Navigation Links
News brief: Contrast agent with MRI improves detection of lymph nodes metastases
Date:2/1/2010

Addition of the contrast agent gadolinium during magnetic resonance imaging (MRI) for primary tumor assessment improved accuracy for detecting lymph node metastases, according to a new study published online February 1 in the Journal of the National Cancer Institute. Gadolinium-enhanced MRI is primarily used to visualize primary tumors, highlight tumor vascularity, and increasingly to detect and evaluate lymph node metastases. In light of this systematic review, the authors recommend that contrast highlighting be included as a malignancy criterion when this agent is used for primary tumor visualization.

Wenche M. Klerkx, M.D., Ph.D., Department of Gynecology and Obstetrics, University Medical Centre Utrecht, the Netherlands, and colleagues searched the literature for studies that compared the diagnostic accuracy of gadolinium-enhanced MRI for staging lymph node metastases with that of histopathologic examination. The researchers conducted a meta-analysis that encompassed more than 30 studies from the last 10 years and reported summary sensitivity and specificity of MRI for detecting nodal metastases.

The researchers found that overall accuracy of gadolinium-enhanced MRI for the detection of nodal metastases was moderate. They also concluded that incorporating contrast enhancement in the malignancy criteria improves the accuracy of this diagnostic test.

"We further advocate the use of uniform malignancy criteria, including contrast enhancement, for standardization of future evaluations," the authors write. "Gadolinium enhancement by itself does not have the diagnostic accuracy to replace histopathologic examination of lymph nodes; however, it can help identify suspicious lymph nodes that should be surgically collected for histopathologic examination."

Study limitations: Not all of the included studies reported diagnostic study quality, which precluded formal analyses based on the quality assessment items. A reg
'/>"/>

Contact: Steve Graff
jncimedia@oxfordjournals.org
301-841-1285
Journal of the National Cancer Institute
Source:Eurekalert

Page: 1 2

Related medicine news :

1. News brief: Childhood survivors of CNS cancers and leukemia have lowered educational attainment
2. News brief: SNPs in C-reactive protein are not associated with increased risk of cancer
3. News brief: Knockdown of E2F1 reduces invasive potential of melanoma cells
4. News brief: Dermatologic infections in cancer patients treated with EGFRI therapy
5. News brief: Long-term testicular cancer survivors at high risk for neurological side effects
6. News brief: Estrogen receptor-alpha, breast cancer patients and tamoxifen response
7. News brief: Arsenic biomethylation required for oxidative DNA damage
8. News brief: Adverse symptom reporting by patients vs. clinicians
9. News brief: Effects of aspirin and folic acid on inflammation markers for colorectal adenomas
10. JNCI news brief: STD confirmed to be associated with increased risk of prostate cancer
11. JNCI news brief: Melanosome dynamics and sensitivity of melanoma cells to chemotherapy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/25/2014)... 25, 2014 The American Brain Tumor ... Talent Development Trainer of Distinguished Events, and Corporate and ... American Cancer Society, will be joining the ABTA in ... Ward will oversee the roll out of a nationwide ... , The recently launched volunteer network will provide the ...
(Date:7/25/2014)... Chicago, IL (PRWEB) July 25, 2014 “You ... of more than 500 people and their loved ones across ... Association (ABTA), a brain tumor diagnosis is typically met with ... learn a new and difficult vocabulary, and make critical decisions ... a brain tumor diagnosis is accompanied by a sense of ...
(Date:7/25/2014)... IL (PRWEB) July 25, 2014 Today, nearly ... tumor, and yet, when it comes to pinpointing causes or ... now, we don’t know who, we don’t know when, and ... M. Wilson, MNA, president & CEO, American Brain Tumor Association. ... the American Brain Tumor Association funds research to pursue answers ...
(Date:7/25/2014)... July 25, 2014 The North America Artificial ... in North America with analysis and forecast of revenue. The ... from around $4.7 billion in 2013 to around $7 billion ... 2018. , Browse through the TOC of North America ... analysis provided. This also provides a glimpse of the segmentation ...
(Date:7/25/2014)... 25, 2014 The report, "Wireless ... Wi-Fi, Wireless Gigabit Alliance, Access Points, Routers, Residential ... Technology Roadmap and Analysis (2014 - 2019)," provides ... overall market, segmented by WiGig enabled products, and ... segments of the WiGig market, and provides the ...
Breaking Medicine News(10 mins):Health News:American Brain Tumor Association Recruits Director to Lead New Volunteer Network 2Health News:American Brain Tumor Association to Expand Service Reach with Launch of Nationwide Volunteer Network 2Health News:American Brain Tumor Association to Expand Service Reach with Launch of Nationwide Volunteer Network 3Health News:Brain Tumor Causes and Risk Factors Elude Scientists 2Health News:Brain Tumor Causes and Risk Factors Elude Scientists 3Health News:Brain Tumor Causes and Risk Factors Elude Scientists 4Health News:North America Artificial Lift Services Market is Expected to Reach $7 Billion in 2018 - New Report by MicroMarket Monitor 2Health News:North America Artificial Lift Services Market is Expected to Reach $7 Billion in 2018 - New Report by MicroMarket Monitor 3Health News:North America Artificial Lift Services Market is Expected to Reach $7 Billion in 2018 - New Report by MicroMarket Monitor 4Health News:Wireless Gigabit (WiGig) Market Projected to $10.53 Billion by 2019 - New Report by MarketsandMarkets 2Health News:Wireless Gigabit (WiGig) Market Projected to $10.53 Billion by 2019 - New Report by MarketsandMarkets 3Health News:Wireless Gigabit (WiGig) Market Projected to $10.53 Billion by 2019 - New Report by MarketsandMarkets 4
... Jan. 10 Beginning Sunday, Jan. 10 and continuing through ... Disease Control (CDC) to promote National Influenza Vaccination Week. , ... nationwide effort to remind individuals it,s not too late to ... a serious disease. The Centers for Disease Control and Prevention ...
... ... (with over 65 clients in 24 states) announced today that several radiology practices in the ... Santa Fe Imaging in Santa Fe, NM, have signed contracts for billing and practice management ... Columbus, ...
... ... running plastic surgery practice in the nation is launching an expansive new ... Plastic Surgical Group, PC, a practice offering reconstructive and cosmetic surgery ... to provide web visitors with a thorough virtual tour of its facilities ...
... WASHINGTON, Jan. 8 Speaker Nancy Pelosi released the following statement on ... b y the Center for American Progress that ... over the next decade than would be created without reform. The report finds ... States by about 250,000 to 400,000 per year over the coming decade. ...
... ... , Health and Development Groups Applaud Clinton ... coalition of organizations representing millions of Americans applauded today,s statement by Secretary ... consensus that achieving universal access to reproductive health is critical for individual ...
... , , SILVER SPRING, Md., Jan. ... to stop producing and distributing its medical products used in ... compliance with FDA quality standards. The products are considered to ... review and approval for safety and effectiveness. The agreement was ...
Cached Medicine News:Health News:Highmark Supports National Influenza Vaccination Week 2Health News:Highmark Supports National Influenza Vaccination Week 3Health News:ADVOCATE Announces New Partnerships With Centers in the Western U.S. 2Health News:ADVOCATE Announces New Partnerships With Centers in the Western U.S. 3Health News:Long Island Plastic Surgical Practice - the Largest in the U.S. - Opens Virtual Doors on a New, State-of-the-Art Website 2Health News:Long Island Plastic Surgical Practice - the Largest in the U.S. - Opens Virtual Doors on a New, State-of-the-Art Website 3Health News:Long Island Plastic Surgical Practice - the Largest in the U.S. - Opens Virtual Doors on a New, State-of-the-Art Website 4Health News:U.S. Government Rejoins Worldwide Consensus on Reproductive Health 2Health News:U.S. Government Rejoins Worldwide Consensus on Reproductive Health 3Health News:U.S. Government Rejoins Worldwide Consensus on Reproductive Health 4Health News:U.S. Government Rejoins Worldwide Consensus on Reproductive Health 5Health News:U.S. Government Rejoins Worldwide Consensus on Reproductive Health 6Health News:U.S. Government Rejoins Worldwide Consensus on Reproductive Health 7Health News:FDA Requires Sybaritic, Inc. to Stop Producing Unapproved Medical Devices 2Health News:FDA Requires Sybaritic, Inc. to Stop Producing Unapproved Medical Devices 3
(Date:7/24/2014)... PARK, Kan. , July 24, 2014 /PRNewswire/ ... of two compounds that will be added to ... with Australian-based CIMTECH Pty Ltd, a biotechnology company. ... PAR 122 have shown promise in bone regeneration ... license to develop the compounds for the veterinary ...
(Date:7/24/2014)... MARSEILLE , Frankreich, July ... , Weltweite Exklusivlizenz der Universität ... Entwicklung von Tests auf SF3B1-Mutationen, einschließlich von ... Neuer Test weist Mutationen des SF3B1-Gens nach, ... einen günstigen Krankheitsverlauf vermuten lassen  ...
(Date:7/24/2014)... Calif., July 24, 2014  Abaxis, Inc. (NasdaqGS: ... blood analysis systems, today reported financial results for the ... First quarter overview: , Revenues of $47.5 million, ... Diluted EPS of $0.21, up 50% over last year,s ... market revenues of $7.2 million, up 20% over last ...
Breaking Medicine Technology:Parnell Acquires License for Intellectual Property and Rights to Develop Compounds for Bone and Dermal Regeneration 2Parnell Acquires License for Intellectual Property and Rights to Develop Compounds for Bone and Dermal Regeneration 3Parnell Acquires License for Intellectual Property and Rights to Develop Compounds for Bone and Dermal Regeneration 4QIAGEN erweitert Pipeline für die personalisierte Medizin um vielversprechende genomische Biomarker zur Prognosebestimmung bei Blutkrebsbehandlungen 2QIAGEN erweitert Pipeline für die personalisierte Medizin um vielversprechende genomische Biomarker zur Prognosebestimmung bei Blutkrebsbehandlungen 3QIAGEN erweitert Pipeline für die personalisierte Medizin um vielversprechende genomische Biomarker zur Prognosebestimmung bei Blutkrebsbehandlungen 4QIAGEN erweitert Pipeline für die personalisierte Medizin um vielversprechende genomische Biomarker zur Prognosebestimmung bei Blutkrebsbehandlungen 5Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 2Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 3Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 4Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 5Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 6Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 7Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 8Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 9Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 10Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 11
... (Nasdaq: ERES ), a global provider of ... device industries, today announced that Michael McKelvey will be ... Officer and a director of ERT.  The Company,s Board ...  Dr. McKelvey will continue in his current position until ...
... Sept. 10 Covance Inc. (NYSE: CVD ) ... Global Healthcare Conference on Tuesday, September 14, 2010 at 2:10 ... presentation at www.covance.com .  In order to register and ... Covance, with headquarters in Princeton, New Jersey, is ...
Cached Medicine Technology:ERT Announces Upcoming Retirement of Michael McKelvey as Chief Executive Officer 2ERT Announces Upcoming Retirement of Michael McKelvey as Chief Executive Officer 3
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: