Navigation Links
Newly found gene variants account for kidney diseases among African-Americans
Date:9/14/2008

For the first time, researchers have identified variations in a single gene that are strongly associated with kidney diseases disproportionately affecting African-Americans. This work was conducted by researchers at the National Institutes of Health (NIH) and by NIH-funded investigators at the Johns Hopkins University. The findings are published online today in two papers in Nature Genetics and will be published in the October print issue.

"These two breakthrough genomic studies on kidney disease illustrate the importance of collaborations between scientists at NIH and NIH-funded investigators at Johns Hopkins," said NIH Director Elias A. Zerhouni, M.D. "This type of government-academic collaboration moves translational research forward and provides the knowledge base for developing new therapies for these chronic health disorders."

The researchers studied nondiabetic kidney diseases that can lead to chronic kidney disease and, in severe cases, to kidney failure requiring long-term dialysis or a kidney transplant. One of these diseases, focal segmental glomerulosclerosis (FSGS), is a kidney disease that leads to kidney failure in more than half of those with the disease over a period of about 10 years. Chronic kidney disease is caused by many different diseases and conditions and affects 26 million Americans. More than 106,000 individuals develop kidney failure and more than 485,000 receive dialysis or transplantation in the United States each year.

Using a type of genome association that relies on differences in the frequency of gene variants between populations, the NIH researchers identified several variations in the MYH9 gene as major contributors to excess risk of kidney disease among African-Americans. The NIH researchers shared their discovery with the Johns Hopkins scientists, who replicated the findings in participants from earlier studies of kidney disease.

Both research teams found statistically significan
'/>"/>

Contact: Arthur Stone
niddkmedia@mail.nih.gov
301-496-3583
NIH/National Institute of Diabetes and Digestive and Kidney Diseases
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. McCulley/Cuppan Consultants Contribute Chapter to the Newly Published Book, Rhetoric of Healthcare: Essays Toward a New Disciplinary Inquiry
2. Newly-defined factors may prevent postpartum smoking relapse
3. Federal Advisory Committee Votes to Include Newly Licensed Pentacel(R) Vaccine in Vaccines for Children Program
4. Newly Formed Consortium to Combat Medical Fraud Announces National Agenda to Intensify Fight Against Health Care Fraud Goals: Collaboration Across Industries; Alignment of Resources; Increased Awareness Among Public and Private Stakeholders Including Fede
5. Newly approved ocular safety methods reduce animal testing
6. Worlds Leading Health Experts Urge Countries to Use Newly Released Data to Prevent the Death of Millions of Children Due to Rotavirus
7. IDM Pharma Announces Data Supporting Improved Overall Survival Advantage in Newly Diagnosed Patients with Metastatic Osteosarcoma Treated with Mifamurtide (L-MTP-PE)
8. Newly-Approved Cimzia(R) Provides Rapid, Sustained Response in Crohns Patients
9. Susan Byrne joins GHG Grey Healthcare Group as EVP, Strategy and Business Development, Europe, a Newly-Created Position
10. Newly Launched Regence Foundation to Help Transform Health Care and Influence the Nationwide Health Care Debate
11. Newly diagnosed breast cancer patients benefit from use of USFNA of lymph nodes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/3/2015)... ... 03, 2015 , ... E-Volve Health, an Elliot Health System ... organization, to provide electronic medical record (EMR) consulting services to Amerinet clients running ... negotiated pricing on E-Volve Health’s Epic EMR consulting, custom training and support services. ...
(Date:9/3/2015)... Lawrenceville, Georgia (PRWEB) , ... September 03, 2015 ... ... the spread of disease in Haiti, has partnered with Slingshot® Product Development Group ... no electricity or running water. Michael Wahl with DriButts plans to bring 600 ...
(Date:9/3/2015)... (PRWEB) , ... September 03, 2015 , ... ... care community to be situated at 4400 Columbine Drive in Bellingham, Washington. Silverado ... 2016, and has been carefully designed to serve up to 80 people living ...
(Date:9/3/2015)... San Jose, CA (PRWEB) , ... September 03, ... ... high-performance Splashtop remote desktop solution for LANDESK Management Suite customers, as part of ... Management Suite’s user-centered approach to IT, by delivering the best mobile user experience ...
(Date:9/3/2015)... ... , ... Girl’s Night Out to benefit Core Compassion Project will be held ... in Monroe, North Carolina. The event food will be provided by Kate ... offers off-premise catering and event services from casual to elegant. They are also the ...
Breaking Medicine News(10 mins):Health News:E-Volve Health to Offer EMR Consulting Solutions to Amerinet Members 2Health News:DriButts Diapers Rely on Slingshot Help in Haiti 2Health News:DriButts Diapers Rely on Slingshot Help in Haiti 3Health News:Site Dedication Ceremony to Celebrate New Silverado Memory Care Community 2Health News:Splashtop Partners with LANDESK to Deliver High Performance Remote Access and Remote Support to and from Mobile Devices and Chromebook 2Health News:Splashtop Partners with LANDESK to Deliver High Performance Remote Access and Remote Support to and from Mobile Devices and Chromebook 3Health News:Splashtop Partners with LANDESK to Deliver High Performance Remote Access and Remote Support to and from Mobile Devices and Chromebook 4Health News:Girl’s Night Out, with Food From Kate Clyde's Catered Creations, to Benefit Core Compassion Project 2
... Millions of postmenopausal women suffer from sexual dysfunctions- ... physiological and psychological problems. ,However if the ... these problems can be treated properly. Almost all ... develop changes in genital organs-particularly a condition known ...
... breast lumps are too small to be picked up by ... a potential candidate for breast cancer. But to offset this ... Baltimore headed by Dr. Saraswathi Sukumar, have devised a new ... a new method called ductal lavage. Ductal lavage, involves "washing" ...
... with diabetes, the most painful and bothering one is the ... part according to many diabetics is the finger stick. There ... times a day for more than ten to twenty years ... pain and discomfort associated with them. But researchers and manufacturers ...
... of Anti-dumping and Allied Duties, under the ministry ... duties on paracetamol from China and Taiwan. This ... used drug on basis of a petition filed ... and Sri Krishna Pharmaceuticals; Solapur based Vamsi Labs, ...
... therapy, complimentary and alternative medicine seem to be more ... new study. Among 191 HIV-positive outpatients surveyed about their ... had used alternative therapies at some point to control ... findings appear in the current issue of The journal ...
... wound healing in depressed people is four times slower than ... place in the latest issue of the journal, “Psychosomatic Medicine”. ... the rate of wound healing, according to the researchers. Depression ... immune system, which may keep a wound from healing on ...
Cached Medicine News:
(Date:9/3/2015)... NEW YORK , Sept. 3,  2015 ... organs are human-made bio-artificial devices, which are ... or support natural organs. These include artificial ... materials such as polymers (polyurethane, polysulfone, and ... used to develop artificial organs. These organs ...
(Date:9/3/2015)... Sept. 3, 2015 Nevro Corp. (NYSE: ... providing innovative evidence-based solutions for the treatment of chronic ... at the Morgan Stanley Global Healthcare Conference on Thursday, ... Nevro management is scheduled to present at 11:45 ... live audio webcast, accessible in the "Investors" section of ...
(Date:9/3/2015)... 3, 2015  As part of its ongoing commitment ... Marc R. Katz , MD, MPH, cardiac surgeon ... & Vascular Institute implanted the first HeartMate 3 left ... was selected as part of the prestigious MOMENTUM 3™ ... centers in the United States—and the first in central ...
Breaking Medicine Technology:Global Artificial Organ Market 2015-2019 2Bon Secours' Patient FIRST in Central Virginia to receive New Life-saving Care 2Bon Secours' Patient FIRST in Central Virginia to receive New Life-saving Care 3Bon Secours' Patient FIRST in Central Virginia to receive New Life-saving Care 4
... , SOUTH SAN FRANCISCO, Calif. , ... Bulletin Board: VXGN), announced today that Institutional Shareholder Services/Risk Metrics ... leading independent proxy advisory firms, recommend that VaxGen stockholders vote ... and "FOR" the Proposal to adjourn the VaxGen special meeting, ...
... , NEW YORK , Jan. 25 ... granted a license by the Virginia Department of Health to ... Virginia as a Private Review Agent (PRA). This license ... for commercial, Medicare, and Medicaid products offered by health plans, ...
Cached Medicine Technology:ISS/Risk Metrics Group and Glass Lewis Recommend VaxGen Stockholders Vote 'For' Proposed Merger With OXiGENE 2ISS/Risk Metrics Group and Glass Lewis Recommend VaxGen Stockholders Vote 'For' Proposed Merger With OXiGENE 3ISS/Risk Metrics Group and Glass Lewis Recommend VaxGen Stockholders Vote 'For' Proposed Merger With OXiGENE 4ISS/Risk Metrics Group and Glass Lewis Recommend VaxGen Stockholders Vote 'For' Proposed Merger With OXiGENE 5Care to Care Licensed to Manage High-cost Radiology in Virginia 2Care to Care Licensed to Manage High-cost Radiology in Virginia 3
Intended for the quantitative determination of urea nitrogen in serum. Reaction: kinetic. Wavelength: 340 nm. Linearity: 150 mg/dL (53.4 mmol/L urea) at 37C....
Intended for the quantitative determination of direct bilirubin in serum. Modified EvelynMalloy Method. Endpoint Reaction. Wavelength: 555 nm. Linearity: 20 mg/dl (340 mol/l)...
... microplate spectrophotometer designed specifically to run 24 ... With rugged hardware, proven optical performance and ... of traditional spectrophotometry to obtain results quickly, ... read up to eight, 1 cm Biocell ...
Spectra 3000RS & Spectra 3000RSP are very precise instruments. They have a metal base structure, durable parts for long life use, and they are very easy to use and maintain....
Medicine Products: