Navigation Links
News from the November/December Issue of Molecular Medicine
Date:11/9/2009

Studying Genetic Variance Across the World is Critical in Understanding the Effects of Genes

(Vocus) November 9, 2009 -- Understanding patients’ ancestries can be extraordinarily valuable when analyzing and interpreting scientific results. In a multi-center genetics study that scanned the genomes of 4,000 people throughout Europe and found clear regional differences, Drs. Chao Tian and Michael F. Seldin of the University of California, Davis, in collaboration with Peter K. Gregersen, MD, of The Feinstein Institute for Medical Research, identified allele frequency differences among ethnic groups and subgroups. The finding, published in the November/December issue of Molecular Medicine, is critical in the analysis of genetic studies because not knowing an individual’s ancestry could result in statistical errors that alter the outcome of the study.

“Until now, scientists have depended on a person’s knowledge of their ancestral roots when they study human populations to look for risk genes,” said Dr. Gregersen, head of the Center for Genomics and Human Genetics at the Feinstein Institute. But even among racial groups there can be significant differences in the frequencies of certain genetic alleles.

In another important study published in this issue of Molecular Medicine, investigators in The Netherlands and in Argentina conducted the first study of a metabolic disorder called Erythropoietic Protoporphyria (EPP) in a sample of Argentinean patients. They identified several novel mutations that could eventually lead to new therapies for this serious condition. People with EPP have an accumulation of protoporphyin in their red blood cells, plasma, liver and bile. This causes serious photosensitivity that can lead to burning, itching, swelling and painful skin in sun-exposed areas.

Other intriguing studies appearing in the journal include stem cell expression patterns in endometriosis; and that the hunger hormone, ghrelin (proven to contain potent anti-inflammatory effects), prevented radiation-induced injury.

Molecular Medicine (www.molmed.org) is published by The Feinstein Institute for Medical Research. The peer-reviewed journal strives to understand normal body functioning and disease pathogenesis at the molecular level, which may allow researchers and physician-scientists to use that knowledge in the design of specific molecular tools for disease diagnosis, treatment, prognosis and prevention. The journal, a bimonthly publication, serves as a forum through which scientists and researchers can communicate recent discoveries to a multi-disciplinary, international audience interested in understanding and curing disease.

To listen to the latest podcast on these studies visit www.molmed.org/podcast.html.

Contact: Veronica J. Davis, Communications Editor, 516-562-2670

# # #

Read the full story at http://www.prweb.com/releases/Molecular_Medicine/genetics/prweb3180324.htm.


'/>"/>
Source: PRWeb
Copyright©2009 Vocus, Inc.
All rights reserved  

Related medicine news :

1. Annals of Internal Medicine tip sheet for Aug. 21, 2007, issue
2. Donate Life America Dispels Myths About Organ & Tissue Donation Among Hispanics During National Hispanic Heritage Month
3. College Mental Health Expert and Sister of Student Who Died By Suicide Available to Discuss College Mental Health Issues
4. AHCA: Rescinding $2.7 Billion Medicare Cuts Top Issue for Fall Legislative Agenda
5. Jump in Youth Suicide Prompts National Childrens Charity KidsPeace to Issue Tips on Prevention, Warning Signs
6. USC researcher identifies stem cells in tendons that regenerate tissue in animal model
7. PowerBar Issues Open Call for 2008-2009 PowerBar Team Elite(TM) Athlete Sponsorship Program
8. Crystal Research Associates, LLC Issues Executive Informational Overview(R) (EIO(R)) on Tapestry Pharmaceuticals, Inc.
9. American Red Cross Issues Blood Supply Alert
10. OSHA Issues Draft Ergonomics Guidelines on Preventing Musculoskeletal Injuries in Shipyards
11. Arbios Systems, Incs Q2/07 Analyst Review Issued by Scimitar Equity Research, Inc.
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
News from the November/December Issue of Molecular Medicine
(Date:6/27/2016)... (PRWEB) , ... June 27, ... ... in the patient payment industry today announced its strategic partnership with Connance, ... system workflows. , The two companies’ proven, proprietary technology combine to provide ...
(Date:6/26/2016)... California (PRWEB) , ... June 26, 2016 , ... Pixel ... Cut Pro X. , "Film editors can give their videos a whole new perspective ... Christina Austin - CEO of Pixel Film Studios. , ProSlice Levels contains over ...
(Date:6/25/2016)... ... , ... Austin residents seeking Mohs surgery services, can now turn to Dr. ... Russell Peckham for medical and surgical dermatology. , Dr. Dorsey brings specialization to include ... in Mohs Micrographic Surgery completed by Dr. Dorsey was under the direction of Glenn ...
(Date:6/25/2016)... ... June 25, 2016 , ... Dr. Calvin Johnson has ... he has implemented orthobiologic procedures as a method for treating his patients. The ... first doctors to perform the treatment. Orthobiologics are substances that orthopaedic surgeons use ...
(Date:6/24/2016)... ... June 24, 2016 , ... June 19, 2016 is ... associated with chronic pain and the benefits of holistic treatments, Serenity Recovery Center ... suffering with Sickle Cell Disease. , Sickle Cell Disease (SCD) is a disorder of ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 Roche (SIX: RO, ... clearance for its Elecsys BRAHMS PCT (procalcitonin) assay as ... or septic shock. With this clearance, Roche is the ... fully integrated solution for sepsis risk assessment and management. ... bacterial infection and PCT levels in blood can aid ...
(Date:6/23/2016)... , June 23, 2016 Research and ... News Issue 52" report to their offering. ... influenza treatment creates a favourable commercial environment for MedImmune to ... patient base that will serve to drive considerable growth for ... would serve to cap sales considerably, but development is still ...
(Date:6/23/2016)... PARK RIDGE, Ill. and INDIANAPOLIS ... caliber of students receiving a Lilly Diabetes Tomorrow,s Leaders ... hands. The 2016 scholarship winners, announced today online at ... refused to let type 1 diabetes stand in the ... Lilly Diabetes has supported the Foundation,s scholarship program since ...
Breaking Medicine Technology: