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Date:7/12/2009

of total alcohol, type of alcoholic beverage, and drinking pattern with risks of total, low- and high-grade prostate cancer. They used data from more than 10,000 men participating in the Prostate Cancer Prevention Trial (PCPT). They found participants who reported heavy alcohol consumption (≥50 g alcohol/day) and regular heavy drinking (≥4 drinks/day on ≥5 days per week) were twice as likely or more to be diagnosed with high-grade prostate cancer (RR: 2.01, and 2.17, respectively). Less heavy drinking was not associated with risk. They also compared drinking patterns with treatment outcome among men enrolled on this placebo-controlled trial of the drug finasteride. They found finasteride's ability to lower prostate cancer risk was blocked in men drinking < 50g alcohol per day. They conclude heavy, daily drinking increases the risk of high-grade prostate cancer and that heavy drinking made finasteride ineffective for reducing prostate cancer risk.

Article: "Alcohol Consumption, Finasteride and Prostate Cancer Risk: Results from the Prostate Cancer Prevention Trial." Zhihong Gong, Alan R. Kristal, Jeannette M. Schenk, Catherine M. Tangen, Phyllis J. Goodman, and Ian M. Thompson. CANCER; Published Online: July 13, 2009 (DOI: 10.1002/cncr.24423); Print Issue Date: August 15, 2009

Contact: Kristen Lidke Woodward, Senior Media Relations Manager, Fred Hutchinson Cancer Research Center. Phone: 206-667-5095, Email: kwoodwar@fhcrc.org


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Contact: David Sampson
david.sampson@cancer.org
American Cancer Society
Source:Eurekalert

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