Navigation Links
Next decade offers promise for treatment of spinal cord injuries

Although new developments in the management of spinal cord injuries (SCI) are on the horizon, any eventual cure for the condition is more likely to involve a multidisciplinary approach, drawing from expertise in several fields, according to a review article published in the April 2010 issue of the Journal of the American Academy of Orthopaedic Surgeons (JAAOS).

  • Each year, approximately 12,000 men and women sustain and survive spinal cord injuries, and about 259,000 Americans currently live with a long-lasting SCI.
  • Although traditionally associated primarily with young adults, today the average age of SCI patients has risen to 40.2 years.
  • Automobile crashes are the most common cause of SCI, and males are most often affected, comprising almost 81 percent of all SCI patients.

According to Ranjan Gupta, MD, chair of the department of orthopaedic surgery and professor of orthopaedic surgery, anatomy and neurobiology, and biomedical engineering at the University of California, Irvine, newer therapeutic approaches including stem cell therapy and novel drug formulations, hold special promise for management of SCI patients.

"Yet, spinal cord injuries are especially difficult to treat because they involve more than a direct injury to the spine," noted Dr. Gupta. "The primary mode of an SCI involves changes to the patient's anatomy that occur as the result of the actual traumatic event. Secondary injuries may occur as a result of how the body responds to the primary injury, usually by producing scar tissue that can make treatment problematic."

Dr. Gupta added that it is in the area of these secondary injuries that there are many promising areas of research, from optimizing the acute management of the patient to pharmacologic interventions to cellular transplantation.

"Yet, to maximize the chances for recovery after SCI, early surgical intervention is essential," he stated.

With the sustained, robust attention from scientists and clinicians, as well as the continued active support from the National Institutes of Health, there should be substantial changes in the clinical management of SCI over the next decade. "As long as the field is being actively researched, there is cause for renewed and continued hope," Dr. Gupta continued.

"Patients with spinal cord injuries face possible significant neurologic problems, resulting in paralysis and other disabilities. Innovative treatment strategies such as stem cell transplantation have enjoyed renewed interest under the current administration," Dr. Gupta noted.

"Currently, the FDA has been more receptive to cellular transplantation trials, with one of the first trials being actively planned in the next two years," he said. "While there have been several animal studies showing benefits from various pharmacological interventions, the human clinical trials are still pending."

Dr. Gupta noted ongoing clinical trials -- including the Surgical Treatment of Acute Spinal Cord Injury Study (STASCIS) -- continue to explore new approaches to the management of SCI, including multidiscplinary approaches that rely on several specialties to shape a successful treatment.

"It is extremely unlikely that SCI will respond to one single intervention, or that there will be a 'magic bullet,' " he concluded. "Rather, the treatment of SCI will undoubtedly require a multidisciplinary approach and management."


Contact: Lauren Pearson
American Academy of Orthopaedic Surgeons

Related medicine news :

1. Scientific community to set research agenda for infection prevention and control for next decade
2. Health Groups Ask Supreme Court to Authorize Financial Penalties on Tobacco Companies for Decades of Wrongdoing
3. Dcor Grille Leads into the Next Decade with its New Security Web Site
4. Decade of Decline in U.S. Teen Pregnancies Ends
5. Pelosi Statement on New Report That Health Reform Will Create 4 Million More Jobs Over the Next Decade
6. Biggest Medical Breakthroughs and Milestones of the Last Decade Broadcast on SIRIUS XMs Doctor Radio Channel
7. Narconon Salutes Its 1,200 Staff Worldwide on 13,000 Lives Saved This Last Decade
8. Breast-Feeding Can Help Moms Heart Decades Later
9. Breast Cancer Survivor Tackles the Missing Link: Inspiring Event Offers Women Real Life Advice to Thrive After Medical Treatment Ends
10. A.C. Moore Arts & Crafts, Inc. Offers Creative Way to Help Easter Seals and Families Living with Autism
11. President of Shimmering Resumes Offers Professional Resume To Bush Speechwriter, David Frum
Post Your Comments:
(Date:11/24/2015)... York, N.Y. (PRWEB) , ... November 24, 2015 , ... ... Giving Tuesday, the global movement driven by social media and the generosity of people ... Speaks, then encourage their social media networks to give – and share the personal ...
(Date:11/24/2015)... Tennessee (PRWEB) , ... November 24, 2015 , ... ... Pharmacy Quality Trend Report . Throughout the past year there have been multiple breakthroughs ... mature state. During this transition, PharmMD has enabled their customers and partners to stay ...
(Date:11/24/2015)... San Mateo, CA (PRWEB) , ... November 24, 2015 , ... “I am so thrilled, ... teacher Stephanie Lederman after learning she had won a $7,500 School Lounge Makeover® from ... Chandler, Arizona, where most of the staff has a much longer tenure. , “This is ...
(Date:11/24/2015)... ... November 24, 2015 , ... Add a fresh touch ... an easy and affordable way to bring long-lasting style and cheer to any space. ... oxygen, clean the air and keep on giving all year long. , “Holiday plants ...
(Date:11/24/2015)... ... ... Tudore Tranquility is a new restaurant in Tokyo, Japan that recently opened their ... is full of flavorful and creative dishes that exceed expectations. It is an elegant ... intimate event. The décor looks stunning with gold and beige tones. , Tudore ...
Breaking Medicine News(10 mins):
(Date:11/24/2015)... F1000Workspace - a research collaboration, reference management and ... six months ago. --> F1000Workspace - a ... since it was launched just six months ago. --> ... F1000Workspace - a research collaboration, reference management and authoring ... months ago. --> --> ...
(Date:11/24/2015)... , Nov. 24, 2015  Family Rentals, ... recently announced the launch of their newly designed, ... --> --> ... --> --> Now, renting ... travel and vacation, just got a whole lot ...
(Date:11/24/2015)... Pa. , Nov. 24, 2015  NuShield, Inc., an industry leader in LCD screen protection ... and stationary computer technology as part of their patient monitoring or electronic documentation system. ... ... ... A ...
Breaking Medicine Technology: