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Newly established neuroscience clinical trials center could bring treatments to patients faster
Date:12/1/2011

December 1, 2011 In a development that could pave the way for treatment for rare neurological diseases and clues to more common ones, physician-scientists at Albert Einstein College of Medicine of Yeshiva University and Montefiore Medical Center, the University Hospital for Einstein, have secured a grant to establish a clinical site for the Network for Excellence in Neuroscience Clinical Trials (NeuroNEXT). One of only 25 such federally-funded centers in the country, the Einstein-Montefiore site was created in partnership with Einstein affiliates Beth Israel Medical Center in Manhattan and the North Shore-Long Island Jewish Health System. The NeuroNEXT network and its centers were established with grants from the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health.

NeuroNEXT was created to facilitate Phase II clinical trials for rare neurological diseases, which face significant challenges securing funding from industry, as well as with recruiting and retaining participants. (Phase II trials are conducted to assess how well and at what frequency and dosage a drug delivers effective results.) Should a promising drug be identified, enrolling enough participants with these rare disorders requires identifying and enlisting multiple sites around the country each of which can only contribute a few patients. Additionally, each has its own rigorous process in place to oversee such research.

These hurdles often prove insurmountable. By establishing a pre-existing network of sites and streamlining cumbersome logistics, the NeuroNEXT network and their centers aim to change that. "We'll basically be a S.W.A.T. team," said

Contact: Kim Newman
sciencenews@einstein.yu.edu
718-430-3101
Albert Einstein College of Medicine
Source:Eurekalert

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