orthopedic Instrument Industry in China Markets Forecast to 2015 3
... 29, 2012 Keryx Biopharmaceuticals, Inc. (NASDAQ: ... development and commercialization of medically important pharmaceutical products for ... disease (the "Company"), today announced its results for the ... At December 31, 2011, the Company had cash, ...
... Feb. 29, 2012  Amgen (NASDAQ: AMGN ) ... Annual Healthcare Conference on Monday, March 5, 2012 at ... approximately 2:50 p.m. Eastern Standard Time.  Jonathan M. Peacock, ... will present. Live audio of the presentation can be ...
Cached Medicine Technology:Keryx Biopharmaceuticals, Inc. Announces Fourth Quarter and Year-End 2011 Financial Results 2Keryx Biopharmaceuticals, Inc. Announces Fourth Quarter and Year-End 2011 Financial Results 3Keryx Biopharmaceuticals, Inc. Announces Fourth Quarter and Year-End 2011 Financial Results 4Keryx Biopharmaceuticals, Inc. Announces Fourth Quarter and Year-End 2011 Financial Results 5
... fixed pipette is ideal for ... volume. Fixed volume FInnpipettes offer ... as other Finnpipette Digital pipettes: ... blow-out (1-40ul), Soft-touch tip ejection, ...
... precision, ergonomics, and value!, Comfortable ... soft non-slip, contoured handle , Finer ... plunger spring action , Completely autoclavable ... the need for recalibration , Easy-to-read ...
Inquire...
Inquire...
Medicine Products: