Navigation Links
News briefs from the January issue of Chest
Date:1/5/2010

SMALL, THIN CHILDREN MAY HAVE POORER LUNG FUNCTION

A new study shows that poor lung function during adolescence and through midlife may be influenced by several factors, including birth weight, height, and gender. Researchers from Newcastle University in the United Kingdom analyzed health data from 252 patients, all aged 14 years. Follow-up data also were obtained for 122 of the patients at age 49 to 51. Results showed that several factors were related to poorer lung function (as measured by FEV1) at age 14, including lower height, lower BMI, being breast-fed for less than 4 weeks, and childhood respiratory disease. Furthermore, several factors predicted a decline in lung function between the ages of 49 to 51 years, including more cigarettes smoked in the lifetime, having a higher FEV1 at age 14, and being female. Researchers note that women reach their maximum FEV1 at a younger age than men, which may explain why, after age 14, the lung function of women declines at a higher rate than the lung function of men. This article is published in the January issue of Chest, the peer-reviewed journal of the American College of Chest Physicians.

TIOTROPIUM ASSOCIATED WITH REDUCED MORTALITY

New research suggests that tiotropium, a long-acting anticholinergic used in patients with COPD, may be associated with a reduction in all-cause mortality, cardiovascular mortality, and cardiovascular events. Researchers from Caritas-St. Elizabeth Medical Center in Boston, MA, reviewed the outcomes of 30 completed clinical trials in the tiotropium project database. Within the trials, 10,846 patients were treated with tiotropium and 8,699 patients received a placebo. Results indicated that patients treated with tiotropium had lower incidence rates (IR) of all-cause mortality, cardiovascular mortality, and cardiovascular events (IR = 3.44, .91, and 2.15 per 100 patients, respectively), compared with placebo (IR = 4.10, 1.24, and 2.67, respectively). Within the tiotropium group, the overall risk for serious or fatal lower respiratory events also was reduced. The mechanism by which tiotropium may reduce cardiovascular mortality is unclear, but researchers speculate that there may be an association with the reduction in respiratory events. The article is published in the January issue of Chest, the peer-reviewed journal of the American College of Chest Physicians.

IPRATROPIUM BROMIDE MAY INCREASE RISK FOR CARDIOVASCULAR EVENTS

Patients taking ipratropium bromide, an anticholinergic used in the treatment of COPD, may be at an increased risk for cardiovascular events (CVE), including heart failure. Researchers from the University of Washington in Seattle, WA, and Hines VA Hospital in Hines, IL, conducted a cohort study on 82,717 US veterans with a new diagnosis of COPD between 1999 and 2002. Of the patients, 44 percent were exposed to anticholinergics (mainly ipratropium) at some time during the study. Patients were followed until they had their first hospitalization for a CVE, until they died, or until September 30, 2004. Within the cohort, 6,234 CVE were identified (44 percent heart failure, 28 percent acute coronary syndrome, and 28 percent dysrhythmias). Results showed that any exposure to anticholinergics within the past 6 months was associated with an increased risk of CVE. However, among patients who received anticholinergics more than 6 months prior, an elevated risk of CVE was not seen. Researchers note that their findings are consistent with previous concerns raised about the cardiovascular safety of ipratropium bromide. This study is published in the January issue of Chest, the peer-reviewed journal of the American College of Chest Physicians.


'/>"/>

Contact: Jennifer Stawarz
jstawarz@chestnet.org
847-498-8306
American College of Chest Physicians
Source:Eurekalert

Related medicine news :

1. News briefs from the journal Chest, August 2007
2. URAC Releases Issue Briefs Examining Stakeholders Views of Care Coordination Along the Healthcare Continuum
3. News briefs from the November issue of Chest
4. DuPont Group Vice President Briefs Investors on Performance Materials Segment
5. Nanotech Briefs Announces Call for Nominations for the Fourth Annual Nano 50(TM) Awards
6. News Briefs from Preventive Medicine 2008
7. Journal Chest -- March 2008 news briefs
8. News briefs: May issue of the journal Chest
9. Weill Cornell science briefs May 2008
10. News briefs from the American Society of Plastic Surgeons
11. News briefs from the American Society of Plastic Surgeons
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/23/2017)... ... June 23, 2017 , ... Jusino Insurance ... to communities in the greater Chicago metropolitan area, is embarking on a charity ... youth in Chicago. , Founded in 1897, Hephzibah Children’s Association is one of ...
(Date:6/22/2017)... CA (PRWEB) , ... June 22, 2017 , ... Plastic ... named as a Top Doctor for 2017. Each year, research and information firm, Castle ... First winning the title in 2015, this marks the 3rd time that Dr. ...
(Date:6/22/2017)... ... June 22, 2017 , ... The VA Maryland Health ... Network has awarded the Baltimore VA Medical Center, a division of the VA ... its efforts to promote waste reduction and promote recycling. Also, Practice Greenhealth ...
(Date:6/20/2017)... ... June 20, 2017 , ... Connance, a leading ... will present how predictive analytics drive reimbursement optimization, with a focus on denial ... 25-28. , “The traditional approach to denied and underpaid claims leaves money ...
(Date:6/20/2017)... , ... June 20, 2017 , ... Fresenius Vascular Care, ... minimally invasive techniques to treat and manage a wide range of vascular conditions, has ... initiative. With more than 65 centers represented by more than 40 local brands, a ...
Breaking Medicine News(10 mins):
(Date:6/11/2017)... 10, 2017  Eli Lilly and Company (NYSE: ... 3 studies of galcanezumab, an investigational treatment for the ... on several key secondary endpoints for galcanezumab compared to ... studies (EVOLVE-1, EVOLVE-2 and REGAIN) will be presented today ... in Boston . ...
(Date:6/8/2017)...   Responding to Heath Ledger,s father,s recent ... singer Chris Cornell in May, the mental health ... free online psychiatric drug side effects search ... psychotropic drug risks. The father of the ... accidental overdose, has called for tighter rules on prescription drugs. ...
(Date:6/5/2017)... 2017 The Cincinnati location ... Inc. (NYSE: DPLO), has been awarded a Top Workplaces ... Results are based on an employee survey administered by ... workplace improvement. The survey measures several aspects of workplace culture, ... ...
Breaking Medicine Technology: