Navigation Links
Nicotine May Help Prevent Damage from Bioterrosim Toxin and Growth Factors in Heart Disease News from Molecular Medicine
Date:5/6/2009

Nicotine has potent anti-inflammatory properties and British scientists have now found that it is helpful in delaying the effects of ricin, the toxic substance feared in biologic warfare.

Manhasset, NY (Vocus) May 6, 2009 -- Nicotine has potent anti-inflammatory properties and British scientists have now found that it is helpful in delaying the effects of ricin, the toxic substance feared in biologic warfare. Jon G. Mabley and his colleagues at the University of Brighton found that nicotine works through the cholinergic inflammatory pathway to block the anti-inflammatory and tissue-destroying effects of ricin, a compound derived from castor beans. The study was conducted in laboratory models but the scientists believe that nicotine agonists could potentially be used in patients exposed to ricin as a stopgap measure before other treatments can take effect.

The British investigators studied the effect of nicotine on animals exposed to ricin and found it reduced death and organ failure. "The protective effect of nicotine appears to be associated with its anti-inflammatory effect, suggesting a possible therapeutic strategy of activating the cholinergic anti-inflammatory pathway following ricin exposure to protect against multiple organ failure. The overall effect of nicotine on maintaining liver and kidney function while reducing systemic inflammation may account for the reduced mortality observed with ricin exposure," the authors wrote.

Activation of the anti-inflammatory cholinergic pathway is now undergoing testing to reduce inflammation in a wide range of diseases.

In another study that appears in the May-June 2009 issue of Molecular Medicine, a team of scientists from Argentina report identifying genomic instability in the mitochondria of cells culled from breast cancer tissue. The scientists analyzed two markers along the mitochondrial DNA and found 38 of the 94 tissue samples showed some genetic instability, suggesting that this could be the mechanism that allows cancer cells to take hold.

You can view all of the articles in the May-June issue by visiting the journal's Web site at www.molmed.org.

Molecular Medicine is a bimonthly journal published by The Feinstein Institute for Molecular Research. The peer-reviewed journal strives to understand normal body functioning and disease pathogenesis at the molecular level, which may allow researchers and physician-scientists to use that knowledge in the design of specific molecular tools for disease diagnosis, treatment, prognosis, and prevention. The journal, a bimonthly publication, serves as a forum through which scientists and researchers can communicate recent discoveries to a multi-disciplinary, international audience interested in understanding and curing disease.

To listen to the latest podcast on these studies visit www.molmed.org/podcast.html (episode 46).

###

Read the full story at http://www.prweb.com/releases/2009/05/prweb2395344.htm.


'/>"/>
Source: PRWeb
Copyright©2009 Vocus, Inc.
All rights reserved  

Related medicine news :

1. Nicotine Replacement May Help Smokers Quit Gradually
2. Pennsylvania to Offer Free Nicotine Replacement Therapy Kits Beginning Feb. 2
3. Nicotine gum effective for gradual smoking reduction and cessation
4. Watson Pharmaceuticals Receives FDA Approval for Mint Coated Nicotine Gum
5. FTC Acts to Prevent Tobacco Industry Deception About Tar, Nicotine Levels; Congress Should Give FDA Authority Over Tobacco Products
6. Todays Smokers More Addicted to Nicotine
7. US Nicotine Addiction Reaches 15-Year High
8. American Legacy Foundation(R) Statement of Support for the Federal Trade Commission Reversal on Tar and Nicotine Yield Statements on Cigarettes
9. FTC Acts to Prevent Tobacco Industry Deception About Tar, Nicotine Levels; Congress Should Go Further by Giving FDA Authority Over Tobacco Products
10. Potential dangers faced by narcoleptics who use nicotine outlined in new abstract
11. Video: GlaxoSmithKline Consumer Healthcare Offers Free Nicotine Lozenges for All Certified Pilots and Air Traffic Controllers to Help Them Safely Quit Smoking
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Nicotine May Help Prevent Damage from Bioterrosim Toxin and Growth Factors in Heart Disease News from Molecular Medicine
(Date:10/13/2017)... ... October 13, 2017 , ... While it’s often important to take certain medications ... from Austin, Texas, has identified a solution. , She developed a prototype for MOTION ... As such, it eliminates the need to turn on a light when taking medication ...
(Date:10/13/2017)... ... , ... PurhealthRX , a leading Health and Nutrition Company, is announcing ... full spectrum CBD oil will revolutionize the rapidly growing CBD market by reducing the ... incorporated into liquid products, while reducing costs to end users. , The team of ...
(Date:10/13/2017)... ... ... Apple Rehab Shelton Lakes , which specializes in the delivery of ... part of a disaster drill on October 3rd. , Apple Rehab participated with the ... as well as the Connecticut Long Term Care Mutual Aid Plan (LTC-MAP). The ...
(Date:10/13/2017)... ... , ... Ellevate Network, the leading network for professional women, brought together some ... at their inaugural Summit in New York City in June. The event was livestreamed ... over 3 million. To watch the Mobilize Women video, click here . ...
(Date:10/13/2017)... ... October 13, 2017 , ... Talented host, actor Rob ... sciatica in a new episode of "Success Files," which is an award-winning educational ... and investigates each subject in-depth with passion and integrity. , Sciatica occurs when ...
Breaking Medicine News(10 mins):
(Date:10/7/2017)... Texas , Oct. 6, 2017   Provista, ... with more than $100 billion in purchasing power, today ... news and information. The Newsroom is the ... and industry trends, infographics, expert bios, news releases, slideshows ... having access to a wealth of resources at their ...
(Date:10/4/2017)... the Centers for Disease Control and Prevention (CDC), influenza vaccination should ... helping communities across Massachusetts , Connecticut ... shots through the end of the month. *Some exclusions apply ... ... is by the end of October, according to the Centers for Disease ...
(Date:10/2/2017)... Oct. 2, 2017  Eli Lilly and Company (NYSE: ... for the third quarter of 2017 on Tuesday, October ... on that day with the investment community and media ... The conference call will begin at 9 a.m. Eastern ... a live webcast of the conference call through a ...
Breaking Medicine Technology: