Navigation Links
News brief: Contrast agent with MRI improves detection of lymph nodes metastases
Date:2/1/2010

Addition of the contrast agent gadolinium during magnetic resonance imaging (MRI) for primary tumor assessment improved accuracy for detecting lymph node metastases, according to a new study published online February 1 in the Journal of the National Cancer Institute. Gadolinium-enhanced MRI is primarily used to visualize primary tumors, highlight tumor vascularity, and increasingly to detect and evaluate lymph node metastases. In light of this systematic review, the authors recommend that contrast highlighting be included as a malignancy criterion when this agent is used for primary tumor visualization.

Wenche M. Klerkx, M.D., Ph.D., Department of Gynecology and Obstetrics, University Medical Centre Utrecht, the Netherlands, and colleagues searched the literature for studies that compared the diagnostic accuracy of gadolinium-enhanced MRI for staging lymph node metastases with that of histopathologic examination. The researchers conducted a meta-analysis that encompassed more than 30 studies from the last 10 years and reported summary sensitivity and specificity of MRI for detecting nodal metastases.

The researchers found that overall accuracy of gadolinium-enhanced MRI for the detection of nodal metastases was moderate. They also concluded that incorporating contrast enhancement in the malignancy criteria improves the accuracy of this diagnostic test.

"We further advocate the use of uniform malignancy criteria, including contrast enhancement, for standardization of future evaluations," the authors write. "Gadolinium enhancement by itself does not have the diagnostic accuracy to replace histopathologic examination of lymph nodes; however, it can help identify suspicious lymph nodes that should be surgically collected for histopathologic examination."

Study limitations: Not all of the included studies reported diagnostic study quality, which precluded formal analyses based on the quality assessment items. A reg
'/>"/>

Contact: Steve Graff
jncimedia@oxfordjournals.org
301-841-1285
Journal of the National Cancer Institute
Source:Eurekalert

Page: 1 2

Related medicine news :

1. News brief: Childhood survivors of CNS cancers and leukemia have lowered educational attainment
2. News brief: SNPs in C-reactive protein are not associated with increased risk of cancer
3. News brief: Knockdown of E2F1 reduces invasive potential of melanoma cells
4. News brief: Dermatologic infections in cancer patients treated with EGFRI therapy
5. News brief: Long-term testicular cancer survivors at high risk for neurological side effects
6. News brief: Estrogen receptor-alpha, breast cancer patients and tamoxifen response
7. News brief: Arsenic biomethylation required for oxidative DNA damage
8. News brief: Adverse symptom reporting by patients vs. clinicians
9. News brief: Effects of aspirin and folic acid on inflammation markers for colorectal adenomas
10. JNCI news brief: STD confirmed to be associated with increased risk of prostate cancer
11. JNCI news brief: Melanosome dynamics and sensitivity of melanoma cells to chemotherapy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... Dennis Thompson HealthDay Reporter ... first confirmed case of Ebola has surfaced in the United ... federal health officials announced late Tuesday. The critically ill ... Dallas, has been diagnosed with the deadly virus, officials ... in a late afternoon news conference. The man is ...
(Date:9/30/2014)... Health Day Reporter TUESDAY, ... who are overweight or obese when diagnosed appear to ... weight-related cancer, new research suggests. , , The finding ... only the potential for developing other cancers associated with ... who reported being overweight or obese prior to diagnosis ...
(Date:9/30/2014)... in 2003 to slow the spiraling costs of drugs ... patients has had no meaningful impact on cancer chemotherapy ... Journal of Clinical Oncology published online today. ... treat colorectal and lung cancers, and did not find ... following the implementation of the recent Medicare law in ...
(Date:9/30/2014)... Sept. 30, 2014 Research by UC Irvine immunologists ... shedding light on a vital process that determines how ... the online version of Nature Immunology , neurology ... other Institute for Immunology colleagues describe a critical mechanism ... into the bloodstream. , A T cell is a ...
(Date:9/30/2014)... Las Vegas, NV (PRWEB) September 30, 2014 ... by certified nutrition specialist and best-selling author Mike Geary that ... and totally transform their body into a fat-burning machine in ... Michaels, prompting an investigative review. , “In our culture ... it can be hard to decipher what is really fact ...
Breaking Medicine News(10 mins):Health News:CDC Confirms First Patient Diagnosed With Ebola in United States 2Health News:CDC Confirms First Patient Diagnosed With Ebola in United States 3Health News:Obesity Tied to Higher Cancer Risk for Colon Cancer Survivors 2Health News:Obesity Tied to Higher Cancer Risk for Colon Cancer Survivors 3Health News:Landmark Medicare law had little impact on reducing chemotherapy cost 2Health News:UCI study uncovers important process for immune system development 2Health News:Fat Burning Kitchen: Review Exposes Mike Geary’s 24-Hour Diet Transformation for Helping the Body Burn Fat Through a Natural Diet 2Health News:Fat Burning Kitchen: Review Exposes Mike Geary’s 24-Hour Diet Transformation for Helping the Body Burn Fat Through a Natural Diet 3
... risk of developing obesity. In the current issue of ... colleagues from Witten/Herdecke University describe possible ways to prevent ... 268-75). , There are many reasons that a ... the disability itself, for example, if this includes the ...
... ... Your Story” Diamond Contest. Shenoa will give away a 1-carat diamond ... to win the diamond contestants need only write a short story. Consumer ... is a way to show consumers they are appreciated by Shenoa. ...
... new study shows that a family of molecules called ... many important functions in healthy cells, but that in ... , The research, led by scientists at the Ohio ... and Richard J. Solove Research Institute in collaboration with ...
... mysteries of the animal world: why do females change the ... all year round? Researchers at the University of Gothenburg, Sweden, ... found some of the answers. What can millimetre-long water ... south-west Sweden have to say about animals, winter and summer ...
... from seven founding universities of the Global Alliance of ... at Shanghai Jiao Tong University to hold the 2010 ... Sustainable Urban Solutions. The latter coincides with ... Better Life. Senior representatives discussed the role of technological ...
... parents need more help with lifesaving drug regimens, study ... new study suggests that parents often make mistakes when ... , "Giving these medicines in exactly the right way ... conditions," said study lead author Dr. Kathleen E. Walsh, ...
Cached Medicine News:Health News:ShenoaDiamonds.com Holds Contest to Give Away $5,000 Diamond Ring, Spurred by Online Sales Growth 2Health News:Cancer cells show rewired, fragmented microRNA networks 2Health News:Large caps this spring's must-have for water fleas 2Health News:Global Alliance of Technological Universities (GlobalTech) to tackle 'Grand Challenges' 2Health News:Parent Error Common When Medicating Chronically Ill Kids 2
(Date:9/30/2014)... -- The Eastern European medical device industry is in ... as new medical-device manufacturers are constantly trying to penetrate ... to reduce the cost incurred for placing their products ... effective means to achieve this target. This research service ... and provides profiles of key distributors in ...
(Date:9/30/2014)... , Sept. 30, 2014 Passport Health, ... America , has launched FluFree.com, a website designed ... vaccinations. For 20 years, Passport Health has ... the flu. The launch of FluFree.com is designed to ... and the number of people who actually chose to ...
(Date:9/30/2014)... Ind. , Sept. 30, 2014  The orthopedic specialists ... the nation,s No. 6 orthopedic group by US News ... Active Adults," a series of free, public seminars to ... all over the world come to see the knee ... procedures are now available at Munster Specialty Surgery Center. ...
Breaking Medicine Technology:Medical Technologies Distributor Profiles in Eastern Europe 2Medical Technologies Distributor Profiles in Eastern Europe 3Passport Health Launches FluFree.com - Aims To Improve Flu Vaccination Rates and Fulfill Growing Public Health Priority 2Passport Health Launches FluFree.com - Aims To Improve Flu Vaccination Rates and Fulfill Growing Public Health Priority 3"Knee Pain Solutions for Active Adults" Complimentary Seminars Open to the Public 2
... 2011 Actavis, an international generic pharmaceutical company, today ... Extended-Release Tablets, a generic equivalent of Keppra XR®.  Shipping ... US total sales of approximately $161 million for the ... Health.   About Actavis: ...
... iKnowMed Electronic Health Record System (EHR) ... McKesson Specialty Health Solutions for Oncology , ... comprehensive chemotherapy orders workflow management system. Oncologists with both products ... which now automatically communicates with Lynx Mobile. This way, when ...
Cached Medicine Technology:Actavis Launches Generic Keppra XR® Tablets in the U.S. 2iKnowMed™ Integrates with Lynx Mobile® to Advance a Comprehensive Chemotherapy Management System 2iKnowMed™ Integrates with Lynx Mobile® to Advance a Comprehensive Chemotherapy Management System 3
The Optima III line of laparoscopic hand instruments provides a well-crafted set of instruments designed for strength and durability....
Inquire...
For use with Snap-In Snap-Out-II tip inserts. Available in five styles, the Snap-In Snap-Out-II Laparoscopic Instrument Handles offer the broadest range available....
Inquire...
Medicine Products: