Navigation Links
Nexavar in Combination with Chemotherapy Shown to Extend Progression-Free Survival in Patients with Advanced Breast Cancer
Date:7/22/2009

WAYNE, N.J. and EMERYVILLE, Calif., July 22 /PRNewswire-FirstCall/ -- Bayer HealthCare Pharmaceuticals and Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX) today announced that their first cooperative group-sponsored randomized Phase 2 trial in advanced metastatic breast cancer met its primary endpoint of progression-free survival. The study evaluated Nexavar(R) (sorafenib) tablets in combination with the oral chemotherapeutic, capecitabine, in patients with locally advanced or metastatic HER-2 negative breast cancer. Study findings demonstrated that the median progression-free survival was extended in patients treated with Nexavar and capecitabine compared to patients receiving capecitabine and placebo. These results were statistically significant (p = .0006). In this trial, the safety and tolerability of the combination was as expected and did not show any new or unexpected toxicities. A complete data analysis from this study is expected to be presented at an upcoming scientific meeting.

"Based on these encouraging data, Onyx and Bayer are evaluating various strategies for Nexavar in breast cancer. Nexavar is already benefiting patients worldwide with liver cancer and kidney cancer," said Todd Yancey, M.D., vice president of clinical development at Onyx. "Despite significant treatment advances, breast cancer continues to be the leading cause of cancer death in women.(i) We hope to establish Nexavar as an important new treatment option for patients with this devastating disease."

"This outcome represents a positive signal of the potential benefit of this combination for patients with advanced breast cancer and is the first statistical demonstration of efficacy for a multi-tyrosine kinase inhibitor in this disease," said Jose Baselga, M.D., chairman and professor of medicine at Vall d
'/>"/>

SOURCE Onyx Pharmaceuticals, Inc.; Bayer HealthCare Pharmaceuticals Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine news :

1. Onyx Pharmaceuticals Announces a Teleconference and Webcast to Provide an Update on Nexavar; Previously Announced Fourth Quarter and Full Year 2007 Financial Results Teleconference Rescheduled
2. New Analyses Confirm Nexavars Efficacy and Safety in Multiple Patient Subsets With Liver Cancer
3. Nexavar Approved in Japan for the Treatment of Advanced Liver Cancer
4. Phase 3 Trial Initiated to Evaluate Combination Therapy of Nexavar(R) and Tarceva(R) in Patients with Liver Cancer
5. Bayer and Onyx Initiate Phase 3 Trial of Nexavar in Non-Small Cell Lung Cancer
6. Promising drug combination may help those with ocular melanoma that has spread
7. Combination therapy reverses effects of portal hypertension in rats
8. Combination vaccines okay for infants, study shows
9. Antidepressants and painkillers - a dangerous combination
10. Intra-arterial combination chemotherapy induces long-term survival for hepatocellular carcinoma
11. U.S. Oncology Initiates Complete Phase Ib Trial of Brostallicin Combination Therapy in Advanced Solid Tumors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/23/2014)... July 23, 2014 Rich Dad® Education, a ... of their charity yard sale to support Habit for Humanity ... 100% of the proceeds will be donated to Habitat for ... are being donated to the Habitat for Humanity ReStore thrift ... 33903. , One of the highlights of the yard ...
(Date:7/23/2014)... The American Telemedicine Association (ATA) is ... meeting and tradeshow focused exclusively on telemedicine, telehealth ... 5,000 attendees and more than 250 cutting-edge healthcare ... in Los Angeles. , ATA’s annual meeting attracts ... researchers, clinicians, hospital and university administrators, program managers ...
(Date:7/23/2014)... 2014 Global Cardio Care, Inc., a ... Counterpulsation (EECP), is celebrating the 100th birthday of ... the health center. , Weber has been plagued ... ongoing EECP therapy since 1999, he no longer suffers ... of Global Cardio Care, introduced the Sara Soulati ...
(Date:7/23/2014)... Thousands of DePuy Pinnacle hip lawsuits ... federal multidistrict litigation underway in U.S. District Court, Northern ... an Order dated July 18th, U.S. District Judge Ed ... a $1,000 fee for the preservation and return of ... things, the Order noted that there is no evidence ...
(Date:7/23/2014)... (PRWEB) July 23, 2014 Bodybuilding.com, the ... online retailer of nutritional supplements, has officially opened the ... BPI SPORTS , the fastest growing sports nutrition company, ... , Brand of the Year, Best Tasting Protein of ... Protein Powder of the year - Whey-HD™, Pre-workout Supplement ...
Breaking Medicine News(10 mins):Health News:Rich Dad Education Charity Yard Sale Raises Over $650 for Habitat for Humanity of Lee and Hendry Counties 2Health News:ATA Seeks Speakers to Present at the World’s Largest Telemedicine, mHealth and Telehealth Conference 2Health News:Global Cardio Care Celebrates EECP Patient’s 100th Birthday 2Health News:DePuy Pinnacle Hip Lawsuits Move Forward, as Federal Judge Denies Hospital Bid for $1000 Explant Fee, Bernstein Liebhard LLP Reports 2Health News:DePuy Pinnacle Hip Lawsuits Move Forward, as Federal Judge Denies Hospital Bid for $1000 Explant Fee, Bernstein Liebhard LLP Reports 3Health News:DePuy Pinnacle Hip Lawsuits Move Forward, as Federal Judge Denies Hospital Bid for $1000 Explant Fee, Bernstein Liebhard LLP Reports 4Health News:Vote Now; BPI SPORTS is Nominated for Eight 2014 Bodybuilding.com Supplement Awards 2Health News:Vote Now; BPI SPORTS is Nominated for Eight 2014 Bodybuilding.com Supplement Awards 3
... Coaching Provides Caregiving Needed Resources and Coping Strategies , ... ... Leeza’s Place have teamed to provide online coaching for ... strategies. , , , , ,Working on concepts in “Take ...
... Networks, has joined Medeguide.com as Head of Advertising and Sponsorship ... ... Conrad, formerly Regional Managing Director for Admax Networks, has joined ... Medeguide,s online advertising and sponsorship activities. Medeguide is a new ...
... of information on multiple sclerosis medications and the financial help ... ... 2009 -- NeedyMeds, a national nonprofit, added a new resource page to ... page is a multiple sclerosis-specific source of help for those looking for ...
... Vega Tapped to Lead Health Care Improvement Firm,s Sales ... Associates, Inc. today announced the addition of Al Vega ... officer. Mr. Vega joins the company at a time ... sales and marketing efforts for the company. In particular, ...
... 20 The following is a statement of ... http://www.newscom.com/cgi-bin/prnh/20080918/CFTFKLOGO )The Campaign ... (D-OR) for his leadership role in Senate committee ... and Drug Administration (FDA) regulatory authority over tobacco ...
... The following is a statement of Matthew ... http://www.newscom.com/cgi-bin/prnh/20080918/CFTFKLOGO )The Campaign for ... for his leadership role in Senate committee approval ... Drug Administration (FDA) regulatory authority over tobacco products, ...
Cached Medicine News:Health News:Hummingbird Coaching Partners with Leeza's Place to Help Caregivers “Take Your Oxygen First” 2Health News:Hummingbird Coaching Partners with Leeza's Place to Help Caregivers “Take Your Oxygen First” 3Health News:Senior Advertising Executive Joins Medeguide 2Health News:New Source of Information on Multiple Sclerosis Medications 2Health News:Press Ganey Names Chief Sales and Marketing Officer 2Health News:Sen. Jeff Merkley Votes to Protect America's Kids From Tobacco 2Health News:Sen. Jeff Merkley Votes to Protect America's Kids From Tobacco 3Health News:Sen. Christopher Dodd Leads Fight to Protect America's Kids From Tobacco 2Health News:Sen. Christopher Dodd Leads Fight to Protect America's Kids From Tobacco 3
(Date:7/23/2014)... The Board of Directors of VirtualScopics, Inc. ... clinical trial imaging solutions, announced today that Eric ... chief executive officer, effective immediately.  Mr. Converse joined the ... held the positions of interim president and chief executive ... Charles E. Phelps , Ph.D., chairman of the company,s ...
(Date:7/23/2014)... , July 23, 2014 Research ... "Sensor Market in Consumer Healthcare by Application, Sensor ... to 2013 - 2020" report to their offering. ... There has been an increasing momentum for consumer healthcare ... and sophistication. The consumer healthcare will lessen the healthcare ...
(Date:7/23/2014)... and MOUNTAIN VIEW, Calif. ... a recognized leader in translational preclinical research, today unveiled ... www.surpassinc.com ), signaling the transformation of Surpass, corporate culture ... partner for our customers. This press release comes on ... integral hires were added to the Silicon Valley Team: ...
Breaking Medicine Technology:Eric T. Converse Named President And Chief Executive Officer Of VirtualScopics, Inc. 2Eric T. Converse Named President And Chief Executive Officer Of VirtualScopics, Inc. 3Eric T. Converse Named President And Chief Executive Officer Of VirtualScopics, Inc. 4Sensor Market in Consumer Healthcare (Patient Monitoring, Therapeutic, Handheld and Homecare, & Fitness and wellness) - Analysis & Forecast to to 2013 - 2020 2Sensor Market in Consumer Healthcare (Patient Monitoring, Therapeutic, Handheld and Homecare, & Fitness and wellness) - Analysis & Forecast to to 2013 - 2020 3SURPASS Launches New Company Logo and Corporate Website, Symbolizing Transformation of Company Culture to Meet the Changing Needs of Clients in the Life Science Community Today. 2SURPASS Launches New Company Logo and Corporate Website, Symbolizing Transformation of Company Culture to Meet the Changing Needs of Clients in the Life Science Community Today. 3
... SPRINGS, Fla., Sept. 28 Tigris Pharmaceuticals, Inc., a ... the appointment of Mr. Neil Flanzraich as Executive Chairman ... of Mr. Flanzraich is a very important milestone for ... and CEO of Tigris, adding, "Neil brings to Tigris ...
... Research Group (MRG), the global authority on medical technology ... valued at $41 million in 2010, with revenues doubling ... issues surrounding obesity, coupled with an expanding patient pool ... growth in the gastric band market through 2015. This ...
Cached Medicine Technology:Tigris Pharmaceuticals Appoints Neil Flanzraich to Executive Chairman of the Board 2Tigris Pharmaceuticals Appoints Neil Flanzraich to Executive Chairman of the Board 3While Ethicon Endo-Surgery and Allergan Remain Front-Runners in the $41 Million Gastric Band Market, Other Competitors Battle for Third Place, According to Millennium Research Group 2
... Hand Instruments were developed in surgeon's desire ... still having an instrument with the strength ... fear of the bending or breaking. Arthrotek ... to conform to the surgeon's hand. This ...
... Precision Hand Instruments were developed in surgeon's ... while still having an instrument with the ... the fear of the bending or breaking. ... manufactured to conform to the surgeon's hand. ...
... Hand Instruments were developed in surgeon's desire ... still having an instrument with the strength ... fear of the bending or breaking. Arthrotek ... to conform to the surgeon's hand. This ...
... Hand Instruments were developed in surgeon's desire ... still having an instrument with the strength ... fear of the bending or breaking. Arthrotek ... to conform to the surgeon's hand. This ...
Medicine Products: