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News from the Latest Issue of Molecular Medicine
Date:1/12/2010

t regulates the estrogen responsive elements (EREs) of genes to stop the spread of ER-negative tumors. They used adenovirus infected ER-negative tumor cells derived from a breast adenocarcinoma. The monotransregulator repressed cell proliferation and infiltration and induced cell death by turning on genes required for the estrogen responsive elements to interact. “Specific regulation of genes bearing EREs could offer a therapeutic approach for de novo endocrine-resistant breast cancers,” the scientists said.

Enclosed is a table of contents for the latest issue. You can view all of the articles in the September-October issue by visiting the journal’s Web site at www.molmed.org.

Molecular Medicine is published by The Feinstein Institute for Molecular Research. The peer-reviewed journal strives to understand normal body functioning and disease pathogenesis at the molecular level, which may allow researchers and physician-scientists to use that knowledge in the design of specific molecular tools for disease diagnosis, treatment, prognosis, and prevention. The journal, a bimonthly publication, serves as a forum through which scientists and researchers can communicate recent discoveries to a multi-disciplinary, international audience interested in understanding and curing disease.

To listen to the latest podcast on these studies visit www.molmed.org/podcast.html.

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