Navigation Links
Newly found gene variants account for kidney diseases among African-Americans
Date:9/14/2008

For the first time, researchers have identified variations in a single gene that are strongly associated with kidney diseases disproportionately affecting African-Americans. This work was conducted by researchers at the National Institutes of Health (NIH) and by NIH-funded investigators at the Johns Hopkins University. The findings are published online today in two papers in Nature Genetics and will be published in the October print issue.

"These two breakthrough genomic studies on kidney disease illustrate the importance of collaborations between scientists at NIH and NIH-funded investigators at Johns Hopkins," said NIH Director Elias A. Zerhouni, M.D. "This type of government-academic collaboration moves translational research forward and provides the knowledge base for developing new therapies for these chronic health disorders."

The researchers studied nondiabetic kidney diseases that can lead to chronic kidney disease and, in severe cases, to kidney failure requiring long-term dialysis or a kidney transplant. One of these diseases, focal segmental glomerulosclerosis (FSGS), is a kidney disease that leads to kidney failure in more than half of those with the disease over a period of about 10 years. Chronic kidney disease is caused by many different diseases and conditions and affects 26 million Americans. More than 106,000 individuals develop kidney failure and more than 485,000 receive dialysis or transplantation in the United States each year.

Using a type of genome association that relies on differences in the frequency of gene variants between populations, the NIH researchers identified several variations in the MYH9 gene as major contributors to excess risk of kidney disease among African-Americans. The NIH researchers shared their discovery with the Johns Hopkins scientists, who replicated the findings in participants from earlier studies of kidney disease.

Both research teams found statistically significan
'/>"/>

Contact: Arthur Stone
niddkmedia@mail.nih.gov
301-496-3583
NIH/National Institute of Diabetes and Digestive and Kidney Diseases
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. McCulley/Cuppan Consultants Contribute Chapter to the Newly Published Book, Rhetoric of Healthcare: Essays Toward a New Disciplinary Inquiry
2. Newly-defined factors may prevent postpartum smoking relapse
3. Federal Advisory Committee Votes to Include Newly Licensed Pentacel(R) Vaccine in Vaccines for Children Program
4. Newly Formed Consortium to Combat Medical Fraud Announces National Agenda to Intensify Fight Against Health Care Fraud Goals: Collaboration Across Industries; Alignment of Resources; Increased Awareness Among Public and Private Stakeholders Including Fede
5. Newly approved ocular safety methods reduce animal testing
6. Worlds Leading Health Experts Urge Countries to Use Newly Released Data to Prevent the Death of Millions of Children Due to Rotavirus
7. IDM Pharma Announces Data Supporting Improved Overall Survival Advantage in Newly Diagnosed Patients with Metastatic Osteosarcoma Treated with Mifamurtide (L-MTP-PE)
8. Newly-Approved Cimzia(R) Provides Rapid, Sustained Response in Crohns Patients
9. Susan Byrne joins GHG Grey Healthcare Group as EVP, Strategy and Business Development, Europe, a Newly-Created Position
10. Newly Launched Regence Foundation to Help Transform Health Care and Influence the Nationwide Health Care Debate
11. Newly diagnosed breast cancer patients benefit from use of USFNA of lymph nodes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/3/2015)... Pittsburgh, Pa (PRWEB) June 03, 2015 EMBARGOED ... , Lower Birth Weight Associated with Proximity of Mother’s Home ... women living close to a high density of natural gas ... babies with lower birth weights than women living farther from ... School of Public Health analysis of southwestern Pennsylvania birth ...
(Date:6/3/2015)... 03, 2015 Johnson & Johnson and ... million to resolve a Risperdal lawsuit ( http://www.risperdallawsuit2014.com/ ) ... company allegedly used to market the antipsychotic drug. ... that the Arkansas Attorney General moved to dismiss the ... The Risperdal settlement amounts to just a fraction of ...
(Date:6/3/2015)... Follow us on LinkedIn – ... treatment on account of their better mode of action ... rheumatoid arthritis. The industry is expected to witness a ... drugs to biopharmaceuticals over the coming years. The high ... therapies, and recombinant proteins has attracted industry players to ...
(Date:6/3/2015)... June 03, 2015 Dr. Steven Reisman, a ... Diagnostic Center ( http://www.newyorkcardiac.com ) located in NYC, announced today ... to his practice. In most cases, depending on the level ... day they call, they will be seen by a cardiologist ... as a cardiologist is to ensure that people who have ...
(Date:6/3/2015)... (PRWEB) June 03, 2015 VeoMed ... to expand online and mobile access to premier ... and Maintenance of Certification (MOC) activities. ... VeoMed’s innovative courses to Decker’s extensive lists of ... in purchasing access to VeoMed’s premier online and ...
Breaking Medicine News(10 mins):Health News:Fracking Proximity Associated with Lower Birth Weight 2Health News:Fracking Proximity Associated with Lower Birth Weight 3Health News:Fracking Proximity Associated with Lower Birth Weight 4Health News:Risperdal Lawsuit News: Johnson & Johnson, Janssen Settle Arkansas Marketing Case for $7.8 Million 2Health News:Risperdal Lawsuit News: Johnson & Johnson, Janssen Settle Arkansas Marketing Case for $7.8 Million 3Health News:Risperdal Lawsuit News: Johnson & Johnson, Janssen Settle Arkansas Marketing Case for $7.8 Million 4Health News:Superior Efficacy of Biopharmaceuticals Against Chronic Diseases Drives the Global Biopharmaceuticals Market, According to a New Report by Global Industry Analysts, Inc. 2Health News:Superior Efficacy of Biopharmaceuticals Against Chronic Diseases Drives the Global Biopharmaceuticals Market, According to a New Report by Global Industry Analysts, Inc. 3Health News:Superior Efficacy of Biopharmaceuticals Against Chronic Diseases Drives the Global Biopharmaceuticals Market, According to a New Report by Global Industry Analysts, Inc. 4Health News:NYC Cardiologist, Dr. Steven Reisman, Announces Same Day and Evening Appointments 2Health News:VeoMed and Decker Intellectual Properties, the Owner of Scientific American Medicine, Announce a Partnership to Expand Access to Premier Online CME Courses 2
... be especially diligent about having routine screening colonoscopies, results ... at Buffalo indicate. , Their findings show that persons ... polyps, known as adenomas, and advanced adenomas than men ... were presented Oct. 19 at a 10:30 a.m. session ...
... Dogs may not only be man,s best friend, they ... children with special needs. According to a new Universit de ... anxiety and enhance the socialization skills of children with Autism ... Psychoneuroendocrinology may be a relatively simple solution to help ...
... is not a foreign sight. But what about a turtle or ... fact, according to Gordon Burghardt, a psychology professor at the University ... monkeys -- need a little play time. "I studied ... never saw anything that I thought was play. Then I had ...
... SEATTLE, Wash.October 18, 2010Researchers at the Allen Institute for ... different activity patterns in the brain in individuals with ... individual differences in the effectiveness and side-effect profiles of ... The study is available in this week,s online early ...
... Oct. 19 (HealthDay News) -- People with depression and ... undergoing surgery, a new study suggests. U.S. researchers ... care units between Oct. 1, 2003 and Sept. 30, ... existing psychiatric condition, including 5,500 (15.5 percent) with depression, ...
... , MONDAY, Oct. 18 (HealthDay News) -- Invasive dental procedures ... heart attack and stroke, researchers say. But the increase ... "I don,t want to downplay this entirely, because we ... just after dental work was done among patients undergoing invasive ...
Cached Medicine News:Health News:Prostate cancer patients are at increased risk of precancerous colon polyps 2Health News:Children's best friend 2Health News:UT professor defines play, discovers even turtles need recess 2Health News:Gene activity in the brain depends on genetic background 2Health News:Depression, Anxiety May Raise Surgery Risks 2Health News:Invasive Dentistry May Raise Short-Term Heart, Stroke Risk 2Health News:Invasive Dentistry May Raise Short-Term Heart, Stroke Risk 3
(Date:6/3/2015)... SEATTLE , June 3, 2015 ... acquire Northeast Pharmaceuticals, Inc., bringing together two pharmacy organizations ... with mental illness. Both companies have strong reputations for ... their customers. Genoa ... the behavioral health community and those affiliated with managing ...
(Date:6/3/2015)... , June 3, 2015 Creekridge Capital, ... of its sales channels by adding two new sales ... as a Regional Sales Manager and Stefanie Stark ... Mr. Puma comes to Creekridge with over 20 ... his role at Creekridge, Mr. Puma will be responsible ...
(Date:6/3/2015)...  Halozyme Therapeutics, Inc. (NASDAQ: HALO ) ... with AbbVie (NYSE: ABBV ) to develop and ... ENHANZE ™ platform. Under ... an initial $23 million payment, followed by milestone ... up to nine collaboration targets. These payments are ...
Breaking Medicine Technology:Genoa, a QoL Healthcare Company Acquires Northeast Pharmaceuticals, Inc. 2Creekridge Capital Strengthens Sales Team 2Halozyme Enters Into Global Collaboration and Licensing Agreement With AbbVie 2Halozyme Enters Into Global Collaboration and Licensing Agreement With AbbVie 3
... 3, 2011 Reportlinker.com announces that a new market ... Probiotics and Prebiotics in Clinical Nutrition ... Introduction Overall sales of clinical nutrition ... US and EU as well as rising incidence of ...
... May 3, 2011 Researchers from the University of ... American Roentgen Ray Society 2011 Annual Meeting ... and reduce radiation exposure for breast cancer patients.   ... systems that can show the location as well as ...
Cached Medicine Technology:Reportlinker Adds Probiotics and Prebiotics in Clinical Nutrition 2Reportlinker Adds Probiotics and Prebiotics in Clinical Nutrition 3Reportlinker Adds Probiotics and Prebiotics in Clinical Nutrition 4Study Shows Same Day PET-Guided Biopsy May Expedite Pre-Operative Work-up For Breast Cancer Patients and Reduce Radiation Exposure 2
The TransNeb is a complete medication delivery system in a bag. The TransNeb is a compact, piston compressor providing high-performance while weighing only 11 oz. Versatility. Dependability. Simplici...
... A lightweight (4.2lbs) portable unit with a unique ... It features an oil free aluminum alloy integrated ... Available in a variety of combinations with ... Carrying bag is also available. , ...
The ACMI TurboFlow 18 L and 10 L Insufflators provide rapid distention for all laparoscopic procedures. Eleven built-in safety features make insufflation reliable and dependable....
... GenoID's kit is the first ... HPV for clinical diagnostic use. , ... high-risk and 5 low-risk genotypes of ... of PCR technology but simplifying the ...
Medicine Products: